Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Julie Jodoin"'
Autor:
Julie Jodoin, Micheal Misiewicz, Priya Makhijani, Paresa N Giannopoulos, Jennifer Hammond, Cynthia G Goodyer, Andréa C LeBlanc
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6647 (2009)
Previously, we have shown the loss of anti-Bax function in Creutzfeldt Jakob disease (CJD)-associated prion protein (PrP) mutants that are unable to generate cytosolic PrP (CyPrP). To determine if the anti-Bax function of PrP modulates the manifestat
Externí odkaz:
https://doaj.org/article/7be3f3cb33d9477eb0482d8a8ac24e20
Autor:
Mary Jane Johnson, Marianne Ahlgren, Betty R. Vohr, Julie Jodoin-Krauzyk, Richard Tucker, LSt Pierre, Deborah Topol
Publikováno v:
Journal of Perinatology. 31:274-280
The aim of this study was to determine the expressive vocabulary of children with hearing loss (HL) enrolled in early intervention (EI) ≤ 3 vs3 months in the first 24 months and to compare with hearing controls. It was hypothesized that the number
Autor:
Stephanie A. Booth, Paresa N. Giannopoulos, Catherine Robertson, Hemant Paudel, Julie Jodoin, Andréa C. LeBlanc
Publikováno v:
Journal of Neuroscience. 29:8743-8751
The cause of the conformational change of normal cellular prion protein (PrP) into its disease-associated form is unknown. Posttranslational modifications, such as glycosylation, acetylation, S-nitrosylation, and phosphorylation, are known to induce
Autor:
Marianne Ahlgren, Richard Tucker, Julie Jodoin-Krauzyk, Deborah Topol, Betty R. Vohr, Mary Jane Johnson
Publikováno v:
Pediatrics. 122:535-544
OBJECTIVES. The objectives of this study were to determine the early language outcomes of children with mild to profound hearing loss, compared with hearing control children, at 12 to 16 months of age and to examine the effects of “very early” en
Publikováno v:
The Journal of Neuroscience. 27:5081-5091
Prion protein (PrP) inhibits the activation of proapoptotic Bax in primary human neurons and MCF-7 cells. Because neuronal apoptosis occurs in human prion diseases, here we examine the anti-Bax function of familial PrP mutants. All Creutzfeldt-Jakob
Autor:
Xavier Roucou, Andréa C. LeBlanc, Julie Jodoin, Cynthia G. Goodyer, Paresa N. Giannopoulos, Yan Zhang
Publikováno v:
Cell Death & Differentiation. 12:783-795
Prion protein (PrP) prevents Bcl-2-associated protein X (Bax)-mediated cell death, but the step at which PrP inhibits is not known. We first show that PrP is very specific for Bax and cannot prevent Bak (Bcl-2 antagonist killer 1)-, tBid-, staurospor
Autor:
Sandra Turcotte, Anthony Regina, Richard Béliveau, Michel Demeule, Mathieu Brossard, Julie Jodoin
Publikováno v:
Biochemical and Biophysical Research Communications. 324:937-945
The organosulfur compounds (OSCs), present in garlic, are studied for their protective effect against human cancers. P-glycoprotein (P-gp) and multidrug resistance protein 2 (Mrp2) are two transporters involved in the defense of cells and in the deve
Autor:
Laurence Fenart, Julie Jodoin, Roméo Cecchelli, Richard Béliveau, Michel Demeule, Kenneth J. Linton, Christopher F. Higgins, Sarah Farmer
Publikováno v:
Journal of Neurochemistry. 87:1010-1023
P-glycoprotein (P-gp), an adenosine triphosphate (ATP)-binding cassette transporter which acts as a drug efflux pump, is highly expressed at the blood-brain barrier (BBB) where it plays an important role in brain protection. Recently, P-gp has been r
Autor:
Richard R. Desrosiers, Delara Karkan, Tran Nguyen, Julie Lanthier, Yanick Bertrand, Wilfred A. Jefferies, Michel Demeule, Sam Tsai, Roméo Cecchelli, Claude Dagenais, Richard Béliveau, Julie Poirier, Laurence Fenart, Reinhard Gabathuler, Malcolm L. Kennard, Julie Jodoin
Publikováno v:
Journal of Neurochemistry. 83:924-933
The blood-brain barrier (BBB) performs a neuroprotective function by tightly controlling access to the brain; consequently it also impedes access of proteins as well as pharmacological agents to cerebral tissues. We demonstrate here that recombinant
Autor:
Denis Gingras, Jonathan Michaud-Levesque, Julie Jodoin, Sylvie Lamy, Richard Béliveau, Dominique Boivin, Borhane Annabi, Yanick Bertrand, Michel Demeule
Publikováno v:
Current Medicinal Chemistry-Anti-Cancer Agents. 2:441-463
The concept of cancer prevention by use of naturally occuring substances that could be included in the diet is under investigation as a practical approach towards reducing cancer incidence, and therefore the mortality and morbidity associated with th