Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Julie Makani"'
Autor:
Philip Sasi, Abel Makubi, Raphael Z. Sangeda, Mariam Y. Ngaeje, Bruno P. Mmbando, Joseph Soka, Caterina Rosano, Alex S. Magesa, Sharon E. Cox, Julie Makani, Enrico M. Novelli
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-8 (2024)
Abstract Background Sickle cell anemia (SCA) prevalence remains high in sub-Saharan Africa. Long-term treatment with hydroxyurea (HU) increases survival, however, poor adherence to treatment could limit effectiveness. Whilst HU treatment adherence is
Externí odkaz:
https://doaj.org/article/6b1748037b71473fb053885fc70ad934
Autor:
Mike Nsubuga, Henry Mutegeki, Daudi Jjingo, Deogratias Munube, Ruth Namazzi, Robert Opoka, Philip Kasirye, Grace Ndeezi, Heather Hume, Ezekiel Mupere, Grace Kebirungi, Isaac Birungi, Jack Morrice, Mario Jonas, Victoria Nembaware, Ambroise Wonkam, Julie Makani, Sarah Kiguli
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Sub-Saharan Africa bears the highest burden of sickle cell disease (SCD) globally with Nigeria, Democratic Republic of Congo, Tanzania, Uganda being the most affected countries. Uganda reports approximately 20,000 SCD births annua
Externí odkaz:
https://doaj.org/article/7ed349685b024687b8a4f041f2828ce6
Autor:
Siana Nkya, Collin Nzunda, Emmanuel Saukiwa, Frida Kaywanga, Eliud Buberwa, David Solomon, Heavenlight Christopher, Doreen Ngowi, Julieth Johansen, Florence Urio, Josephine Mgaya, Salman Karim, Mohamed Zahir Alimohamed, Raphael Z. Sangeda, Clara Chamba, Emile R. Chimusa, Enrico Novelli, Julie Makani
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Background Pharmacogenomics of hydroxyurea is an important aspect in the management of sickle cell disease (SCD), especially in the era of genomic medicine. Genetic variations in loci associated with HbF induction and drug metabolism are pri
Externí odkaz:
https://doaj.org/article/d92c2a41448b440ea28e8f78c68c0d77
Autor:
Daima Bukini, Julie Makani, Joseph McCune, Dennis Lee, Cathy Bansbach, Serena De Vita, Dominic Kemps, Elianna Amin, Jonathan Spector, John Tisdale
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101287- (2024)
Therapeutic innovation to address sickle cell disease (SCD) is at a historical apex, characterized by a drug discovery, development, and commercialization landscape that includes potentially curative gene therapies. Given the wide geographic distribu
Externí odkaz:
https://doaj.org/article/61e617179782482faff6d68ead4aa67b
Autor:
Archana Shrestha, Biraj Man Karmacharya, Robert Kalyesubula, Isaac Ssinabulya, Zipporah Ali, Alma J Adler, Ana Olga Mocumbi, Neil Gupta, Meghnath Dhimal, Bhagawan Koirala, Gedeon Ngoga, Symaque Dusabeyezu, Gene Kwan, Gene Bukhman, Lilian Mbau, Beatriz Manuel, Giovanni Putoto, Santigie Sesay, Emily B Wroe, Yogeshwar Kalkonde, Sergio Chicumbe, Lauren Brown, Abha Shrestha, Lucia González, Matthew M Coates, Jones K Masiye, Mary Theodory Mayige, Wubaye Walelgne Dagnaw, Chiyembekezo Kachimanga, Ana Mocumbi, Ryan McBain, Apoorva Gomber, Fabio Manenti, Roma Chilengi, Yogesh Jain, Sam Patel, Gladwell Gathecha, Julie Makani, Amy McLaughlin, Celina Trujillo, Laura Drown, Reuben Mutagaywa, Todd Ruderman, Gina Ferrari, Chantelle Boudreaux, Humberto Muquingue, Mary Mayige, Jonathan Chiwanda Banda, Andrea Atzori, Neusa Bay, Wondu Bekele, Victoria M Bhambhani, Remy Bitwayiki Nkwiro, Dawson Calixte, Katia Domingues, Darius Fenelon, Innocent Kamali, Catherine Karekezi, Alexio Mangwiro, Fastone Mathew Goma, Emmanuel Mensah, Nicole Mocumbi Salipa, Alvern Mutengerere, Marta Patiño, Devashri Salvi, Fameti Taero, Emílio Tostão, Sterman Toussaint, Abhijit Gadewar, Sunil Jadhao, Chetanya Malik, Alma Adler, Victoria Bhambhani, Susan