Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Julie Lacroix‐Labonté"'
Publikováno v:
Ribozymes. :463-485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9cbea0019796e754db22b28dd273af5
https://doi.org/10.1002/9783527814527.ch17
https://doi.org/10.1002/9783527814527.ch17
Publikováno v:
Nucleic Acids Research
Investigating the dynamics of structural elements in functional RNAs is important to better understand their mechanism and for engineering RNAs with novel functions. Previously, we performed rational engineering studies with the Varkud satellite (VS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ad4f94b6260167a8c7f2f5ebbf6590
https://pubmed.ncbi.nlm.nih.gov/30993347
https://pubmed.ncbi.nlm.nih.gov/30993347
Publikováno v:
Nucleic Acids Research
The Neurospora VS ribozyme is a catalytic RNA that has the unique ability to specifically recognize and cleave a stem-loop substrate through formation of a highly stable kissing-loop interaction (KLI). In order to explore the engineering potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6f378ad52d0834abc86b637a2c3b55
https://doi.org/10.1093/nar/gkw401
https://doi.org/10.1093/nar/gkw401
Publikováno v:
Nucleic Acids Research
Compensatory mutations in RNA are generally regarded as those that maintain base pairing, and their identification forms the basis of phylogenetic predictions of RNA secondary structure. However, other types of compensatory mutations can provide high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706b84e87237263cf72e44af355d3164
http://europepmc.org/articles/PMC3299992
http://europepmc.org/articles/PMC3299992
Autor:
Véronique Lisi, Patricia Bouchard, Pascale Legault, Philipe Lampron, Geneviève Desjardins, François Major, Julie Lacroix-Labonté, Sébastien Lemieux
Publikováno v:
RNA (New York, N.Y.). 14(4)
Substrate recognition by the VS ribozyme involves a magnesium-dependent loop/loop interaction between the SLI substrate and the SLV hairpin from the catalytic domain. Recent NMR studies of SLV demonstrated that magnesium ions stabilize a U-turn loop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0459b938f627c7b3717f0894d94dbe16
https://pubmed.ncbi.nlm.nih.gov/18314503
https://pubmed.ncbi.nlm.nih.gov/18314503