Výsledky vyhledávání - "Julie Innocent"

Identification of five novel modifier loci of ApcMin harbored in the BXH14 recombinant inbred strain

Autor: Julie Innocent, Rayneisha Watson, Stephanie C. Nnadi, Arthur M. Buchberg, Gregory E. Gonye, Linda D. Siracusa

Publikováno v: Carcinogenesis. 33:1589-1597

Every year thousands of people in the USA are diagnosed with small intestine and colorectal cancers (CRC). Although environmental factors affect disease etiology, uncovering underlying genetic factors is imperative for risk assessment and developing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985709bb1ccc32809f20fa40e33d7cae
https://doi.org/10.1093/carcin/bgs185

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Remote genomic consultation to support uptake of a multi-gene genomic tumor panel (MGTP) by community oncologists (COs): Results of a pilot study

Autor: Elizabeth Handorf, Yana Chertock, Julie Innocent, Mary B. Daly, Yu-Ning Wong, Michael J. Hall, John M. Kaczmar

Publikováno v: Journal of Clinical Oncology. 35:1587-1587

1587 Background: MGTP use in routine cancer (CA) care is likely to increase w/lower costs for NGS-based testing and growing numbers of actionable targets coupled with targeted therapeutics. Early MGPT uptake has been slow among community oncologists

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c88e1d6a0e8c30a2a9b769092614a19c
https://doi.org/10.1200/jco.2017.35.15_suppl.1587

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Patient interest and willingness-to-pay (WTP) out-of-pocket (OOP) for comprehensive tumor genetic profiling (CGP)

Autor: Elizabeth Handorf, Yana Chertock, Yu-Ning Wong, Julie Innocent, Jennifer M. Matro, Mary B. Daly, Michael J. Hall

Publikováno v: Journal of Clinical Oncology. 33:1545-1545

1545 Background: CGP via multiplex gene panels has emerged as a novel technology to identify mutations in pathologically relevant cancer genes for therapy targeting. While CGP is anticipated to alt...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4739e1f2d5807c681c52f27e079c2875
https://doi.org/10.1200/jco.2015.33.15_suppl.1545

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Reduced PD-1/PD-L1 expression in KRAS-mutant versus wild-type microsatellite instable (MSI-H) colorectal cancer (CRC) and association of wnt pathway corepressor TLE-3

Autor: Aarti K. Bhatia, Raji Shameem, Julie Innocent, Sergei I. Grivennikov, Namrata Vijayvergia, Zoran Gatalica, Wafik S. El-Deiry, Joanne Xiu

Publikováno v: Journal of Clinical Oncology. 33:3611-3611

3611 Background: MSI-H CRC comprises ~15% of CRC & has higher PD-1 & PD-L1 (P(+)) expression in CD4+ lymphocytes & tumor cells, respectively, compared to non-MSI-H CRC. Immune-checkpoint inhibitor ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3169892cc10950ffb7dd41f00053a8e6
https://doi.org/10.1200/jco.2015.33.15_suppl.3611

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Bilateral granulosa cell tumors: a novel malignant manifestation of multiple endocrine neoplasia 1 syndrome found in a patient with a rare menin in-frame deletion

Autor: Walter J. Scott, Hong Wu, Hossein Borghaei, Julie Innocent, Aruna Turaka, Colleen Veloski, Mary B. Daly, John P. Hoffman, John A. Ridge, Michael J. Hall, Christina Rybak

Publikováno v: The Application of Clinical Genetics

Introduction Multiple endocrine neoplasia 1 (MEN1) is a cancer syndrome resulting from mutations of the MEN1 gene. The syndrome is characterized by neoplasia of the parathyroid and pituitary glands, and malignant tumors of the endocrine pancreas. Oth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99293506db56af9d71c850fd4ae485d9
https://doi.org/10.2147/tacg.s72223

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Academic (AO) and community (CO) oncologists’ knowledge, understanding, and preparedness for clinical next-generation sequencing genomic testing (NGSGT)

Autor: Carolyn Y. Fang, Yana Chertock, Mary B. Daly, Kim Rainey, Jennifer M. Matro, Steven J. Cohen, Yu-Ning Wong, Michael J. Hall, Karen Ruth, Patrick McKay Boland, Julie Innocent

Publikováno v: Journal of Clinical Oncology. 32:e17635-e17635

e17635 Background: The potential to one day tailor all cancer treatments to a tumor’s genomic profile is an emerging reality due to the commercial availability of NGSGT. While healthcare providers ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c975637b76dd005fb3dc3bb05aee9e92
https://doi.org/10.1200/jco.2014.32.15_suppl.e17635

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Synthetic models for the zinc sites in the methionine synthases

Autor: Louise M. Liable-Sands, Charles G. Riordan, Show-Jen Chiou, Julie Innocent, Kin-Chung Lam, Arnold L. Rheingold

Publikováno v: Inorganic chemistry. 39(19)

The syntheses and molecular structures of a series of tetrahedral zinc complexes designed to model the active sites in Escherichia coli methionine synthases are reported. [PhTttBu]ZnBr (PhTttBu = phenyltris((tert-butylthio)-methyl)borate) was prepare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9299674b6b96ddab6563410f12e8b54c
https://pubmed.ncbi.nlm.nih.gov/11196931

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