Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Julie K Schwarz"'
Autor:
Ramachandran Rashmi, Carl DeSelm, Cynthia Helms, Anne Bowcock, Buck E Rogers, Janet L Rader, Perry W Grigsby, Julie K Schwarz
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e92948 (2014)
PI3K/AKT pathway alterations are associated with incomplete response to chemoradiation in human cervical cancer. This study was performed to test for mutations in the PI3K pathway and to evaluate the effects of AKT inhibitors on glucose uptake and ce
Externí odkaz:
https://doaj.org/article/50dc0cb2a0904a2f94fc4762fddc626c
Autor:
Liyun Chen, Victoria Shi, Songyan Wang, Lulu Sun, Rebecca Freeman, Jasmine Yang, Matthew J. Inkman, Subhajit Ghosh, Fiona Ruiz, Kay Jayachandran, Yi Huang, Jingqin Luo, Jin Zhang, Pippa Cosper, Clifford J. Luke, Catherine S. Spina, Perry W. Grigsby, Julie K. Schwarz, Stephanie Markovina
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 15 (2023)
Patients with cancer who have high serum levels of squamous cell carcinoma antigen 1 (SCCA1, now referred to as SERPINB3) commonly experience treatment resistance and have a poor prognosis. Despite being a clinical biomarker, the modulation of SERPIN
Externí odkaz:
https://doaj.org/article/a09211f5a61947efb47a9d24712b29ab
Autor:
Songyan Wang, Cliff J. Luke, Stephen C. Pak, Victoria Shi, Liyun Chen, Jonathan Moore, Arlise P. Andress, Kay Jayachandran, Jin Zhang, Yi Huang, Marina Platik, Anthony A. Apicelli, Julie K. Schwarz, Perry W. Grigsby, Gary A. Silverman, Stephanie Markovina
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Wang et al. demonstrate the cytoprotective role of SERPINB3 against radiation-induced necrosis, showing that cells lacking SERPINB3 protein both in culture and in mice are more sensitive to radiation and cisplatin-induced cell death. The authors also
Externí odkaz:
https://doaj.org/article/125c4804dd504bf099b34a577102b07a
Autor:
David M. Zhang, Rachita Navara, Tiankai Yin, Jeffrey Szymanski, Uri Goldsztejn, Camryn Kenkel, Adam Lang, Cedric Mpoy, Catherine E. Lipovsky, Yun Qiao, Stephanie Hicks, Gang Li, Kaitlin M. S. Moore, Carmen Bergom, Buck E. Rogers, Clifford G. Robinson, Phillip S. Cuculich, Julie K. Schwarz, Stacey L. Rentschler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Noninvasive cardiac radiotherapy may effectively manage ventricular tachycardia in refractory patients, but its radiobiologic mechanisms of action are unclear. Here, the authors show that photon radiation durably and favourably reprograms cardiac con
Externí odkaz:
https://doaj.org/article/b87d769fbd7248d484a32dad47327e5a
Autor:
Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Patient-derived xenograft models (PDX) have been extensively used to study the molecular and clinical features of cancers. Here the authors present a cohort of 536 PDX models from 25 cancers, as well as their genomic and evolutionary profiles and the
Externí odkaz:
https://doaj.org/article/e6286532f9bc487a87943a142621d7a3
Autor:
Fiona J. Ruiz, Matthew Inkman, Ramachandran Rashmi, Naoshad Muhammad, Nishanth Gabriel, Christopher A. Miller, Michael D. McLellan, Michael Goldstein, Stephanie Markovina, Perry W. Grigsby, Jin Zhang, Julie K. Schwarz
Publikováno v:
JCI Insight, Vol 6, Iss 16 (2021)
Persistent HPV infection is causative for the majority of cervical cancer cases; however, current guidelines do not require HPV testing for newly diagnosed cervical cancer. Using an institutional cohort of 88 patients with cervical cancer treated uni
Externí odkaz:
https://doaj.org/article/561372e4f6984d4b841f454f88d97ab7
Autor:
H. Michael Gach, PhD, Stacie L. Mackey, AAS, Sarah E. Hausman, BS, Danielle R. Jackson, BS, Tammie L. Benzinger, MD, PhD, Lauren Henke, MD, Lindsay A. Murphy, BS, Jamie L. Fluchel, BS, Bin Cai, PhD, Jacqueline E. Zoberi, PhD, Jose Garcia-Ramirez, MS, Sasa Mutic, PhD, Julie K. Schwarz, MD, PhD
Publikováno v:
Radiology Case Reports, Vol 14, Iss 5, Pp 634-638 (2019)
Obese patients constitute 40% of the adult population. MRIs of obese patients are typically challenging because of the effects of a large field of view on image quality and the increased risk of thermal burns from contact with the bore. In this case
Externí odkaz:
https://doaj.org/article/7b602a704bc84709a081826ae983646f
Autor:
Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/395184e65c5746b0adbbaf31dc3c4cc4
Autor:
John M. Floberg, Kathryn J. Fowler, Dominique Fuser, Todd A. DeWees, Farrokh Dehdashti, Barry A. Siegel, Richard L. Wahl, Julie K. Schwarz, Perry W. Grigsby
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background This study investigated the spatial relationship of 2-deoxy-2-[18F]-fluoro-D-glucose positron emission tomography ([18F]FDG-PET) standardized uptake values (SUVs) and apparent diffusion coefficients (ADCs) derived from magnetic re
Externí odkaz:
https://doaj.org/article/7beef5b12a2f40bd87d74ca80611de62
Autor:
Stephanie Markovina, Katharine A. Rendle, Alexander C. Cohen, Lindsay M. Kuroki, Surbhi Grover, Julie K. Schwarz
Publikováno v:
Cancer
Cervical cancer is associated with profound socioeconomic and racial disparities in incidence, mortality, morbidity, and years of life lost. The last standard-of-care treatment innovation for locally advanced cervical cancer occurred in 1999, when ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2023bc3667758e3dbc0f2862127b49
https://doi.org/10.1002/cncr.34485
https://doi.org/10.1002/cncr.34485