Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Julie Lafontaine"'
Autor:
Elena Refet-Mollof, Ouafa Najyb, Rodin Chermat, Audrey Glory, Julie Lafontaine, Philip Wong, Thomas Gervais
Publikováno v:
Cancers, Vol 13, Iss 16, p 4046 (2021)
Hypoxia is a key characteristic of the tumor microenvironment, too rarely considered during drug development due to the lack of a user-friendly method to culture naturally hypoxic 3D tumor models. In this study, we used soft lithography to engineer a
Externí odkaz:
https://doaj.org/article/6cc9701e65984e8ba92b7948f6af2793
Autor:
Julie Lafontaine, Guillaume B. Cardin, Nicolas Malaquin, Jean-Sébastien Boisvert, Francis Rodier, Philip Wong
Publikováno v:
Cancers, Vol 13, Iss 3, p 386 (2021)
Radiotherapy (RT) is a key component of cancer treatment. Most of the time, radiation is given after surgery but for soft-tissue sarcomas (STS), pre-surgical radiation is commonly utilized. However, despite improvements in RT accuracy, the rate of lo
Externí odkaz:
https://doaj.org/article/fc66b479cb6a4ab8b55416d00c8531c5
Publikováno v:
Cancers, Vol 12, Iss 2, p 348 (2020)
Cancer therapy has evolved to a more targeted approach and often involves drug combinations to achieve better response rates. Non-thermal plasma (NTP), a technology rapidly expanding its application in the medical field, is a near room temperature io
Externí odkaz:
https://doaj.org/article/4770e6f1dd3c4fefa9de6fa265c0c2dc
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31916 (2012)
In vitro, cellular immortalization and transformation define a model for multistep carcinogenesis and current ongoing challenges include the identification of specific molecular events associated with steps along this oncogenic pathway. Here, using N
Externí odkaz:
https://doaj.org/article/89776484337c408caab8a248be087080
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2543
Microfluidic technology facilitates the generation of 3D spheroids from cancer cells, a more suitable model for preclinical therapeutic studies. This system opens the possibility to test many drugs combination at a low cost. Here we describe the use
Autor:
Elena Refet-Mollof, Philip Wong, Y Kamio, Thomas Gervais, Maeva Bavoux, Julie Lafontaine, Ouafa Najyb, Jean-François Carrier, Emmanuelle Vigneux-Foley
Publikováno v:
Radiotherapy and Oncology. 157:175-181
Purpose Radioresistance, tumor microenvironment, and normal tissue toxicity from radiation limit the efficacy of radiotherapy in treating cancers. These challenges can be tackled by the discovery of new radiosensitizing and radioprotecting agents aim
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66f01bcdebc4e767dad65f30589c97d7
https://doi.org/10.1007/978-1-0716-2553-8_2
https://doi.org/10.1007/978-1-0716-2553-8_2
Comparison of Three Radio-Frequency Discharge Modes on the Treatment of Breast Cancer Cells in Vitro
Publikováno v:
IEEE Transactions on Radiation and Plasma Medical Sciences. 4:644-654
Non-thermal plasmas (NTPs) are known for their ability to induce thermal-free cytotoxic effects on cancer cells. However, as the variety of NTP devices increases, comparison of their cytotoxic effect becomes increasingly essential. In this work, we c
Autor:
Elena Refet-Mollof, Ouafa Najyb, Rodin Chermat, Audrey Glory, Julie Lafontaine, Philip Wong, Thomas Gervais
Publikováno v:
Clinical Cancer Research. 28:B005-B005
Context: Hypoxia is found in at least 47% of soft-tissue sarcoma (STS) patients and is known to be a major contributor to treatment resistance, metastasis progression and associated with poor prognosis. Indeed, expression of hypoxic proteins (HIF1-α
Autor:
Jean-François Carrier, Bishnubrata Patra, Philip Wong, Mohsen Ahanj, Karim Zerouali, Julie Lafontaine, Maeva Bavoux, Audrey Glory, Thomas Gervais
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Radiotherapy (RT) and chemotherapy (CT) are the major therapeutics to treat cancer patients. Conventional in vitro 2D models are insufficient to study the combined effects of RT and CT towards optimized dose selection or drug screening. Soft-tissue s