Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites

Autor: Paul W. Denny, Ehmke Pohl, Amjed Qays Al-Qaisi, Morten K. Grøftehauge, Louise E. Bird, Hosam Shams-Eldin, Julie K. Thye, Steven Pratt, Robert H. Dods, Jackie A. Mosely, John G. Mina, Ralph T. Schwarz

Publikováno v: The Journal of Biological Chemistry
Journal of biological chemistry, 2017, Vol.292(29), pp.12208-12219 [Peer Reviewed Journal]

Toxoplasma gondii is an obligate, intracellular eukaryotic apicomplexan protozoan parasite that can cause fetal damage and abortion in both animals and humans. Sphingolipids are essential and ubiquitous components of eukaryotic membranes that are bot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7d2f9725c0290d3ed912353f3931f1
https://doi.org/10.1074/jbc.m117.792374