Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Julie Elliott"'
Autor:
Jennifer A. Fulcher, Fan Li, Nicole H. Tobin, Sara Zabih, Julie Elliott, Jesse L. Clark, Richard D'Aquila, Brian Mustanski, Michele D. Kipke, Steven Shoptaw, Pamina M. Gorbach, Grace M. Aldrovandi
Publikováno v:
EBioMedicine, Vol 84, Iss , Pp 104286- (2022)
Summary: Background: Alterations in the gut microbiome have been associated with HIV infection, but the relative impact of HIV versus other factors on the gut microbiome has been difficult to determine in cross-sectional studies. Methods: To address
Externí odkaz:
https://doaj.org/article/23bd71f4f19f40499873ba16fe16f2ef
Autor:
Ashley N. Gray, Rachel Martin-Blais, Nicole H. Tobin, Yan Wang, Sarah L. Brooker, Fan Li, Adva Gadoth, Julie Elliott, Emmanuelle Faure-Kumar, Megan Halbrook, Christian Hofmann, Saman Kashani, Clayton Kazan, Otto O. Yang, Jennifer A. Fulcher, Kathie Grovit-Ferbas, Anne W. Rimoin, Grace M. Aldrovandi
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Two mRNA vaccines (BNT162b2 and mRNA-1273) against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) are globally authorized as a two-dose regimen. Understanding the magnitude and duration of protective immune responses is vital to curbing
Externí odkaz:
https://doaj.org/article/45bfdda4834741c0968fc739206bab21
Autor:
Jeffrey Dock, Christina M Ramirez, Lance Hultin, Mary Ann Hausner, Patricia Hultin, Julie Elliott, Otto O Yang, Peter A Anton, Beth D Jamieson, Rita B Effros
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182498 (2017)
A hallmark of human immunosenescence is the accumulation of late-differentiated memory CD8+ T cells with features of replicative senescence, such as inability to proliferate, absence of CD28 expression, shortened telomeres, loss of telomerase activit
Externí odkaz:
https://doaj.org/article/6bab4bfe0b8e4d8192471bd15f0484c3
Autor:
Ian McGowan, Peter A Anton, Julie Elliott, Ross D Cranston, Kathryn Duffill, Andrew D Althouse, Kevin L Hawkins, Stephen C De Rosa
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126454 (2015)
The purpose of this study was to determine whether the development of a standardized approach to the collection of intestinal tissue from healthy volunteers, isolation of gut associated lymphoid tissue mucosal mononuclear cells (MMC), and characteriz
Externí odkaz:
https://doaj.org/article/9947ef175f3f4e20b0169d0cd625a614
Autor:
Ian Mcgowan, Ross D Cranston, Kathryn Duffill, Aaron Siegel, Jarret C Engstrom, Alexyi Nikiforov, Cindy Jacobson, Khaja K Rehman, Julie Elliott, Elena Khanukhova, Kaleab Abebe, Christine Mauck, Hans M L Spiegel, Charlene S Dezzutti, Lisa C Rohan, Mark A Marzinke, Hiwot Hiruy, Craig W Hendrix, Nicola Richardson-Harman, Peter A Anton
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125363 (2015)
The CHARM-01 study characterized the safety, acceptability, pharmacokinetics (PK), and pharmacodynamics (PD) of three tenofovir (TFV) gels for rectal application. The vaginal formulation (VF) gel was previously used in the CAPRISA 004 and VOICE vagin
Externí odkaz:
https://doaj.org/article/2b34f4f71e194ee9b4595419b03dbb92
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122723 (2015)
Mucosal tissues are critical immune effector sites containing complex populations of leukocytes in a tissue microenvironment that remains incompletely understood. We identify and quantify in human distal colorectal tissue absolute mucosal CD3+ lympho
Externí odkaz:
https://doaj.org/article/667f7e8a700641599fdadae131cd13e0
Autor:
Nicola Richardson-Harman, Craig W Hendrix, Namandjé N Bumpus, Christine Mauck, Ross D Cranston, Kuo Yang, Julie Elliott, Karen Tanner, Ian McGowan, Angela Kashuba, Peter A Anton
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111507 (2014)
This study was designed to assess the dose-response relationship between tissue, blood, vaginal and rectal compartment concentrations of tenofovir (TFV) and tenofovir diphosphate (TFVdp) and ex vivo rectal HIV suppression following oral tenofovir dis
Externí odkaz:
https://doaj.org/article/f70bae59fc544b72b18cb743db316f16
Autor:
Otto O Yang, F Javier Ibarrondo, Charles Price, Lance E Hultin, Julie Elliott, Patricia M Hultin, Roger Shih, Mary Ann Hausner, Hwee L Ng, Jennifer Hoffman, Beth D Jamieson, Peter A Anton
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88621 (2014)
Mucosal immunity is central to sexual transmission and overall pathogenesis of HIV-1 infection, but the ability of vaccines to induce immune responses in mucosal tissue compartments is poorly defined. Because macaque vaccine studies suggest that ingu
Externí odkaz:
https://doaj.org/article/aabb0ec4ee86403e84bd97d2a892933e
Autor:
Kuo-Hsiung Yang, Craig Hendrix, Namandje Bumpus, Julie Elliott, Karen Tanner, Christine Mauck, Ross Cranston, Ian McGowan, Nicola Richardson-Harman, Peter A Anton, Angela D M Kashuba
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e106196 (2014)
This Phase 1, randomized, two-site (United States), double-blind, placebo-controlled study enrolled 18 sexually abstinent men and women. All received a single 300-mg dose of oral tenofovir disoproxil fumarate (TDF) and were then randomized 2:1 to rec
Externí odkaz:
https://doaj.org/article/9f2b358de802411cacb2075532cf09b7
Autor:
Martha J Lewis, Patricia Frohnen, F Javier Ibarrondo, Diane Reed, Varun Iyer, Hwee L Ng, Julie Elliott, Otto O Yang, Peter Anton
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75620 (2013)
The gut is the largest lymphoid organ in the body and a site of active HIV-1 replication and immune surveillance. The gut is a reservoir of persistent infection in some individuals with fully suppressed plasma viremia on combination antiretroviral th
Externí odkaz:
https://doaj.org/article/ec8e584b732741e483100f2ef4d7caf2