Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Julie Giraud"'
Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor
Autor:
Lornella Seeneevassen, Anissa Zaafour, Elodie Sifré, Coralie Genevois, Tra Ly Nguyen, Yasmine Pobiedonoscew, Alban Giese, Jérôme Guignard, Camille Tiffon, Benoit Rousseau, Anne-Aurélie Raymond, Geneviève Belleannée, Hélène Boeuf, Caroline Gronnier, Océane C. B. Martin, Julie Giraud, Philippe Lehours, Pierre Dubus, Christine Varon
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Gastric cancer’s (GC) bad prognosis is usually associated with metastatic spread. Invasive cancer stem cells (CSC) are considered to be the seed of GC metastasis and not all CSCs are able to initiate metastasis. Targeting these aggressive
Externí odkaz:
https://doaj.org/article/f3c91b91bd3d4c56a8a9fbd0497898b6
Autor:
Julie Giraud, Domitille Chalopin, Eloïse Ramel, Thomas Boyer, Atika Zouine, Marie-Alix Derieppe, Nicolas Larmonier, Olivier Adotevi, Brigitte Le Bail, Jean-Frédéric Blanc, Christophe Laurent, Laurence Chiche, Marc Derive, Macha Nikolski, Maya Saleh
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113773- (2024)
Summary: Hepatocellular carcinoma (HCC) is an inflammation-associated cancer arising from viral or non-viral etiologies including steatotic liver diseases (SLDs). Expansion of immunosuppressive myeloid cells is a hallmark of inflammation and cancer,
Externí odkaz:
https://doaj.org/article/023f817342b74e968922605adf63aef4
Autor:
Aya Abou Hammoud, Julie Giraud, Xavier Gauthereau, Camille Blanchard, Sophie Daburon, Marco Zese, Silvia Molina-Castro, Pierre Dubus, Christine Varon, Helene Boeuf
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3293 (2023)
Cancer stem cells are a subpopulation of tumor cells characterized by their ability to self-renew, induce tumors upon engraftment in animals and exhibit strong resistance to chemotherapy and radiotherapy. These cells exhibit numerous characteristics
Externí odkaz:
https://doaj.org/article/e2dc8c60202e4af9b0611adab26d74a3
Autor:
Silvia Elena Molina-Castro, Camille Tiffon, Julie Giraud, Hélène Boeuf, Elodie Sifre, Alban Giese, Geneviève Belleannée, Philippe Lehours, Emilie Bessède, Francis Mégraud, Pierre Dubus, Cathy Staedel, Christine Varon
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 257-276 (2020)
Background & Aims: Gastric carcinoma is related mostly to CagA+-Helicobacter pylori infection, which disrupts the gastric mucosa turnover and elicits an epithelial-mesenchymal transition (EMT) and preneoplastic transdifferentiation. The tumor suppres
Externí odkaz:
https://doaj.org/article/5f0b0c73c00e4cd0a7d97071ba0d863b
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hepatocellular carcinoma (HCC) is the most common liver tumor and among the deadliest cancers worldwide. Advanced HCC overall survival is meager and has not improved over the last decade despite approval of several tyrosine kinase inhibitors (TKi) fo
Externí odkaz:
https://doaj.org/article/78944b22f11b4e14b0db4d7295a4281a
Autor:
Camille Tiffon, Julie Giraud, Silvia Elena Molina-Castro, Sara Peru, Lornella Seeneevassen, Elodie Sifré, Cathy Staedel, Emilie Bessède, Pierre Dubus, Francis Mégraud, Philippe Lehours, Océane C.B. Martin, Christine Varon
Publikováno v:
Cells, Vol 9, Iss 6, p 1462 (2020)
Helicobacter pylori infection, the main risk factor for gastric cancer (GC), leads to an epithelial–mesenchymal transition (EMT) of gastric epithelium contributing to gastric cancer stem cell (CSC) emergence. The Hippo pathway effectors yes-associa
Externí odkaz:
https://doaj.org/article/1561b2b429034b62a76430f8af6d91bd
Autor:
Julie Giraud, Lornella Seeneevassen, Benoit Rousseau, Damien Bouriez, Elodie Sifré, Alban Giese, Tra Ly Nguyen, Camille Tiffon, Yannick Lippi, Lamia Azzi-Martin, Julie Pannequin, Armelle Ménard, Emilie Bessède, Cathy Staedel, Francis Mégraud, Geneviève Belleannée, Philippe Lehours, Caroline Gronnier, Pierre Dubus, Christine Varon
Publikováno v:
Gastric Cancer
Gastric Cancer, In press, 26 (2), pp.234-249. ⟨10.1007/s10120-022-01357-y⟩
Gastric Cancer, In press, 26 (2), pp.234-249. ⟨10.1007/s10120-022-01357-y⟩
Background Cancer stem cells (CSCs) are at the origin of tumour initiation and progression in gastric adenocarcinoma (GC). However, markers of metastasis-initiating cells remain unidentified in GC. In this study, we characterized CD44 variants expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33518a9aea0738828443f6ece3fdbf63
https://doi.org/10.1007/s10120-022-01357-y
https://doi.org/10.1007/s10120-022-01357-y
Autor:
Christine Varon, Frédéric Mazurier, Francis Mégraud, Nathalie Senant-Dugot, Benoit Rousseau, Serge Evrard, Isabelle Soubeyran, Denis Collet, Geneviève Belleannée, Linda Wittkop, Pierre Dubus, Lucie Chambonnier, Julie Giraud, Phu Hung Nguyen
Detection of cells expressing CD44 and ALDH activity in gastric tumorspheres in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31317a861305c617310d24385619637f
https://doi.org/10.1158/1078-0432.22456746.v1
https://doi.org/10.1158/1078-0432.22456746.v1
Autor:
Christine Varon, Frédéric Mazurier, Francis Mégraud, Nathalie Senant-Dugot, Benoit Rousseau, Serge Evrard, Isabelle Soubeyran, Denis Collet, Geneviève Belleannée, Linda Wittkop, Pierre Dubus, Lucie Chambonnier, Julie Giraud, Phu Hung Nguyen
Effect of verapamil treatment in combination with dose-dependent chemotherapies on gastric cancer cell lines viability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad17c33977da7caedb63fdcdb360735
https://doi.org/10.1158/1078-0432.22456740
https://doi.org/10.1158/1078-0432.22456740
Autor:
Christine Varon, Frédéric Mazurier, Francis Mégraud, Nathalie Senant-Dugot, Benoit Rousseau, Serge Evrard, Isabelle Soubeyran, Denis Collet, Geneviève Belleannée, Linda Wittkop, Pierre Dubus, Lucie Chambonnier, Julie Giraud, Phu Hung Nguyen
Detection of ALDH+ population with SP protocol and with ALDEFLUOR protocol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a46862cfc4b8d0df133ea2c2090a0e2
https://doi.org/10.1158/1078-0432.22456743.v1
https://doi.org/10.1158/1078-0432.22456743.v1