Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Julie K Freed"'
Publikováno v:
BMC Anesthesiology, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Hypotension that is resistant to phenylephrine is a complication that occurs in anesthetized patients treated with angiotensin converting enzyme (ACE) inhibitors. We tested the hypothesis that Ang 1–7 and the endothelial Mas rec
Externí odkaz:
https://doaj.org/article/b61412f3162d48e48ffdf5f5117c8ff6
Autor:
Katie E. Cohen, Boran Katunaric, Mary E. Schulz, Gopika SenthilKumar, Micaela S. Young, James E. Mace, Julie K. Freed
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Chronic administration of exogenous adiponectin restores nitric oxide (NO) as the mediator of flow-induced dilation (FID) in arterioles collected from patients with coronary artery disease (CAD). Here we hypothesize that this effect as well as NO sig
Externí odkaz:
https://doaj.org/article/9067a2811db04420b4fcbd330fe29e94
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(10)
Background: Preclinical studies suggest that S1P (sphingosine-1-phosphate) influences blood pressure regulation primarily through NO-induced vasodilation. Because microvascular tone significantly contributes to mean arterial pressure, the mechanism o
Autor:
Gopika SenthilKumar, Boran Katunaric, Henry Bordas-Murphy, Micaela Young, Erin L. Doren, Mary E. Schulz, Michael E. Widlansky, Julie K. Freed
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H330-H337
Despite data showing that estrogen is vasculoprotective in large conduit arteries, hormone therapy (HT) during menopause has not proven to mitigate cardiovascular disease (CVD) risk. Estrogen exposure through prolonged oral contraceptive use and gend
Autor:
Jayshil J. Patel, Rodney Willoughby, Jennifer Peterson, Thomas Carver, James Zelten, Adrienne Markiewicz, Kaitlin Spiegelhoff, Lauren A. Hipp, Bethany Canales, Aniko Szabo, Daren K. Heyland, Christian Stoppe, Jacek Zielonka, Julie K. Freed
Publikováno v:
Chest. 163:303-312
Autor:
Gopika SenthilKumar, Cristhian A. Gutierrez-Huerta, Julie K. Freed, Andreas M. Beyer, Ibra S. Fancher, Amanda Jo LeBlanc
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H1167-H1175
Microvascular disease plays a critical role in systemic end-organ dysfunction, and treatment of microvascular pathologies may greatly reduce cardiovascular morbidity and mortality. The Call for Papers collection: New Developments in Translational Mic
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 17 (2019)
Background Elevated levels of ceramide, a sphingolipid known to cause a transition from nitric oxide (NO)– to hydrogen peroxide–dependent flow‐induced dilation (FID) in human arterioles, correlate with adverse cardiac events. However, elevation
Externí odkaz:
https://doaj.org/article/42ccd2f7aba3410a8d6529bb53450bdc
Publikováno v:
Am J Physiol Heart Circ Physiol
Cardiovascular disease risk increases with age regardless of sex. Some of this risk is attributable to alterations in natural hormones throughout the life span. The quintessential example of this being the dramatic increase in cardiovascular disease
Autor:
Brent T. Boettcher, Timothy J. Lazicki, George J. Crystal, Julie K. Freed, Justin N. Tawil, David A. Izquierdo, Paul S. Pagel
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 35:1839-1859
Almost three-quarters of all heart failure patients who are older than 65 have heart failure with preserved ejection fraction (HFpEF). The proportion and hospitalization rate of patients with HFpEF are increasing steadily relative to patients in whom
Publikováno v:
International journal of surgery case reports. 98
Catecholamine-resistant vasoplegia is a potentially devastating complication during liver transplantation. Hydroxocobalamin has emerged as a treatment for vasoplegia associated with cardiac surgery, liver transplantation, and septic shock.We performe