Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julie M. Lebert"'
Publikováno v:
Chemistry of Materials. 23:3685-3691
Protein microarrays based on pin-printing of sol–gel-entrapped biomolecules have emerged as a potential tool to accelerate drug screening and discovery. However, while materials have recently been identified that are suitable for printing of high-d
Autor:
Roger E. Luckham, Lauren M. Davies, Julie M. Lebert, Carlos D. M. Filipe, Anne Marie Smith, S. M. Zakir Hossain, John D. Brennan, Robert Pelton
Publikováno v:
Analytical Chemistry. 81:5474-5483
There is an increasing interest in new strategies to rapidly detect analytes of clinical and environmental interest without the need for sophisticated instrumentation. As an example, the detection of acetylcholinesterase (AChE) inhibitors such as neu
Publikováno v:
Organometallics. 28:2986-2992
Functionalized carborane complexes of the [M(CO)2(NO)]2+ (M = Re, 99mTc) core have potential utility as matched pairs of probes for correlated optical (M = Re) and scintigraphic (M = 99mTc) imaging...
Publikováno v:
Biochemistry and Cell Biology. 86:100-110
With compound libraries exceeding one million compounds, the ability to quickly and effectively screen these compounds against relevant pharmaceutical targets has become crucial. Solid-phase assays present several advantages over solution-based metho
Autor:
Jerald J. Nair, John D. Brennan, Julie M. Lebert, James McNulty, Maria Rowena N. Monton, Jessamyn R. L. Little
Publikováno v:
Analytical chemistry. 82(22)
A fluorimetric acetylcholinesterase (AChE) assay was developed and characterized both in solution and with the enzyme entrapped in sol-gel-derived silica. The assay is based on a disulfide-thiol interchange reaction between the intramolecularly quenc
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 86(2)
With compound libraries exceeding one million compounds, the ability to quickly and effectively screen these compounds against relevant pharmaceutical targets has become crucial. Solid-phase assays present several advantages over solution-based metho
Publikováno v:
Chemistry of Materials; Aug2011, Vol. 23 Issue 16, p3685-3691, 7p