Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Julie E Baggs"'
Autor:
Tsedey Mekbib, Ting-Chung Suen, Aisha Rollins-Hairston, Kiandra Smith, Ariel Armstrong, Cloe Gray, Sharon Owino, Kenkichi Baba, Julie E Baggs, J Christopher Ehlen, Gianluca Tosini, Jason P DeBruyne
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010305 (2022)
Circadian clocks enable organisms to predict and align their behaviors and physiologies to constant daily day-night environmental cycle. Because the ubiquitin ligase Siah2 has been identified as a potential regulator of circadian clock function in cu
Externí odkaz:
https://doaj.org/article/be0a2af3db4e4fe7b9abc59d1a0f7b5d
Autor:
Daniel P Beiting, Shinya Hidano, Julie E Baggs, Jeanne M Geskes, Qun Fang, E John Wherry, Christopher A Hunter, David S Roos, Sara Cherry
Publikováno v:
PLoS Biology, Vol 13, Iss 7, p e1002200 (2015)
The protozoan parasite, Toxoplasma, like many intracellular pathogens, suppresses interferon gamma (IFN-γ)-induced signal transducer and activator of transcription 1 (STAT1) activity. We exploited this well-defined host-pathogen interaction as the b
Externí odkaz:
https://doaj.org/article/58f2cfedb6824570a21d6c85c0d5c279
Autor:
Ron C Anafi, Yool Lee, Trey K Sato, Anand Venkataraman, Chidambaram Ramanathan, Ibrahim H Kavakli, Michael E Hughes, Julie E Baggs, Jacqueline Growe, Andrew C Liu, Junhyong Kim, John B Hogenesch
Publikováno v:
PLoS Biology, Vol 12, Iss 4, p e1001840 (2014)
Over the last decades, researchers have characterized a set of "clock genes" that drive daily rhythms in physiology and behavior. This arduous work has yielded results with far-reaching consequences in metabolic, psychiatric, and neoplastic disorders
Externí odkaz:
https://doaj.org/article/9524308b57ad4b38a1489326a7186b21
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55782 (2013)
Previous studies have demonstrated that certain Wnt ligands can promote high levels of cooperative signaling in a cell type specific manner. To explore the underlying mechanism of this cooperative Wnt signaling, we performed a high-throughput screen
Externí odkaz:
https://doaj.org/article/ce3c453a6a6a4a6096bf4a6905ef01c6
Autor:
Michael E Hughes, Luciano DiTacchio, Kevin R Hayes, Christopher Vollmers, S Pulivarthy, Julie E Baggs, Satchidananda Panda, John B Hogenesch
Publikováno v:
PLoS Genetics, Vol 5, Iss 4, p e1000442 (2009)
The circadian clock is a molecular and cellular oscillator found in most mammalian tissues that regulates rhythmic physiology and behavior. Numerous investigations have addressed the contribution of circadian rhythmicity to cellular, organ, and organ
Externí odkaz:
https://doaj.org/article/52eb31838bd24f8f8fa141e970c61dcc
Autor:
Julie E Baggs, Tom S Price, Luciano DiTacchio, Satchidananda Panda, Garret A Fitzgerald, John B Hogenesch
Publikováno v:
PLoS Biology, Vol 7, Iss 3, p e52 (2009)
The mammalian circadian clock is a cell-autonomous system that drives oscillations in behavior and physiology in anticipation of daily environmental change. To assess the robustness of a human molecular clock, we systematically depleted known clock c
Externí odkaz:
https://doaj.org/article/8ea60c859af24d80ba4012c42648648a
Autor:
Jason P. DeBruyne, Ting-Chung Suen, Julie E. Baggs, J. Christopher Ehlen, Gianluca Tosini, Ariel Armstrong, Aisha Rollins-Hairston, Kenkichi Baba, Cloe L Gray, Sharon Owino, Kiandra Smith, Tsedey Mekbib
Circadian clocks enable organisms to predict and align their behaviors and physiologies to constant daily day-night environmental cycle. Because the ubiquitin ligase Siah2 has been identified as a potential regulator of circadian clock function in cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad88c89c0bec86212c15516a545cd777
https://doi.org/10.1101/2020.10.05.326652
https://doi.org/10.1101/2020.10.05.326652
Autor:
Jingshing Wu, Julie E. Baggs, David Merrick, Nikolay Gresko, Zhaoxia Sun, Michael J. Caplan, John B. Hogenesch, Kavita Mistry
Publikováno v:
Human molecular genetics. 28(1)
Polycystin-1 (PC1), encoded by the PKD1 gene that is mutated in the autosomal dominant polycystic kidney disease, regulates a number of processes including bone development. Activity of the transcription factor RunX2, which controls osteoblast differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a570b3380565c06184d1dc6b214200
https://pubmed.ncbi.nlm.nih.gov/30215740
https://pubmed.ncbi.nlm.nih.gov/30215740
Autor:
Christine Winterstein, Adrian J. Giovannone, Matthew A. Lalli, Julie E. Baggs, Mimi Xu, Elena Reales, Thomas Weimbs, Pallavi Bhattaram, Seng Hui Low, John B. Hogenesch
Publikováno v:
The Journal of biological chemistry, vol 293, iss 15
Syntaxins are a conserved family of SNARE proteins and contain C-terminal transmembrane anchors required for their membrane fusion activity. Here we show that Stx3 (syntaxin 3) unexpectedly also functions as a nuclear regulator of gene expression. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f489887f123ba93b4fde52e0b6ba41
https://europepmc.org/articles/PMC5900775/
https://europepmc.org/articles/PMC5900775/
Publikováno v:
Proceedings of the National Academy of Sciences. 112:12420-12425
Regulated degradation of proteins by the proteasome is often critical to their function in dynamic cellular pathways. The molecular clock underlying mammalian circadian rhythms relies on the rhythmic expression and degradation of its core components.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507f0b5fa66e84f356aa4951a082dea1
https://doi.org/10.1073/pnas.1501204112
https://doi.org/10.1073/pnas.1501204112