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Publikováno v:
Angewandte Chemie. 135
Accurate prediction of the sensitivity properties of high-energy materials (HEMs) and the study of their decomposition mechanisms are two major focuses within energetics research. Due to the hazards associated with the synthesis and handling of energ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54d6aa996b660dfa483fcd607a38ad6
https://doi.org/10.26434/chemrxiv-2021-16f6w-v2
https://doi.org/10.26434/chemrxiv-2021-16f6w-v2
Publikováno v:
Organic Synth
[Image: see text]
Autor:
Frances H. Arnold, Bruce J. Wittmann, Julie L. Hofstra, Anders M. Knight, S. B. Jennifer Kan, Sarah E. Reisman
Publikováno v:
ACS Catal
While biocatalysis is increasingly incorporated into drug development pipelines, it is less commonly used in the early stages of drug discovery. By engineering a protein to produce a chiral motif with a derivatizable functional handle, biocatalysts c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d341980e44cfb5658215331dc69448c
https://resolver.caltech.edu/CaltechAUTHORS:20200608-115355402
https://resolver.caltech.edu/CaltechAUTHORS:20200608-115355402
Publikováno v:
Organic Letters. 19:2150-2153
An enantioselective Ni-catalyzed cross-coupling of N-hydroxyphthalimide esters with vinyl bromides is reported. The reaction proceeds under mild conditions and uses tetrakis(N,N-dimethylamino)ethylene as a terminal organic reductant. Good functional
Publikováno v:
Angew Chem Int Ed Engl
A Ni‐catalyzed halogenation of enol triflates was developed and it enables the synthesis of a broad range of alkenyl iodides, bromides, and chlorides under mild reaction conditions. The reaction utilizes inexpensive, bench‐stable Ni(OAc)_2⋅4 H_
An asymmetric Ni-catalyzed reductive cross-coupling has been developed to prepare enantioenriched allylic silanes. This enantioselective reductive alkenylation proceeds under mild conditions and exhibits good functional group tolerance. The chiral al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17bac214ca5df651b1cd985618cfe83
https://resolver.caltech.edu/CaltechAUTHORS:20171205-112031343
https://resolver.caltech.edu/CaltechAUTHORS:20171205-112031343
Autor:
H. J. Peter de Lijser, Brittany R. Grassbaugh, Nicholas R. Armada, Quan M. Tran, Julie L. Hofstra
Publikováno v:
ChemInform. 46
The photocyclization of oxime ethers in the presence of 9,10-dicyanoanthracene as the sensitizer affords phenanthridines without any nitrile byproducts.
Autor:
H. J. Peter de Lijser, Brittany R. Grassbaugh, Quan M. Tran, Julie L. Hofstra, Nicholas R. Armada
Publikováno v:
The Journal of organic chemistry. 80(1)
A series of 2′-arylbenzaldehyde oxime ethers were synthesized and shown to generate the corresponding phenanthridines upon irradiation in the presence of 9,10-dicyanoanthracene in acetonitrile. Mechanistic studies suggest that the oxidative cycliza