Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Julie E. Stein"'
Autor:
Nicolas A. Giraldo, Peter Nguyen, Elizabeth L. Engle, Genevieve J. Kaunitz, Tricia R. Cottrell, Sneha Berry, Benjamin Green, Abha Soni, Jonathan D. Cuda, Julie E. Stein, Joel C. Sunshine, Farah Succaria, Haiying Xu, Aleksandra Ogurtsova, Ludmila Danilova, Candice D. Church, Natalie J. Miller, Steve Fling, Lisa Lundgren, Nirasha Ramchurren, Jennifer H. Yearley, Evan J. Lipson, Mac Cheever, Robert A. Anders, Paul T. Nghiem, Suzanne L. Topalian, Janis M. Taube
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background We recently reported a 56% objective response rate in patients with advanced Merkel cell carcinoma (MCC) receiving pembrolizumab. However, a biomarker predicting clinical response was not identified. Methods Pretreatment FFPE tumo
Externí odkaz:
https://doaj.org/article/76e43af2693646548cca3682365754c1
Autor:
Bin Li, Jun Li, Tian Chen, Uwe M Martens, Lazar Vujanovic, Rom Leidner, Robert L Ferris, William Sharfman, Chrisann Kyi, Suzanne L Topalian, Janis M Taube, Christine H Chung, William C Spanos, Anthony Gonçalves, Lot A Devriese, Helene Gauthier, Simon I Chiosea, Julie E Stein, Adam Barrows
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Head and neck squamous cell carcinomas (HNSCCs) are common malignancies caused by carcinogens, including tobacco and alcohol, or infection with human papillomavirus (HPV). Immune checkpoint inhibitors targeting the programmed cell death 1
Externí odkaz:
https://doaj.org/article/5b3e3b1bc7294331bf25fd5f151678dd
Autor:
Travis J. Hollmann, Ingo K. Mellinghoff, Nicholas D. Socci, Andrea Schietinger, Margaret K. Callahan, Fiona Ginty, Elizabeth McDonough, Alex D. Corwin, Stephanie L. Goff, Billel Gasmi, John M. Kirkwood, Jennifer A. Wargo, Raymond Traweek, Michael G. White, Janis M. Taube, Julie E. Stein, Kara M. Schenk, Evan J. Lipson, Thomas Brenn, Claire F. Temple-Oberle, David S. Klimstra, Saad Nadeem, Carl Campos, Subhiksha Nandakumar, Mianlei Zhang, Yanyun Li, Daniel A. Navarrete, Mono Pirun, Zheng Zeng, Charlotte E. Ariyan, Caitlin J. Jones, Maryam Pourmaleki
Cancer immunotherapy can result in lasting tumor regression, but predictive biomarkers of treatment response remain ill-defined. Here, we performed single-cell proteomics, transcriptomics, and genomics on matched untreated and IL2 injected metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216f1dd5447158b61cd71a0e6db3b398
https://doi.org/10.1158/2326-6066.c.6550763
https://doi.org/10.1158/2326-6066.c.6550763
Autor:
Travis J. Hollmann, Ingo K. Mellinghoff, Nicholas D. Socci, Andrea Schietinger, Margaret K. Callahan, Fiona Ginty, Elizabeth McDonough, Alex D. Corwin, Stephanie L. Goff, Billel Gasmi, John M. Kirkwood, Jennifer A. Wargo, Raymond Traweek, Michael G. White, Janis M. Taube, Julie E. Stein, Kara M. Schenk, Evan J. Lipson, Thomas Brenn, Claire F. Temple-Oberle, David S. Klimstra, Saad Nadeem, Carl Campos, Subhiksha Nandakumar, Mianlei Zhang, Yanyun Li, Daniel A. Navarrete, Mono Pirun, Zheng Zeng, Charlotte E. Ariyan, Caitlin J. Jones, Maryam Pourmaleki
Supplementary Data from Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ff20e918c38d910b51acc978910ea8
https://doi.org/10.1158/2326-6066.22544855.v1
https://doi.org/10.1158/2326-6066.22544855.v1
Autor:
Janis M. Taube, Alexander S. Baras, Ludmila Danilova, Evan J. Lipson, Robert A. Anders, Raphael Gottardo, Haiying Xu, Aleksandra Ogurtsova, Farah Succaria, Julie E. Stein, Abha Soni, Peter Nguyen, Benjamin Green, Elizabeth L. Engle, Kara M. Schenk, Deniz Ates, Etienne Becht, Sneha Berry, Nicolas A. Giraldo
Supplementary Table S1. Clinicopathologic characteristics of the cohort separated by death at the 5-year time point. Supplementary Table S2. Primary and secondary antibody information and TSA dye pairings for multiplex IF panel. Supplementary Table S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b89535a3a53003ce18b4d960476f4dd
