Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Julie M. Nauroth"'
Autor:
Mark Yarchoan, Chiung‐Yu Huang, Qingfeng Zhu, Anna K. Ferguson, Jennifer N. Durham, Robert A. Anders, Elizabeth D. Thompson, Noah S. Rozich, Dwayne L. Thomas II, Julie M. Nauroth, Christina Rodriguez, Arsen Osipov, Ana De Jesus‐Acosta, Dung T. Le, Adrian G. Murphy, Daniel Laheru, Ross C. Donehower, Elizabeth M. Jaffee, Lei Zheng, Nilofer S. Azad
Publikováno v:
Cancer Medicine, Vol 9, Iss 4, Pp 1485-1494 (2020)
Abstract Background Mismatch repair proficient (MMRp) colorectal cancer (CRC) has been refractory to single‐agent programmed cell death protein 1 (PD1) inhibitor therapy. Colon GVAX is an allogeneic, whole‐cell, granulocyte‐macrophage colony‐
Externí odkaz:
https://doaj.org/article/d4ba8200190f4f8999ae7ef37f32141a
Autor:
Dung T. Le, Elizabeth M. Jaffee, Lisa M. Coussens, Dirk G. Brockstedt, Ludmila Danilova, Michael Considine, George A. Fisher, Margaret A. Tempero, Andrew H. Ko, Robert H. Vonderheide, Kim Reiss, Daniel A. Laheru, Elana J. Fertig, Robert A. Anders, Julie M. Nauroth, Beth Onners, Annie A. Wu, Elizabeth A. Sugar, Jennifer N. Durham, Todd Crocenzi, Takahiro Tsujikawa
Purpose:Two studies in previously treated metastatic pancreatic cancer have been completed combining GVAX pancreas vaccine (GM-CSF–secreting allogeneic pancreatic tumor cells) with cyclophosphamide (Cy) and CRS-207 (live, attenuated Listeria monocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1042d43fd930da9f558ec47c0ab13d59
https://doi.org/10.1158/1078-0432.c.6529254
https://doi.org/10.1158/1078-0432.c.6529254
Autor:
Dung T. Le, Elizabeth M. Jaffee, Lisa M. Coussens, Dirk G. Brockstedt, Ludmila Danilova, Michael Considine, George A. Fisher, Margaret A. Tempero, Andrew H. Ko, Robert H. Vonderheide, Kim Reiss, Daniel A. Laheru, Elana J. Fertig, Robert A. Anders, Julie M. Nauroth, Beth Onners, Annie A. Wu, Elizabeth A. Sugar, Jennifer N. Durham, Todd Crocenzi, Takahiro Tsujikawa
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ab01250e79e92a3ffe4f0e1470d6b6
https://doi.org/10.1158/1078-0432.22475994
https://doi.org/10.1158/1078-0432.22475994
Autor:
Amanda L. Huff, Saurav D. Haldar, Emily Davis-Marcisak, Thatcher Heumann, Gabriella Longway, Alexei Hernandez, Maximillian F. Konig, Brian Mog, Ludmila Danilova, Luciane Kagohara, Julie M. Nauroth, Amy M. Thomas, Elana J. Fertig, Won Jin Ho, Elizabeth M. Jaffee, Nilo Azad, Neeha Zaidi
Publikováno v:
Cancer Research. 83:LB197-LB197
Background: Oncogenic mutations in KRAS are expressed in up to 90% of pancreatic ductal adenocarcinomas (PDAC). Vaccination against mutant KRAS (mKRAS) is thus a promising approach as an off-the-shelf immunotherapeutic treatment for PDAC. We develope
Autor:
Saurav D. Haldar, Amanda Huff, Thatcher R. Heumann, Maureen Berg, Anna Ferguson, Su Jin Lim, Hao Wang, Amy M. Thomas, Julie M. Nauroth, Marina Baretti, Katherine M. Bever, Mark Yarchoan, Daniel A. Laheru, Elizabeth M. Jaffee, Nilofer S. Azad, Neeha Zaidi
