Výsledky vyhledávání - "Julie M. Moores"

Potent Cyclic Monomeric and Dimeric Peptide Inhibitors of VLA-4 (?4?1 Integrin)-Mediated Cell Adhesion Based on the Ile-Leu-Asp-Val Tetrapeptide

Autor: Anand S. Dutta, Amanda Rees, Alec Jamieson, Duncan Haworth, Rod S. Kittlety, Lorraine A. Hassall, Paul Gellert, James J. Gormley, Christopher F. Reilly, Peter J. Alcock, Christopher F. Hayward, Linda J. Wood, Mandy L. Crowther, Julie M. Moores

Publikováno v: Journal of Peptide Science. 6:321-341

Potent monomeric and dimeric cyclic peptide very late antigen-4 (VLA-4) inhibitors have been designed based on a tetrapeptide (Ile-Leu-Asp-Val) sequence present in a 25-amino acid peptide (CS-1) reported in the literature. The peptides, synthesized b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25ceb93494fef4de3a60f6b947f394cc
https://doi.org/10.1002/1099-1387(200007)6:7<321::aid-psc259>3.0.co

Zobrazit plný text záznamu

Potent cyclic peptide inhibitors of VLA-4 (?4?1 integrin)-mediated cell adhesion. Discovery of compounds like cyclo(MePhe-Leu-Asp-Val-d-Arg-d-Arg) (ZD7349) compatible with depot formulation

Autor: Paul Gellert, Peter J. Alcock, Duncan Haworth, Anand S. Dutta, Tracy Halterman, Roger Ferguson, Linda J. Wood, Julie M. Moores, Lorraine A. Hassall, Christopher F. Hayward, James J. Gormley, Christopher F. Reilly, Matthew M Coath, Jackie Moors, Amanda Rees, Rod S. Kittlety, Alec Jamieson

Publikováno v: Journal of Peptide Science. 6:398-412

Additional structure–activity relationship studies on potent cyclic peptide inhibitors of very late antigen-4 (VLA-4) are reported. The new N- to C-terminal cyclic hexa-, hepta- and octapeptide inhibitors like cyclo(MeIle/MePhe-Leu-Asp-Val-X) (X=2�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76652a961e3b5a12e5486a93642eb39f
https://doi.org/10.1002/1099-1387(200008)6:8<398::aid-psc270>3.0.co

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání