Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Julie Lajoie"'
Autor:
Kristi Loeb, Kieran A. Milner, Candice Lemaille, Brielle Martens, Derek Stein, Julie Lajoie, Souradet Y. Shaw, Anne W. Rimoin, Placide Mbala-Kingebeni, Nicole A. Hoff, Ryan S. Noyce, Keith R. Fowke, Joshua Kimani, Lyle McKinnon, Jason Kindrachuk
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 9, Pp 1944-1947 (2024)
We identified a cluster of mpox exposures among key populations in Kenya through retrospective serologic screening. We identified strong seropositivity among sex workers and gay, bisexual, and other men who have sex with men. These findings demonstra
Externí odkaz:
https://doaj.org/article/5b452ec95e4a41e6b9d57c76585c4b84
Autor:
Frideborg Bradley, Alexandra Stern, Mathias Franzén Boger, Zaynab Mousavian, Olga Dethlefsen, Vilde Kaldhusdal, Julie Lajoie, Kenneth Omollo, Sofia Bergström, Anna Månberg, Peter Nilsson, Joshua Kimani, Adam D. Burgener, Annelie Tjernlund, Christopher Sundling, Keith R. Fowke, Kristina Broliden
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThe cervicovaginal epithelial barrier is crucial for defending the female reproductive tract against sexually transmitted infections. Hormones, specifically estradiol and progesterone, along with their respective receptor expressions, play
Externí odkaz:
https://doaj.org/article/831fc87130c1463bb848812891560e77
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Invariant Natural Killer T (iNKT) cells undergo immune exhaustion during chronic activation caused by cancer and viral infections, such as HIV. Exhaustion is marked by cell dysfunction and increased expression of immune checkpoint proteins p
Externí odkaz:
https://doaj.org/article/833a43f6784741d4becad9e703bb15fa
Autor:
Gabriella Edfeldt, Vilde Kaldhusdal, Paulo Czarnewski, Frideborg Bradley, Sofia Bergström, Julie Lajoie, Jiawu Xu, Anna Månberg, Joshua Kimani, Julius Oyugi, Peter Nilsson, Annelie Tjernlund, Keith R. Fowke, Douglas S. Kwon, Kristina Broliden
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-22 (2023)
Abstract Background The majority of studies characterizing female genital tract microbiota have focused on luminal organisms, while the presence and impact of tissue-adherent ectocervical microbiota remain incompletely understood. Studies of luminal
Externí odkaz:
https://doaj.org/article/dff8081e1741453d9de5744b71287711
Publikováno v:
Frontiers in Reproductive Health, Vol 5 (2023)
Externí odkaz:
https://doaj.org/article/e1bd35731c524870896cd49fe4a5d6b4
Autor:
Frideborg Bradley, Mathias Franzén Boger, Vilde Kaldhusdal, Alexandra Åhlberg, Gabriella Edfeldt, Julie Lajoie, Sofia Bergström, Kenneth Omollo, Anastasios Damdimopoulos, Paulo Czarnewski, Anna Månberg, Julius Oyugi, Joshua Kimani, Peter Nilsson, Keith Fowke, Annelie Tjernlund, Kristina Broliden
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010494 (2022)
Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used by millions of women worldwide. However, experimental studies have associated DMPA use with genital epithelial barrier disruption and mucosal influx of human immuno
Externí odkaz:
https://doaj.org/article/b75ef1229c0244689feca2bb38e81604
Autor:
Julie Lajoie, Monika M. Kowatsch, Lucy W. Mwangi, Geneviève Boily-Larouche, Julius Oyugi, Yufei Chen, Makobu Kimani, Emmanuel A. Ho, Joshua Kimani, Keith R. Fowke
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionAcetylsalicylic acid (ASA) is a well-known and safe anti-inflammatory. At low-dose, it is prescribed to prevent secondary cardiovascular events in those with pre-existing conditions and to prevent preeclampsia. Little is known about how l
Externí odkaz:
https://doaj.org/article/f795b4bc44bb4994bf8fb9117f3c8b69
Autor:
Kenneth Omollo, Julie Lajoie, Julius Oyugi, Jocelyn M. Wessels, Dufton Mwaengo, Joshua Kimani, Charu Kaushic, Keith R. Fowke
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
BackgroundDepot Medroxyprogesterone (DMPA) is one of the most widely used contraceptives in Sub-Saharan Africa where HIV incidence is high. We explored the effect of DMPA on the activation of HIV cellular targets and inflammation as a possible mechan
Externí odkaz:
https://doaj.org/article/cda23c33cf5f45308c3f2b8cbfd2d451
Publikováno v:
AIDS Research and Therapy, Vol 14, Iss 1, Pp 1-5 (2017)
Abstract For over three decades, HIV infection has had a tremendous impact on the lives of individuals and public health. Microbicides and vaccines studies have shown that immune activation at the genital tract is a risk factor for HIV infection. Fur
Externí odkaz:
https://doaj.org/article/c3b2b33be79e431ab6f88d4248028a65
Autor:
Jocelyn M. Wessels, Julie Lajoie, Maeve I. J. Hay Cooper, Kenneth Omollo, Allison M. Felker, Danielle Vitali, Haley A. Dupont, Philip V. Nguyen, Kristen Mueller, Fatemeh Vahedi, Joshua Kimani, Julius Oyugi, Juliana Cheruiyot, John N. Mungai, Alexandre Deshiere, Michel J. Tremblay, Tony Mazzulli, Jennifer C. Stearns, Ali A. Ashkar, Keith R. Fowke, Michael G. Surette, Charu Kaushic
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
The hormonal contraceptive medroxyprogesterone acetate (MPA) is associated with increased risk of human immunodeficiency virus (HIV), via incompletely understood mechanisms. Increased diversity in the vaginal microbiota modulates genital inflammation
Externí odkaz:
https://doaj.org/article/f8e620b61ef54854b1215e331b0918aa