Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Julie Eiseman"'
Autor:
Susan E. Bates, Jan H. Beumer, Edward Chu, Julie Eiseman, Chandra P. Belani, Yixing Jiang, David R. Kohler, Richard Piekarz, John J. Wright, William M. Bonner, Asako J. Nakamura, Christophe E. Redon, Christine Bryla, Robert A. Parise, Sanjeeve Balasubramaniam, Leonard J. Appleman
Supplementary Tables 1-3. Supplemental Table 1. Plasma pharmacokinetics of DMS612 metabolites. Supplemental Table 2. Pharmacodynamic assessment of !-H2AX detection in PBMCs. Mean values for !-H2AX foci per cell with DMS612 doses of 1.5, 3, 5, 7, 9 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acbe4e4740497e7dc390afc20e3a505
https://doi.org/10.1158/1078-0432.22459742.v1
https://doi.org/10.1158/1078-0432.22459742.v1
Autor:
Yves Pommier, James H. Doroshow, Jan H. Beumer, Julie Eiseman, Miguel Muzzio, Julianne L. Holleran, Joseph Tomaszewski, Heather Wilson-Robles, Nicole Northup, Kelvin Kow, Timothy Fan, Michael Kent, E.J. Ehrhart, Lisa Barber, Jeffrey N. Bryan, Michael Childress, David Vail, Erika Krick, William Kisseberth, Cheryl London, Kristen Weishaar, Sue Lana, Melissa Paoloni, Chand Khanna, Ralph E. Parchment, Robert J. Kinders, Jiuping Ji, Joseph M. Covey, Amy LeBlanc, Christina Mazcko, Jenna H. Burton
All supplementary files together
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bc47299d9db5f59422b41191ade8c3
https://doi.org/10.1158/1078-0432.22469313
https://doi.org/10.1158/1078-0432.22469313
Autor:
Susan E. Bates, Jan H. Beumer, Edward Chu, Julie Eiseman, Chandra P. Belani, Yixing Jiang, David R. Kohler, Richard Piekarz, John J. Wright, William M. Bonner, Asako J. Nakamura, Christophe E. Redon, Christine Bryla, Robert A. Parise, Sanjeeve Balasubramaniam, Leonard J. Appleman
Supplementary Tables 1-3. Supplemental Table 1. Plasma pharmacokinetics of DMS612 metabolites. Supplemental Table 2. Pharmacodynamic assessment of !-H2AX detection in PBMCs. Mean values for !-H2AX foci per cell with DMS612 doses of 1.5, 3, 5, 7, 9 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba32d1447dceac41dec2087dbd87fa2
https://doi.org/10.1158/1078-0432.22459736
https://doi.org/10.1158/1078-0432.22459736
Autor:
Susan E. Bates, Jan H. Beumer, Edward Chu, Julie Eiseman, Chandra P. Belani, Yixing Jiang, David R. Kohler, Richard Piekarz, John J. Wright, William M. Bonner, Asako J. Nakamura, Christophe E. Redon, Christine Bryla, Robert A. Parise, Sanjeeve Balasubramaniam, Leonard J. Appleman
Purpose: DMS612 is a dimethane sulfonate analog with bifunctional alkylating activity and preferential cytotoxicity to human renal cell carcinoma (RCC) in the NCI-60 cell panel. This first-in-human phase I study aimed to determine dose-limiting toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c386b22930b1b7e47c7585e83585d4
https://doi.org/10.1158/1078-0432.c.6524294.v1
https://doi.org/10.1158/1078-0432.c.6524294.v1
Autor:
Yves Pommier, James H. Doroshow, Jan H. Beumer, Julie Eiseman, Miguel Muzzio, Julianne L. Holleran, Joseph Tomaszewski, Heather Wilson-Robles, Nicole Northup, Kelvin Kow, Timothy Fan, Michael Kent, E.J. Ehrhart, Lisa Barber, Jeffrey N. Bryan, Michael Childress, David Vail, Erika Krick, William Kisseberth, Cheryl London, Kristen Weishaar, Sue Lana, Melissa Paoloni, Chand Khanna, Ralph E. Parchment, Robert J. Kinders, Jiuping Ji, Joseph M. Covey, Amy LeBlanc, Christina Mazcko, Jenna H. Burton
Purpose:Only one chemical class of topoisomerase I (TOP1) inhibitors is FDA approved, the camptothecins with irinotecan and topotecan widely used. Because of their limitations (chemical instability, drug efflux-mediated resistance, and diarrhea), nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36108e2ffff164835c28b3a1445044dc
https://doi.org/10.1158/1078-0432.c.6527208
https://doi.org/10.1158/1078-0432.c.6527208
Autor:
Kristen M. Weishaar, Melissa Paoloni, Heather Wilson-Robles, Michael O. Childress, Christina Mazcko, Jenna H Burton, Yves Pommier, Michael S. Kent, Nicole Northup, Erika Krick, Joseph E. Tomaszewski, James H. Doroshow, Jiuping Ji, Timothy M. Fan, Cheryl A. London, Lisa G. Barber, William C. Kisseberth, David M. Vail, Robert J. Kinders, Jan H Beumer, Ralph E. Parchment, Chand Khanna, Miguel Muzzio, Amy K. LeBlanc, EJ Ehrhart, Julie Eiseman, Susan E. Lana, Joseph M. Covey, Julianne L. Holleran, Jeffrey N. Bryan, Kelvin Y Kow
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 24, iss 23
Purpose: Only one chemical class of topoisomerase I (TOP1) inhibitors is FDA approved, the camptothecins with irinotecan and topotecan widely used. Because of their limitations (chemical instability, drug efflux-mediated resistance, and diarrhea), no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195f890eef28379dc62ccbdeaccf96cb
https://escholarship.org/uc/item/2zt0643k
https://escholarship.org/uc/item/2zt0643k
Publikováno v:
Journal of Pharmacokinetics & Pharmacodynamics; Feb2005, Vol. 32 Issue 1, p65-83, 19p
Publikováno v:
Breast Cancer Research & Treatment; Jun2003, Vol. 79 Issue 3, p301-312, 12p
Publikováno v:
Biochemical Pharmacology. 24:779-783
Cutaneous application in rats of two widely used microscope immersion oils known to contain the environmental pollutant chemicals, polychlorinated biphenyls, was evaluated. After skin application of 1 or 10 μl of these oils, significant increases in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915d9577185671a5bbfe5fbe5fee7c44
https://doi.org/10.1016/0006-2952(75)90120-3
https://doi.org/10.1016/0006-2952(75)90120-3
Autor:
Wilk, Anna1,2, Hayat, Faisal1,2, Cunningham, Richard1,2, Li, Jianfeng1,2, Garavaglia, Silvia3, Zamani, Leila1, Ferraris, Davide M.3, Sykora, Peter1,4, Andrews, Joel1, Clark, Jennifer1,2, Davis, Amanda1, Chaloin, Laurent5, Rizzi, Menico3, Migaud, Marie1,2, Sobol, Robert W.1,2 rwsobol@health.southalabama.edu
Publikováno v:
Scientific Reports. 1/20/2020, Vol. 10 Issue 1, p1-21. 21p.