Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Julie E. Baggs"'
Autor:
Lauren J. Manderfield, Kurt A. Engleka, Haig Aghajanian, Mudit Gupta, Steven Yang, Li Li, Julie E. Baggs, John B. Hogenesch, Eric N. Olson, Jonathan A. Epstein
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1885-1895 (2014)
Summary: Loss of Pax3, a developmentally regulated transcription factor expressed in premigratory neural crest, results in severe developmental defects and embryonic lethality. Although Pax3 mutations produce profound phenotypes, the intrinsic transc
Externí odkaz:
https://doaj.org/article/7a3af8f78e1d43abafc1641aa5ecd11c
Autor:
Lauren J. Manderfield, Kurt A. Engleka, Haig Aghajanian, Mudit Gupta, Steven Yang, Li Li, Julie E. Baggs, John B. Hogenesch, Eric N. Olson, Jonathan A. Epstein
Publikováno v:
Cell Reports, Vol 10, Iss 5, p 841 (2015)
Externí odkaz:
https://doaj.org/article/d84048657f554299bba4e5ad25df1227
Autor:
Tsedey Mekbib, Ting-Chung Suen, Aisha Rollins-Hairston, Kiandra Smith, Ariel Armstrong, Cloe Gray, Sharon Owino, Kenkichi Baba, Julie E Baggs, J Christopher Ehlen, Gianluca Tosini, Jason P DeBruyne
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010305 (2022)
Circadian clocks enable organisms to predict and align their behaviors and physiologies to constant daily day-night environmental cycle. Because the ubiquitin ligase Siah2 has been identified as a potential regulator of circadian clock function in cu
Externí odkaz:
https://doaj.org/article/be0a2af3db4e4fe7b9abc59d1a0f7b5d
Autor:
Daniel P Beiting, Shinya Hidano, Julie E Baggs, Jeanne M Geskes, Qun Fang, E John Wherry, Christopher A Hunter, David S Roos, Sara Cherry
Publikováno v:
PLoS Biology, Vol 13, Iss 7, p e1002200 (2015)
The protozoan parasite, Toxoplasma, like many intracellular pathogens, suppresses interferon gamma (IFN-γ)-induced signal transducer and activator of transcription 1 (STAT1) activity. We exploited this well-defined host-pathogen interaction as the b
Externí odkaz:
https://doaj.org/article/58f2cfedb6824570a21d6c85c0d5c279
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55782 (2013)
Previous studies have demonstrated that certain Wnt ligands can promote high levels of cooperative signaling in a cell type specific manner. To explore the underlying mechanism of this cooperative Wnt signaling, we performed a high-throughput screen
Externí odkaz:
https://doaj.org/article/ce3c453a6a6a4a6096bf4a6905ef01c6
Autor:
Jason P. DeBruyne, Ting-Chung Suen, Julie E. Baggs, J. Christopher Ehlen, Gianluca Tosini, Ariel Armstrong, Aisha Rollins-Hairston, Kenkichi Baba, Cloe L Gray, Sharon Owino, Kiandra Smith, Tsedey Mekbib
Circadian clocks enable organisms to predict and align their behaviors and physiologies to constant daily day-night environmental cycle. Because the ubiquitin ligase Siah2 has been identified as a potential regulator of circadian clock function in cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad88c89c0bec86212c15516a545cd777
https://doi.org/10.1101/2020.10.05.326652
https://doi.org/10.1101/2020.10.05.326652
Autor:
Jingshing Wu, Julie E. Baggs, David Merrick, Nikolay Gresko, Zhaoxia Sun, Michael J. Caplan, John B. Hogenesch, Kavita Mistry
Publikováno v:
Human molecular genetics. 28(1)
Polycystin-1 (PC1), encoded by the PKD1 gene that is mutated in the autosomal dominant polycystic kidney disease, regulates a number of processes including bone development. Activity of the transcription factor RunX2, which controls osteoblast differ
Autor:
Christine Winterstein, Adrian J. Giovannone, Matthew A. Lalli, Julie E. Baggs, Mimi Xu, Elena Reales, Thomas Weimbs, Pallavi Bhattaram, Seng Hui Low, John B. Hogenesch
Publikováno v:
The Journal of biological chemistry, vol 293, iss 15
Syntaxins are a conserved family of SNARE proteins and contain C-terminal transmembrane anchors required for their membrane fusion activity. Here we show that Stx3 (syntaxin 3) unexpectedly also functions as a nuclear regulator of gene expression. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f489887f123ba93b4fde52e0b6ba41
https://europepmc.org/articles/PMC5900775/
https://europepmc.org/articles/PMC5900775/
Publikováno v:
Proceedings of the National Academy of Sciences. 112:12420-12425
Regulated degradation of proteins by the proteasome is often critical to their function in dynamic cellular pathways. The molecular clock underlying mammalian circadian rhythms relies on the rhythmic expression and degradation of its core components.
Autor:
Mudit Gupta, John B. Hogenesch, Julie E. Baggs, Steven Yang, Jonathan A. Epstein, Kurt A. Engleka, Lauren J. Manderfield, Eric N. Olson, Haig Aghajanian, Li Li
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1885-1895 (2014)
Cell Reports, Vol 10, Iss 5, p 841 (2015)
Cell Reports, Vol 10, Iss 5, p 841 (2015)
Summary: Loss of Pax3, a developmentally regulated transcription factor expressed in premigratory neural crest, results in severe developmental defects and embryonic lethality. Although Pax3 mutations produce profound phenotypes, the intrinsic transc