https://doi.org/10.1158/2326-6066.22544504.v1
https://doi.org/10.1158/2326-6066.22544504.v1
Autor:
Janis M. Taube, Alexander S. Baras, Ludmila Danilova, Evan J. Lipson, Robert A. Anders, Raphael Gottardo, Haiying Xu, Aleksandra Ogurtsova, Farah Succaria, Julie E. Stein, Abha Soni, Peter Nguyen, Benjamin Green, Elizabeth L. Engle, Kara M. Schenk, Deniz Ates, Etienne Becht, Sneha Berry, Nicolas A. Giraldo
Multiplex immunofluorescence (mIF) can detail spatial relationships and complex cell phenotypes in the tumor microenvironment (TME). However, the analysis and visualization of mIF data can be complex and time-consuming. Here, we used tumor specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0d03623d3094440ff71bafc7f4972d
https://doi.org/10.1158/2326-6066.c.6550664
https://doi.org/10.1158/2326-6066.c.6550664
Autor:
Janis M. Taube, Suzanne L. Topalian, Drew M. Pardoll, Elizabeth M. Jaffee, Hao Wang, Josephine Feliciano, Mark Yarchoan, Mohamad E. Allaf, Elizabeth D. Thompson, Ashley Cimino-Mathews, Robert A. Anders, Patrick M. Forde, Tricia R. Cottrell, Evan J. Lipson, Julie E. Stein
Supplemental Appendix (Figures S1 and S2, Table S1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ed1e4bdcd90cc74ca63e179954003f
https://doi.org/10.1158/1078-0432.22479647
https://doi.org/10.1158/1078-0432.22479647
Autor:
Janis M. Taube, Suzanne L. Topalian, Drew M. Pardoll, Elizabeth M. Jaffee, Hao Wang, Josephine Feliciano, Mark Yarchoan, Mohamad E. Allaf, Elizabeth D. Thompson, Ashley Cimino-Mathews, Robert A. Anders, Patrick M. Forde, Tricia R. Cottrell, Evan J. Lipson, Julie E. Stein
Purpose:Pathologic response assessment of tumor specimens from patients receiving systemic treatment provides an early indication of therapeutic efficacy and predicts long-term survival. Grading systems for pathologic response were first developed fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306dceea7e36d45e003608408c669dff
https://doi.org/10.1158/1078-0432.c.6530270
https://doi.org/10.1158/1078-0432.c.6530270
Autor:
Maryam Pourmaleki, Caitlin J. Jones, Charlotte E. Ariyan, Zheng Zeng, Mono Pirun, Daniel A. Navarrete, Yanyun Li, Mianlei Zhang, Subhiksha Nandakumar, Carl Campos, Saad Nadeem, David S. Klimstra, Claire F. Temple-Oberle, Thomas Brenn, Evan J. Lipson, Kara M. Schenk, Julie E. Stein, Janis M. Taube, Michael G. White, Raymond Traweek, Jennifer A. Wargo, John M. Kirkwood, Billel Gasmi, Stephanie L. Goff, Alex D. Corwin, Elizabeth McDonough, Fiona Ginty, Margaret K. Callahan, Andrea Schietinger, Nicholas D. Socci, Ingo K. Mellinghoff, Travis J. Hollmann
Publikováno v:
Cancer Immunol Res
Cancer immunotherapy can result in lasting tumor regression, but predictive biomarkers of treatment response remain ill-defined. Here, we performed single-cell proteomics, transcriptomics, and genomics on matched untreated and IL2 injected metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d97b6ae75f26d31249a3f4a9bcd3e42
https://doi.org/10.1158/2326-6066.cir-21-1083
https://doi.org/10.1158/2326-6066.cir-21-1083
Autor:
Janis M. Taube, Hans J. Hammers, Charles G. Drake, Julie E. Stein, Phillip M. Pierorazio, Alice Pons, Noah M. Hahn, Daniela C. Salles, Hiten D. Patel, Tamara L. Lotan, Michael A. Gorin, Steven P. Rowe, Mohamad E. Allaf, Bruce J. Trock, Thomas R. Nirschl
Publikováno v:
European Urology Oncology. 5:113-117
Neoadjuvant immune checkpoint blockade represents a novel approach for potentially decreasing the risk of recurrence in patients with nonmetastatic renal cell carcinoma (RCC). In this early phase clincal tiral, we evaluated the safety and tolerabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e94f634f464222445746b21feedae0
https://doi.org/10.1016/j.euo.2021.04.002
https://doi.org/10.1016/j.euo.2021.04.002