Donnellan, Kaita Domingues, Sheila Klassen, Andrew Marx, Maia Olsen, Catherine Player, Ramon Ruiz, Ada Thapa, Leslie Wentworth, Allison Westervelt, Ariana Wolgin, Emily Yale, Michael Abiyu, Lemma Ayele, Zelalem Mengistu, Temesgen Sileshi, Natnael Alemayehu, Natnael A Abebe, Nancy Larco, Gideon Ayodo, Peter Mokaya, Jones Masiye, Evelyn Chibwe, Noel Kasomekera, Nicole M Salipa, Riaze Rafik, Lucy Ramirez, Shiva Adhikary, Krishna Aryal, Phanindra Baral, Biraj Karmachaya, Abhinav Vaidhya, Ann Akiteng, Frank Mugabe, Sarah Asio Eragu, Bernard Bukar, Namasiku Siyumbwa, Wibroad Mutale, Kudakwashe Madzeke, Alaisa Mbiriri, Nyamayaro Wencelas, Porika Nyawai, Abaden Svisva, Laura Ruckstuhl
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction The Package of Essential Noncommunicable Disease Interventions—Plus (PEN-Plus) is a strategy decentralising care for severe non-communicable diseases (NCDs) including type 1 diabetes, rheumatic heart disease and sickle cell disease, to
Externí odkaz:
https://doaj.org/article/992bdf24e8ec4d74866d7214d725d384
Autor:
Hilda J. Tutuba, Agnes Jonathan, William Lloyd, Upendo Masamu, Emanuela Marco, Julie Makani, Paschal Ruggajo, Benson R. Kidenya, Irene K. Minja, Emmanuel Balandya
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Globally, Sickle cell disease (SCD) is one of the most common genetic disease with high childhood mortality. Early identification of babies with SCD through newborn screening (NBS) and linking them to care are among the recommende
Externí odkaz:
https://doaj.org/article/c2245b151355444abe742061815edf01
Publikováno v:
European Journal of Breast Health, Vol 19, Iss 1, Pp 28-33 (2023)
Objective:Cultural norms, community-specific cultural or religious beliefs, and resultant patient health-belief models are known to pose a significant but imperceptible barrier to breast cancer care. However, there is a paucity of data addressing the
Externí odkaz:
https://doaj.org/article/430a756a2a244a899ee0ffade8d4f20a
Autor:
Benard Mutua, Rose Chelangat, Barasa Mustafa, Tom Were, Julie Makani, George Sowayi, Patrick Okoth
Publikováno v:
The Egyptian Journal of Internal Medicine, Vol 34, Iss 1, Pp 1-12 (2022)
Abstract Background Western Kenya, being a malaria-endemic region, has a high prevalence of hemoglobinopathies mostly sickle cell and thalassemia. The hemoglobin fractions or variants, HbA, HbA2, and HbF, serve as biomarkers for the detection of hemo
Externí odkaz:
https://doaj.org/article/a98169b343254dd0b56438a5c4e18c6a
Autor:
Emmanuel Tebandite Kasai, Justin Ntokamunda Kadima, Jean Pierre Alworong’a Opara, François Boemer, Marie Françoise Dresse, Julie Makani, Vincent Bours, Roland Marini Djang’eing’a, Kambale-Kombi Paul, Salomon Batina Agasa
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 853-859 (2022)
Objectives HemoTypeSCTM is one of the immunoassay methods currently used for the early diagnosis of Sickle Cell Disease (SCD) in newborns. Earlier diagnosis remains the key strategy for early preventive care needs and parents’ education about the c
Externí odkaz:
https://doaj.org/article/40ea629c84384d7c92c69afce64d7507
Autor:
Sri Riyati Sugiarto, George M. Bwire, Brioni R. Moore, Madhu Page-Sharp, Laurens Manning, Kevin T. Batty, Omary M.S. Minzi, Billy Ngasala, Timothy M.E. Davis, Julie Makani, Sam Salman
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 19, Iss , Pp 31-39 (2022)
Since there are inconsistent data relating to the effect of haemoglobinopathies on disposition of artemisinin antimalarial combination therapy, and none in sickle cell trait (SCT) or sickle cell disease (SCD), the aim of this study was to characteriz
Externí odkaz:
https://doaj.org/article/78c6378ef8fc42d59de33b991703debb