Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Julie Leignadier"'
Autor:
Julie Leignadier, Marie Drago, Olivier Lesouhaitier, Magalie Barreau, Albert Dashi, Oliver Worsley, Joan Attia-Vigneau
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2083 (2023)
Acne is a chronic inflammatory skin disease that affects the quality of life of patients. Several treatments exist for acne, but their effectiveness tends to decrease over time due to increasing resistance to treatment and associated side effects. To
Externí odkaz:
https://doaj.org/article/34817523271a428c8da51ae7fb744ee1
Autor:
Gregory Segala, Marion David, Philippe de Medina, Mathias C. Poirot, Nizar Serhan, François Vergez, Aurelie Mougel, Estelle Saland, Kevin Carayon, Julie Leignadier, Nicolas Caron, Maud Voisin, Julia Cherier, Laetitia Ligat, Frederic Lopez, Emmanuel Noguer, Arnaud Rives, Bruno Payré, Talal al Saati, Antonin Lamaziere, Gaëtan Despres, Jean-Marc Lobaccaro, Silvere Baron, Cecile Demur, Fabienne de Toni, Clément Larrue, Helena Boutzen, Fabienne Thomas, Jean-Emmanuel Sarry, Marie Tosolini, Didier Picard, Michel Record, Christian Récher, Marc Poirot, Sandrine Silvente-Poirot
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Dendrogenin A, cholesterol metabolite, has tumor suppressive properties but the mechanisms are unknown. Here the authors show that Dendrogenin A can induce autophagy-mediated cell death in both melanoma and acute myeloid leukaemia.
Externí odkaz:
https://doaj.org/article/0e94ef7a2a0944adb3f0ebb1ddc02cb8
Autor:
Christine Gonzales, Hikari A I Yoshihara, Nahzli Dilek, Julie Leignadier, Melita Irving, Pascal Mieville, Lothar Helm, Olivier Michielin, Juerg Schwitter
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164557 (2016)
19F-MRI and 19F-MRS can identify specific cell types after in-vitro or in-vivo 19F-labeling. Knowledge on the potential to track in-vitro 19F-labeled immune cells in tumor models by 19F-MRI/MRS is scarce.To study 19F-based MR techniques for in-vivo t
Externí odkaz:
https://doaj.org/article/08d69f19a9484305a5ad23198545dd36
Autor:
Julie Leignadier, Nathalie Labrecque
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13740 (2010)
The generation of long-lived memory T cells is critical for successful vaccination but the factors controlling their differentiation are still poorly defined. We tested the hypothesis that the strength of T cell receptor (TCR) signaling contributed t
Externí odkaz:
https://doaj.org/article/9ad6fce18d124853bf46d897a05234fd
Publikováno v:
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2017, 144, pp.18-28. ⟨10.1016/j.bcp.2017.06.120⟩
Biochemical Pharmacology, 2017, 144, pp.18-28. ⟨10.1016/j.bcp.2017.06.120⟩
Biochemical Pharmacology, Elsevier, 2017, 144, pp.18-28. ⟨10.1016/j.bcp.2017.06.120⟩
Biochemical Pharmacology, 2017, 144, pp.18-28. ⟨10.1016/j.bcp.2017.06.120⟩
International audience; Breast cancer (BC) is one of the most common female cancers in the world, with estrogen receptor (ER)-positive BC the most frequent subtype. Tamoxifen (Tam) is an effective drug that competitively binds to the ER and is routin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2764e174c5c155a84202d9d1b6eb2d99
https://www.hal.inserm.fr/inserm-02380608/document
https://www.hal.inserm.fr/inserm-02380608/document
Autor:
Loubna Mhamdi, Maud Voisin, Camille Franchet, Emmanuel Noguer, Léonor Chaltiel, Marc Poirot, Elodie Bacquié, Philippe Rochaix, Arnaud Mallinger, Aurélie Mougel, Thomas Filleron, Chiara Zerbinati, Vincent Cavaillès, Magali Lacroix-Triki, Julie Leignadier, Frédéric Lopez, Nizar Serhan, Sandrine Silvente-Poirot, Luigi Iuliano, Emilie Huc-Claustre, Gregory Segala, Talal Al Saati, Laetitia Ligat, Regis Soules, Michel Record, Raphaëlle Duprez-Paumier, Florence Dalenc, Philippe de Medina
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
International audience; Breast cancer (BC) remains the primary cause of death from cancer among women worldwide. Cholesterol-5,6-epoxide (5,6-EC) metabolism is deregulated in BC but the molecular origin of this is unknown. Here, we have identified an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7379b46392db086e832aa7d1255938
https://europepmc.org/articles/PMC5676900/
https://europepmc.org/articles/PMC5676900/
Autor:
Julie Leignadier, Marc Poirot, Sandrine Silvente-Poirot, Luigi Iuliano, Chiara Zerbinati, Arnaud Rives, Regis Soules, Emmanuel Noguer, Philippe de Medina
Publikováno v:
Chemistry and Physics of Lipids
Chemistry and Physics of Lipids, Elsevier, 2017, 207, pp.92-98. ⟨10.1016/j.chemphyslip.2017.05.006⟩
Chemistry and Physics of Lipids, 2017, 207, pp.92-98. ⟨10.1016/j.chemphyslip.2017.05.006⟩
Chemistry and Physics of Lipids, Elsevier, 2017, 207, pp.92-98. ⟨10.1016/j.chemphyslip.2017.05.006⟩
Chemistry and Physics of Lipids, 2017, 207, pp.92-98. ⟨10.1016/j.chemphyslip.2017.05.006⟩
International audience; 5,6α-epoxycholesterol (5,6α-EC) and 5,6β-epoxycholesterol (5,6β-EC) are oxysterols involved in the anticancer pharmacology of the widely used antitumor drug tamoxifen. They are both metabolized into cholestane-3β,5α,6β-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd9d9d80e333d7e822d8f6b056221c0
https://www.hal.inserm.fr/inserm-02380612/file/1-s2.0-S0009308417300026-main.pdf
https://www.hal.inserm.fr/inserm-02380612/file/1-s2.0-S0009308417300026-main.pdf
Autor:
Arnaud Rives, Philippe de Medina, Claude Netter, Julie Leignadier, Emmanuel Noguer, Emilie Huc-Claustre, Citra Nagarathinam, Nizar Serhan, Regis Soules, Marc Poirot, Sandrine Silvente-Poirot
Publikováno v:
Chemistry and Physics of Lipids
Chemistry and Physics of Lipids, Elsevier, 2017, 207, pp.81-86. ⟨10.1016/j.chemphyslip.2017.06.010⟩
Chemistry and Physics of Lipids, 2017, 207, pp.81-86. ⟨10.1016/j.chemphyslip.2017.06.010⟩
Chemistry and Physics of Lipids, Elsevier, 2017, 207, pp.81-86. ⟨10.1016/j.chemphyslip.2017.06.010⟩
Chemistry and Physics of Lipids, 2017, 207, pp.81-86. ⟨10.1016/j.chemphyslip.2017.06.010⟩
International audience; Dendrogenin A (DDA) was recently identified as a mammalian cholesterol metabolite that displays tumor suppressor and neurostimulating properties at low doses. In breast tumors, DDA levels were found to be decreased compared to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bef4d67d42387ae88fa3aa37249c29e
https://www.hal.inserm.fr/inserm-02380602
https://www.hal.inserm.fr/inserm-02380602
Publikováno v:
Proceedings of the National Academy of Sciences. 105:20440-20445
The factors controlling memory T (Tm)-cell longevity are still poorly defined, and their identification is pivotal to the design of a vaccine conferring long-term protection against infection. Tm cells have the ability to survive in the absence of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28abf0b7154f8457f803afa918aec35
https://doi.org/10.1073/pnas.0806289106
https://doi.org/10.1073/pnas.0806289106