Publikováno v:
Cancer Research. 83:CT036-CT036
Background: Novel strategies are needed to decrease the high recurrence rates of pancreatic ductal adenocarcinoma (PDAC) after curative-intent surgery. Mutant KRAS (mKRAS) is an oncogenic driver found in approximately 90% of PDAC that has emerged as
Autor:
Margaret A. Tempero, Elizabeth M. Jaffee, Michael Considine, Elana J. Fertig, Beth Onners, Takahiro Tsujikawa, Robert H. Vonderheide, Julie M. Nauroth, Andrew H. Ko, Lisa M. Coussens, Dung T. Le, Dirk G. Brockstedt, Jennifer N. Durham, Daniel A. Laheru, George A. Fisher, Todd S. Crocenzi, Robert A. Anders, Elizabeth A. Sugar, Kim A. Reiss, Ludmila Danilova, Annie A. Wu
Publikováno v:
Clin Cancer Res
Purpose: Two studies in previously treated metastatic pancreatic cancer have been completed combining GVAX pancreas vaccine (GM-CSF–secreting allogeneic pancreatic tumor cells) with cyclophosphamide (Cy) and CRS-207 (live, attenuated Listeria monoc
Autor:
Elizabeth D. Thompson, Carol Judkins, Brian J. Christmas, Katherine M. Bever, Nita Ahuja, Jiajia Zhang, Dwayne L. Thomas, Elizabeth M. Jaffee, Ernie A. Diaz Rivera, Julie M. Nauroth, Robert A. Anders, Meizheng Liu, Gary L. Rosner, Nilofer S. Azad, Qingfeng Zhu, Lei Zheng
Publikováno v:
Clinical Epigenetics
Epigenetic therapies may modulate the tumor microenvironment. We evaluated the safety and optimal sequence of combination DNA methyltransferase inhibitor guadecitabine with a granulocyte macrophage-colony-stimulating-factor (GM-CSF) secreting colon c
Autor:
Lei Zheng, Dwayne L. Thomas, Elizabeth M. Jaffee, Dung T. Le, Julie M. Nauroth, Noah Rozich, Anna Ferguson, Nilofer S. Azad, Jennifer N. Durham, Ana De Jesus-Acosta, Mark Yarchoan, Ross C. Donehower, Arsen Osipov, Adrian Murphy, Robert A. Anders, Christina Rodriguez, Elizabeth D. Thompson, Daniel A. Laheru, Qingfeng Zhu, Chiung Yu Huang
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 9, Iss 4, Pp 1485-1494 (2020)
Cancer Medicine, Vol 9, Iss 4, Pp 1485-1494 (2020)
Background Mismatch repair proficient (MMRp) colorectal cancer (CRC) has been refractory to single‐agent programmed cell death protein 1 (PD1) inhibitor therapy. Colon GVAX is an allogeneic, whole‐cell, granulocyte‐macrophage colony‐stimulati
Publikováno v:
Inflammation Research. 62:1003-1013
This study was designed to determine the anti-inflammatory activity of docosahexaenoic acid (DHA), alone and in combination with eicosapentaenoic acid (EPA), in a murine model of rheumatoid arthritis, collagen induced arthritis (CIA). The CIA was ind
Autor:
Kumar S.D. Kothapalli, Ying Chun Liu, Julie M. Nauroth, J. Paul Zimmer, B. Blank, Woo Jung Park, J. Thomas Brenna, Cynthia Tyburczy, Norman Salem
Publikováno v:
British Journal of Nutrition. 107:809-816
In the USA, infant formulas contain long-chain PUFA arachidonic acid (ARA) and DHA in a ratio of 2:1 and comprise roughly 0·66 g/100 g and 0·33 g/100 g total fatty acids (FA). Higher levels of dietary DHA appear to provide some advantages in visual