Výsledky vyhledávání - "Julie Fields Liu"

ChemInform Abstract: Total Synthesis of (.+-.)-Cylindricines A (I) and B (II)

Autor: Clayton H. Heathcock, Julie Fields Liu

Publikováno v: ChemInform. 31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::404475ffa2dd799ac952ecd05be5e963
https://doi.org/10.1002/chin.200007184

Zobrazit plný text záznamu

Total Synthesis of (+/-)-Cylindricines A and B

Autor: Julie Fields Liu, Clayton H. Heathcock

Publikováno v: The Journal of organic chemistry. 64(22)

Cylindricine A (1) and cylindricine B (2) have been synthesized in 11 steps and 19% overall yield. The key reaction involves the addition of an organocopper species to a bicyclic vinylogous amide, which provides complete stereocontrol over the instal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff58f97c0f2fa5fc2b4254e0f87fa55
https://pubmed.ncbi.nlm.nih.gov/11674746

Zobrazit plný text záznamu

Abstract 3357: CTP-221, a deuterated S-enantiomer of lenalidomide, is greatly stabilized to epimerization and results in a more desirable pharmacokinetic profile than racemic lenalidomide

Autor: Changfu Cheng, Ara M. Aslanian, Roger Tung, Vinita Uttamsingh, Julie Fields Liu, Richard Gallegos, Lijun Wu

Publikováno v: Cancer Research. 73:3357-3357

IMiD-class compounds, including thalidomide, lenalidomide, and pomalidomide, have been developed as racemic mixtures of S- and R-enantiomers. The isolated enantiomers of thalidomide are known to have distinct biological activities. For example, the w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2b1238c8e73c5a6d32ccb164a352fa0
https://doi.org/10.1158/1538-7445.am2013-3357

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání