Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julie Hunault"'
Autor:
J.Y. Douillard, Christine Saluzzo, Stéphane Guillarme, Gilles Dujardin, Séverine Marionneau-Lambot, Jézabel Rocher, Jacques Le Pendu, Jean-Yves Le Questel, Michel Evain, Jacques Lebreton, Jean-Cédric Frison, Didier Dubreuil, Mette Diswall, Muriel Pipelier, Thibauld Oullier, Denis Jacquemin, Jérôme Graton, Julie Hunault, Virginie Blot
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (3), pp.1227-1241. ⟨10.1021/jm201368m⟩
Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (3), pp.1227-1241. ⟨10.1021/jm201368m⟩
We propose here the synthesis and biological evaluation of 3,4-dideoxy-GalCer derivatives. The absence of the 3- and 4-hydroxyls on the sphingoid base is combined with the introduction of mono or difluoro substituent at C3 (analogues 8 and 9, respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f556f1ec2e2dbc55f525dbb4debb45f0
https://doi.org/10.1021/jm201368m
https://doi.org/10.1021/jm201368m
Autor:
Julie Hunault, Adjou Ané, Virginie Silvestre, Nathalie Bourgougnon, Jacques Lebreton, Raymond F. Schinazi, Muriel Pipelier, Jong-Hyun Cho, Mervi Detorio, Valérie Fargeas, Virginie Blot, Didier Dubreuil, Wilfried Hatton, Maxim Egorov, Christophe Len, Tami R. McBrayer
Publikováno v:
European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, 36, pp.7390-7399
European J Org Chem
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, 36, pp.7390-7399
European J Org Chem
A set of pyrimidine nucleosides fused with a 4′-C,3′-O-propylene bridge was successfully synthesised in 12 steps from 1,2:5,6-di-O-isopropylidene-α-d-glucofuranose, an inexpensive starting material, based on a ring-closing metathesis (RCM) react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c86db0406f01a9c67f0953d7937b8d
https://doi.org/10.1002/ejoc.201100859
https://doi.org/10.1002/ejoc.201100859
Autor:
Virginie Blot, Julie Hunault, Jacques Le Pendu, Didier Dubreuil, Anne-Laure Turcot-Dubois, Laurent Micouin, Marc Bonneville, Vivien Lacone, Thomas Lecourt, Séverine Marionneau, Jézabelle Rocher, Muriel Pipelier, Monique Clément, J.Y. Douillard
Publikováno v:
Journal of Medicinal Chemistry. 52:4960-4963
4-Deoxy-alpha-GalCer analogues are considered weaker agonists than KRN7000 for the stimulation of human iNKT cells, but this remains strongly debated. In this work, we described a strategy toward 4-deoxy-alpha-GalCers with, as a key step, a metathesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b422cb212bc920bca95b8dabbd45ffaa
https://doi.org/10.1021/jm900290r
https://doi.org/10.1021/jm900290r
Autor:
Vivien Lacône, Julie Hunault, Muriel Pipelier, Virginie Blot, Thomas Lecourt, Jézabelle Rocher, Anne-Laure Turcot-Dubois, Séverine Marionneau, Jean-Yves Douillard, Monique Clément, Jacques Le Pendu, Marc Bonneville, Laurent Micouin, Didier Dubreuil
Publikováno v:
Journal of Medicinal Chemistry; Aug2009, Vol. 52 Issue 15, p4960-4963, 4p