Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julie I Jay"'
Autor:
Margie H Smith, Julie I Jay, David E Tast, Ryan R Williams, Patrick Brunhoeber, Heather L Free, Michael Sugarman
Publikováno v:
Histopathology. 62:563-577
Aims A recent study examining the specificity of human epidermal growth factor receptor (HER) 2 pharmacodiagnostic antibodies demonstrated that CB11 and 4B5 stain both HER2-transfected and HER4-transfected cell lines. However, there has been no evide
Autor:
Shetha Shukair, Alamelu Mahalingam, Julie I. Jay, Michael D. McRaven, Lisa C. Rohan, Kristofer Langheinrich, Patrick F. Kiser, Thomas J. Hope, Betsy C. Herold
Publikováno v:
Biomaterials. 32:8343-8355
In conjunction with the routine role of delivering the active ingredient, carefully designed drug delivery vehicles can also provide ancillary functions that augment the overall efficacy of the system. Inspired by the ability of the cervicovaginal mu
Autor:
Julie I. Jay, Hyder A. Aliyar, Meredith R. Clark, Patrick F. Kiser, Karen M. Watson, Chang Won Lee, Robert W. Buckheit, Russell J. Stewart, Kavita M. Gupta
Publikováno v:
International Journal of Pharmaceutics. 413:10-18
This paper describes the design, construction and characterization of the first anti-HIV drug delivery system that is triggered to release its contents in the presence of human semen. Microgel particles were synthesized with a crosslinker containing
Autor:
David G. Myszka, Kris Langheinrich, Julie I. Jay, Patrick F. Kiser, Bonnie E. Lai, Alamelu Mahalingam, David F. Katz
Publikováno v:
Molecular Pharmaceutics. 7:116-129
Microbicides are women-controlled prophylactics for sexually transmitted infections. The most important class of microbicides target HIV-1 and contain antiviral agents formulated for topical vaginal delivery. Identification of new viral entry inhibit
Autor:
Shetha Shukair, Kristofer Langheinrich, Thomas J. Hope, Gianguido C. Cianci, Todd J. Johnson, Julie I. Jay, Meredith R. Clark, Melissa C. Hanson, Patrick F. Kiser
Publikováno v:
Advanced Functional Materials. 19:2969-2977
Materials that respond to physiological stimuli are important in developing advanced biomaterials for modern therapies. The reversibility of covalent-crosslinks formed by phenylboronate (PBA) and salicylhydroxamate (SHA) has been exploited to provide
Publikováno v:
Crystal Growth & Design. 1:501-507
2-Mercapto-1-methylimidazole (mmim) forms complexes with organic iodides, 1,4-diiodotetrafluorobenzene (p-F4DIB), tetraiodoethylene (TIE), and 1,2-diiodotetrafluorobenzene (o-F4DIB), in which there are remarkably similar N−H···S hydrogen bonding
Publikováno v:
Antiviral Research. 82:A63-A64
Autor:
Michael Sugarman, Julie I Jay, Ryan R Williams, David E Tast, Patrick Brunhoeber, Margie H Smith, Heather L Free
Publikováno v:
Journal of Clinical Oncology. 30:16-16
16 Background: The ability of pharmacodiagnostic antibodies to specifically detect their target antigen is essential to their performance. Non-clinical protein based models for specificity of two human epidermal growth factor 2 (HER2) pharmacodiagnos
Autor:
Alamelu Mahalingam, Melissa C. Hanson, Julie I. Jay, Kristofer Langheinrich, Patrick F. Kiser
Publikováno v:
Soft Matter. 7:5826
A pH responsive system capable of forming a self-healing transient network across the pH 4.5 to 7.5 range is developed by increasing the ratio of phenylboronic acid (PBA) moieties to salicylhydroxamic acid (SHA) moieties incorporated in poly[N-2-hydr