Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Julie Massicotte"'
Publikováno v:
Drugs in R&D
Background Rapidly disintegrating or ‘fast-melt’ oral formulations have been developed recently to facilitate drug intake among patients. Even though these formulations have helped to improve therapy adherence, some of their limitations include:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703a46993f4432e2bcd129104c55232e
https://doi.org/10.1007/s40268-016-0132-1
https://doi.org/10.1007/s40268-016-0132-1
Autor:
Marianne Rufiange, Julie Massicotte, Patrick Colin, Mirela Iovu Niculita, Marc Lefebvre, Ariles Telmat, Jean-Michel Paquette, Maxime Ranger
Publikováno v:
Clinical Therapeutics. 36:1650-1664
Purpose Trimebutine 3-thiocarbamoylbenzenesulfonate (GIC-1001) is a new drug intended to be used for the management of visceral pain in patients undergoing sedation-free, full colonoscopy. The objectives of this Phase I, single-center, randomized, do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403aa4dba5eecd49f3ee27c0eed6ad3c
https://doi.org/10.1016/j.clinthera.2014.08.005
https://doi.org/10.1016/j.clinthera.2014.08.005
Autor:
Marc Lefebvre, Michael Grace, Jean-Sébastien Brunet, Jean Spénard, Christian Aumais, Julie Massicotte, Claude Tremblay
Publikováno v:
British Journal of Clinical Pharmacology. 60:374-377
Aims To evaluate the effects of food and formulation on the pharmacokinetics of bismuth biskalcitrate, metronidazole and tetracycline when combined in a new 3-in-1 single capsule (BMT) for eradication of Helicobacter pylori. Methods In a randomized,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800fbfbed32ec2f207c0322f37041be3
https://doi.org/10.1111/j.1365-2125.2005.02441.x
https://doi.org/10.1111/j.1365-2125.2005.02441.x
Publikováno v:
The Journal of Clinical Pharmacology. 44:640-645
The objective of this study was to determine the impact of omeprazole on bismuth (Bi) bioavailability when given in a three-in-one capsule containing bismuth biskalcitrate, metronidazole, and tetracycline. Thirty-four healthy volunteers were randomly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd0bff3be3c46fa2f7f978664c40d5c
https://doi.org/10.1177/0091270004265643
https://doi.org/10.1177/0091270004265643
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 66
To demonstrate bioequivalence (BE) between two prolonged-release (PR) drug formulations, single dose studies under fasting and fed state as well as at least one steady-state study are currently required by the European Medicines Agency (EMA). Recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d77e06af3b6e3e81b5dbc30e37bc0f
https://pubmed.ncbi.nlm.nih.gov/25312344
https://pubmed.ncbi.nlm.nih.gov/25312344
Publikováno v:
Cardiovascular Drugs and Therapy. 15:41-48
Abnormalities of T-type calcium channel function reported to occur in the transition phase to heart failure in the hamster cardiomyopathy may contribute to progression of the disease. We tested the hypothesis that chronic exposure to mibefradil, a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74841c11188b44927f17fc62d1e634c5
https://doi.org/10.1023/a:1011158717901
https://doi.org/10.1023/a:1011158717901
Publikováno v:
Issues in comprehensive pediatric nursing. 31(2)
Changes in health care delivery in Canada and Europe, especially the shift to ambulatory care, have modified the care that children and parents receive and have prompted the need for a partnership alliance. The objectives of this exploratory study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfd69ac7323b25b6aa46a12e67cbfc8
https://pubmed.ncbi.nlm.nih.gov/18569199
https://pubmed.ncbi.nlm.nih.gov/18569199
Publikováno v:
Clinical Chemistry. 44:2369-2371
Sugars have been used as probes for intestinal damage because healthy gastrointestinal tissue, unlike damaged mucosa, is almost totally impermeable to disaccharides (1)(2). Sutherland et al. (3) proposed the use of sucrose, which is degraded in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db979b0110d45f8afc349c87c7dbcb4
https://doi.org/10.1093/clinchem/44.11.2369
https://doi.org/10.1093/clinchem/44.11.2369
Autor:
Michael Grace, Julie Massicotte, Guy Aumais, Jean Spénard, Jean-Sébastien Brunet, Marc Lefebvre, Joelle Kasbo, Cynthia Cardinal, Claude Tremblay
Publikováno v:
Drugs in RD. 6(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1307475ea5cc9d23ba2c1f135b9fcc
https://pubmed.ncbi.nlm.nih.gov/15801866
https://pubmed.ncbi.nlm.nih.gov/15801866
Publikováno v:
Journal of cardiovascular pharmacology. 42(1)
Calcium channel blockers (CCBs) have variable efficacy in the treatment of heart failure. We hypothesized that modulation of left ventricular diastolic pressure (LVDP) may play a role in the variable efficacy of CCBs in this condition. Isolated perfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9769ae6d546bb8bef144e4d0471b0e
https://pubmed.ncbi.nlm.nih.gov/12827040
https://pubmed.ncbi.nlm.nih.gov/12827040