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pro vyhledávání: '"Julie Hjelmhaug"'
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2015:1-9
The cystine/glutamate exchanger (systemxc-) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, systemxc-can potentially cause excitotoxicity. However, through providing cystine to the cell, it regulates
Autor:
Doug Lobner, Jon M. Resch, SuJean Choi, David A. Baker, Julie Hjelmhaug, XiaoQian Liu, Rebecca Albano
Publikováno v:
Synapse. 68:604-612
In the central nervous system, cystine import in exchange for glutamate through system xc- is critical for the production of the antioxidant glutathione by astrocytes, as well as the maintenance of extracellular glutamate. Therefore, regulation of sy
Publikováno v:
Alzheimer's & Dementia. 15:P958-P958
Publikováno v:
Journal of Endodontics. 36:1149-1153
Introduction The objective was to determine the effects of growth factor treatment on dental pulp cell sensitivity to toxicity of 2 composite restoration materials, Flow Line and Durafill VS, and a calcium hydroxide pulp capping material, Dycal. Meth
Publikováno v:
NeuroToxicology. 30:47-51
Chelation therapy for the treatment of acute, high dose exposure to heavy metals is accepted medical practice. However, a much wider use of metal chelators is by alternative health practitioners for so called "chelation therapy". Given this widesprea
Publikováno v:
Neurochemical Research. 28:749-756
Neurotrophic factors have been shown to potentiate necrotic neuronal death in cortical cultures. In this study we characterized the death induced by various oxidative insults and tested the effects of neurotrophic factors on that death. Treatment wit
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2015 (2015)
Oxidative Medicine and Cellular Longevity, Vol 2015 (2015)
The cystine/glutamate exchanger (system xc (-)) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, system xc (-) can potentially cause excitotoxicity. However, through providing cystine to the cell, it
Publikováno v:
Neuroscience. 166(3)
The main action of organophosphorous insecticides is generally believed to be the inhibition of acetylcholinesterase (AChE). However, these compounds also inhibit many other enzymes, any of which may play a role in their toxicity. We tested the neuro
Publikováno v:
Neurochemical research. 28(5)
Neurotrophic factors have been shown to potentiate necrotic neuronal death in cortical cultures. In this study we characterized the death induced by various oxidative insults and tested the effects of neurotrophic factors on that death. Treatment wit
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 25:S440-S440
Estrogen has been shown to be neuroprotective both in vitro and in vivo. However, the concentration of estrogen used has often been non-physiological. Therefore, we characterized the effects of a wide range of estrogen (17beta-estradiol) concentratio