Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Julie Leca"'
Autor:
Richard Tomasini, Sophie Vasseur, Juan Iovanna, Mehdi Ouaissi, Jean-Baptiste Bachet, Samuel Granjeaud, Daniel Pietrasz, Thi-Thien Bui, Fabienne Guillaumond, Véronique Secq, Marie-Nöelle Lavaut, Julie Roques, Julie Leca, Jérémy Nigri, Sophie Lac, Christian Bressy
Amalysis of Akt/Stat3 signaling induction following LIF stimulation. We measured the induction of STAT3 (A) and Akt (B) phosphorylation by western blot in sNF96.2 after incubation with LIF recombinant protein. We confirmed the specificity of inductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e21777ed2cb5758a96f8a5823b3603
https://doi.org/10.1158/0008-5472.22411544
https://doi.org/10.1158/0008-5472.22411544
Autor:
Richard Tomasini, Sophie Vasseur, Juan Iovanna, Mehdi Ouaissi, Jean-Baptiste Bachet, Samuel Granjeaud, Daniel Pietrasz, Thi-Thien Bui, Fabienne Guillaumond, Véronique Secq, Marie-Nöelle Lavaut, Julie Roques, Julie Leca, Jérémy Nigri, Sophie Lac, Christian Bressy
Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive stroma and pathogenic modifications to the peripheral nervous system that elevate metastatic capacity. In this study, we show that the IL6-related stem cell–promoting factor LIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585cbdd243b8387c5a5be7d7d7f9fedd
https://doi.org/10.1158/0008-5472.c.6508250.v1
https://doi.org/10.1158/0008-5472.c.6508250.v1
Autor:
Richard Tomasini, Sophie Vasseur, Juan Iovanna, Mehdi Ouaissi, Jean-Baptiste Bachet, Samuel Granjeaud, Daniel Pietrasz, Thi-Thien Bui, Fabienne Guillaumond, Véronique Secq, Marie-Nöelle Lavaut, Julie Roques, Julie Leca, Jérémy Nigri, Sophie Lac, Christian Bressy
Supplementary methods and Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f75cc33dab542441eb1748fc918cf80
https://doi.org/10.1158/0008-5472.22411535
https://doi.org/10.1158/0008-5472.22411535
Autor:
Jerome Fortin, Ming-Feng Chiang, Cem Meydan, Jonathan Foox, Parameswaran Ramachandran, Julie Leca, François Lemonnier, Wanda Y. Li, Miki S. Gams, Takashi Sakamoto, Mandy Chu, Chantal Tobin, Eric Laugesen, Troy M. Robinson, Annick You-Ten, Daniel J. Butler, Thorsten Berger, Mark D. Minden, Ross L. Levine, Cynthia J. Guidos, Ari M. Melnick, Christopher E. Mason, Tak W. Mak
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Mutations in IDH1, IDH2 , and TET2 are recurrently observed in myeloid neoplasms. IDH1 and IDH2 encode isocitrate dehydrogenase isoforms, which normally catalyze the conversion of isocitrate to α-ketoglutarate (α-KG). Oncogenic IDH1/2 mutations con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98c0be24618f25a597313a325fc02981
https://doi.org/10.1073/pnas.2208176120
https://doi.org/10.1073/pnas.2208176120
Autor:
Jérémy Nigri, Julie Leca, Sarah-Simha Tubiana, Pascal Finetti, Fabienne Guillaumond, Sébastien Martinez, Sophie Lac, Juan L. Iovanna, Stéphane Audebert, Luc Camoin, Sophie Vasseur, François Bertucci, Richard Tomasini
Publikováno v:
Science Signaling. 15
In pancreatic ductal adenocarcinoma (PDAC), signaling from stromal cells is implicated in metastatic progression. Tumor-stroma cross-talk is often mediated through extracellular vesicles (EVs). We previously reported that EVs derived from cancer-asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7dabdfd5505a0430b07affc6d04c322
https://doi.org/10.1126/scisignal.abg8191
https://doi.org/10.1126/scisignal.abg8191
Publikováno v:
Current Opinion in Biotechnology. 68:181-185
Mutations in the genes encoding isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) are key drivers of diverse cancers, including gliomas and hematological malignancies. IDH mutations cause neomorphic enzymatic activity that results in the production of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaa085626e6f142a1306fb2b51bbc6a
https://doi.org/10.1016/j.copbio.2020.11.013
https://doi.org/10.1016/j.copbio.2020.11.013
Autor:
Jerome Fortin, Ming-Feng Chiang, Cem Meydan, Jonathan Foox, Parameswaran Ramachandran, Julie Leca, Francois Lemonnier, Wanda Y. Li, Miki S. Gams, Takashi Sakamoto, Mandy Chu, Chantal Tobin, Eric Laugesen, Troy M. Robinson, Annick You-Ten, Daniel J. Butler, Thorsten Berger, Mark D. Minden, Ross L. Levine, Cynthia J. Guidos, Ari M. Melnick, Christopher E. Mason, Tak W. Mak
Publikováno v:
Blood Cancer Discovery. 4:A16-A16
Mutations in IDH1, IDH2, and TET2 are recurrently observed in myeloid neoplasms. IDH1 and IDH2 encode isocitrate dehydrogenase isoforms, which normally catalyze the conversion of isocitrate to α-ketoglutarate (α-KG). Oncogenic IDH1/2 mutations conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c9ea68932d950dc64dba65f44beade
https://doi.org/10.1158/2643-3249.aml23-a16
https://doi.org/10.1158/2643-3249.aml23-a16
Autor:
Guangxun Gao, Zhe Wang, Tak W. Mak, Yuanlin Zhao, Yuan Yuan, Risheng Yang, Julie Leca, Jing Ye, Wenjing Zhou, Alan Tseng, Mary E. Saunders, Andrew Wakeham, Yu Gu, Liming Xiao, Feng Zhang, Lijun Zhang, Ying Yang, Wanda Y. Li, Thorsten Berger, Xing Gao, Jerome Fortin
Publikováno v:
Blood. 137:945-958
Isocitrate dehydrogenase (IDH) mutations are common genetic alterations in myeloid disorders, including acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Epigenetic changes, including abnormal histone and DNA methylation, have been imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9b063c63a1289680f22b9c039e6c18
https://doi.org/10.1182/blood.2020007075
https://doi.org/10.1182/blood.2020007075
Autor:
Victoire Gouirand, Tristan Gicquel, Evan C Lien, Emilie Jaune‐Pons, Quentin Da Costa, Pascal Finetti, Elodie Metay, Camille Duluc, Jared R Mayers, Stephane Audebert, Luc Camoin, Laurence Borge, Marion Rubis, Julie Leca, Jeremy Nigri, François Bertucci, Nelson Dusetti, Juan Lucio Iovanna, Richard Tomasini, Ghislain Bidaut, Fabienne Guillaumond, Matthew G Vander Heiden, Sophie Vasseur
Publikováno v:
EMBO Journal
EMBO Journal, 2022, ⟨10.15252/embj.2021110466⟩
The EMBO journal, vol 41, iss 9
EMBO J
EMBO Journal, 2022, ⟨10.15252/embj.2021110466⟩
The EMBO journal, vol 41, iss 9
EMBO J
Pancreatic ductal adenocarcinoma (PDA) tumor cells are deprived of oxygen and nutrients and therefore must adapt their metabolism to ensure proliferation. In some physiological states, cells rely on ketone bodies to satisfy their metabolic needs, esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402d390310382a7d2b9d332eef585cf9
https://hal-amu.archives-ouvertes.fr/hal-03623502
https://hal-amu.archives-ouvertes.fr/hal-03623502
Autor:
Julie Leca, Franҫois Lemonnier, Cem Meydan, Jonathan Foox, Samah El Ghamrasni, Diana-Laure Mboumba, Gordon S. Duncan, Jerome Fortin, Takashi Sakamoto, Chantal Tobin, Kelsey Hodgson, Jillian Haight, Logan K. Smith, Andrew J. Elia, Daniel Butler, Thorsten Berger, Laurence de Leval, Christopher E. Mason, Ari Melnick, Philippe Gaulard, Tak W. Mak
Publikováno v:
Cancer cell, vol. 41, no. 2, pp. 323-339.e10
Angioimmunoblastic T cell lymphoma (AITL) is a peripheral T cell lymphoma that originates from T follicular helper (Tfh) cells and exhibits a prominent tumor microenvironment (TME). IDH2 and TET2 mutations co-occur frequently in AITL, but their contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f98449df684ef4a2b19530d86d35a8
https://doi.org/10.1016/j.ccell.2023.01.003
https://doi.org/10.1016/j.ccell.2023.01.003