Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Julie M, Williams"'
Autor:
Delphine C. Malherbe, Arban Domi, Mary J. Hauser, Caroline Atyeo, Stephanie Fischinger, Matthew A. Hyde, Julie M. Williams, Galit Alter, Farshad Guirakhoo, Alexander Bukreyev
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract A new vectored vaccine MVA-VLP-SUDV was generated against Sudan ebolavirus (SUDV) combining the advantages of the immunogenicity of a live attenuated vaccine vector (Modified Vaccinia Ankara, MVA) with the authentic conformation of virus-lik
Externí odkaz:
https://doaj.org/article/879a977d02bd49479bcc0f56d51a4c07
Autor:
Delphine C. Malherbe, Drishya Kurup, Christoph Wirblich, Adam J. Ronk, Chad Mire, Natalia Kuzmina, Noor Shaik, Sivakumar Periasamy, Matthew A. Hyde, Julie M. Williams, Pei-Yong Shi, Matthias J. Schnell, Alexander Bukreyev
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract The development of effective countermeasures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the COVID-19 pandemic, is a priority. We designed and produced ConVac, a replication-competent vesic
Externí odkaz:
https://doaj.org/article/ebf985f490e445e383c6a2b50cb40eb9
Autor:
John-Poul Ng-Blichfeldt, Benjamin J. Stewart, Menna R. Clatworthy, Julie M. Williams, Katja Röper
SummaryDuring kidney development, nephron epithelia arisede novofrom fate-committed mesenchymal progenitors through a mesenchymal-to-epithelial transition (MET). Downstream of fate specification, transcriptional mechanisms that drive establishment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c133121a7a7a1b4f422279109ac7af7
https://doi.org/10.1101/2023.04.30.538857
https://doi.org/10.1101/2023.04.30.538857
Autor:
Gabriela Baldeon Vaca, Michelle Meyer, Ana Cadete, Chiaowen Joyce Hsiao, Anne Golding, Albert Jeon, Eric Jacquinet, Emily Azcue, Chenxia Monica Guan, Xavier Sanchez-Felix, Colette A. Pietzsch, Chad E. Mire, Matthew A. Hyde, Margaret E. Comeaux, Julie M. Williams, Jean C. Sung, Andrea Carfi, Darin K. Edwards, Alexander Bukreyev, Kapil Bahl
Intranasal vaccination represents a promising approach for preventing disease caused by respiratory pathogens by eliciting a mucosal immune response in the respiratory tract that may act as an early barrier to infection and transmission. This study i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841d4ed2996e59a973df5d2c20fc6e56
https://doi.org/10.1101/2023.01.11.523616
https://doi.org/10.1101/2023.01.11.523616
Autor:
Alexander Bukreyev, Natalia Kuzmina, Adam J. Ronk, Matthias J. Schnell, Julie M. Williams, Chad E. Mire, Noor F. Shaik, Sivakumar Periasamy, Drishya Kurup, Christoph Wirblich, Pei Yong Shi, Delphine C. Malherbe, Matthew A. Hyde
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
NPJ Vaccines
NPJ Vaccines
The development of effective countermeasures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the COVID-19 pandemic, is a priority. We designed and produced ConVac, a replication-competent vesicular stom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33d0d7f27d270062d245d3559900ab6
https://doi.org/10.1101/2021.01.29.428442
https://doi.org/10.1101/2021.01.29.428442
Autor:
Samantha P Tull, Anne Bevins, Sahithi Jyothsna Kuravi, Simon C Satchell, Bahjat Al-Ani, Stephen P Young, Lorraine Harper, Julie M Williams, George Ed Rainger, Caroline O S Savage
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43916 (2012)
Neutrophil proteases, proteinase-3 (PR3) and elastase play key roles in glomerular endothelial cell (GEC) injury during glomerulonephritis. Endothelial protease-activated receptors (PARs) are potential serine protease targets in glomerulonephritis. W
Externí odkaz:
https://doaj.org/article/a2e295cee5e945f693e5615d7542b4eb
Autor:
Caroline O.S. Savage, Julie M. Williams, Lavanya Kamesh, Joanne Heward, Lorraine Harper, Alan D. Salama, Charles D. Pusey, Stephen Gough, Konstantia-Maria Chavele
OBJECTIVE: To investigate whether single nucleotide polymorphisms (SNPs) within cytotoxic T-lymphocyte antigen-4 (CTLA-4) are associated with ANCA-associated small vessel vasculitis (SVV). METHODS: The CTLA-4 CT60 (exon 4), +49 (exon 1) and -318 (pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79c017e3f9cbf03141f4e1fc76b5da8
https://ora.ox.ac.uk/objects/uuid:ad28fdb4-e6ef-4af5-ba17-ead294b3a988
https://ora.ox.ac.uk/objects/uuid:ad28fdb4-e6ef-4af5-ba17-ead294b3a988
Autor:
Lorraine Harper, Julie M. Williams, Caroline O. S. Savage, Michael J.O. Wakelam, Neil Holden, Stephen P. Young
Publikováno v:
Molecular Medicine. 17:1242-1252
Dysregulated release of neutrophil azurophilic granules causes increased tissue damage and amplified inflammation during autoimmune disease. Antineutrophil cytoplasmic antibodies (ANCAs) are implicated in the pathogenesis of small vessel vasculitis a
Autor:
Julie M. Williams, Tanya Pankhurst, Caroline O. S. Savage, R. Colman, Abdullah Hussain, Gerard B. Nash
Publikováno v:
Clinical and Experimental Immunology. 164:218-226
Summary Immunoglobulin G (IgG) is a potent neutrophil stimulus, particularly when presented as anti-neutrophil cytoplasm antibody (ANCA) in ANCA-associated vasculitis. We assessed whether IgG subclasses had differential effects on neutrophil activati
Autor:
Sarah Perkins, Timothy H.J. Goodship, Chris Taylor, Sally A. Johnson, Caroline O. S. Savage, Anna Richards, Bryan Paul Morgan, Kevin J. Marchbank, Julie M. Williams, Svetlana Hakobyan
Publikováno v:
Molecular Immunology. 47:1585-1591
Atypical hemolytic uremic syndrome (aHUS) is associated with mutations in the gene CFH encoding the complement regulator factor H (CFH). We previously reported a family, in which three individuals had partial CFH deficiency but only one was affected