Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Julie Dubois-Chevalier"'
Autor:
Ninon Very, Clémence Boulet, Céline Gheeraert, Alexandre Berthier, Manuel Johanns, Mohamed Bou Saleh, Loïc Guille, Fabrice Bray, Jean-Marc Strub, Marie Bobowski-Gerard, Francesco P. Zummo, Emmanuelle Vallez, Olivier Molendi-Coste, Eloise Woitrain, Sarah Cianférani, David Montaigne, Line Carolle Ntandja-Wandji, Laurent Dubuquoy, Julie Dubois-Chevalier, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-22 (2024)
Abstract Tissue injury causes activation of mesenchymal lineage cells into wound-repairing myofibroblasts (MFs), whose uncontrolled activity ultimately leads to fibrosis. Although this process is triggered by deep metabolic and transcriptional reprog
Externí odkaz:
https://doaj.org/article/7c469a228cd14e0cb8f4aa98dabc701e
Autor:
Marie Bobowski-Gerard, Clémence Boulet, Francesco P. Zummo, Julie Dubois-Chevalier, Céline Gheeraert, Mohamed Bou Saleh, Jean-Marc Strub, Amaury Farce, Maheul Ploton, Loïc Guille, Jimmy Vandel, Antonino Bongiovanni, Ninon Very, Eloïse Woitrain, Audrey Deprince, Fanny Lalloyer, Eric Bauge, Lise Ferri, Line-Carolle Ntandja-Wandji, Alexia K. Cotte, Corinne Grangette, Emmanuelle Vallez, Sarah Cianférani, Violeta Raverdy, Robert Caiazzo, Viviane Gnemmi, Emmanuelle Leteurtre, Benoit Pourcet, Réjane Paumelle, Kim Ravnskjaer, Guillaume Lassailly, Joel T. Haas, Philippe Mathurin, François Pattou, Laurent Dubuquoy, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Myofibroblasts contribute to the development of liver fibrosis. Here, the authors report that the transcription factor Basonuclin 2 (BNC2) integrates fibrogenic signals and drives myofibroblastic transcriptional activation in liver fibrosis.
Externí odkaz:
https://doaj.org/article/c0d2d56ec91641b79809fad780054395
Autor:
Vanessa Dubois, Céline Gheeraert, Wouter Vankrunkelsven, Julie Dubois‐Chevalier, Hélène Dehondt, Marie Bobowski‐Gerard, Manjula Vinod, Francesco Paolo Zummo, Fabian Güiza, Maheul Ploton, Emilie Dorchies, Laurent Pineau, Alexis Boulinguiez, Emmanuelle Vallez, Eloise Woitrain, Eric Baugé, Fanny Lalloyer, Christian Duhem, Nabil Rabhi, Ronald E van Kesteren, Cheng‐Ming Chiang, Steve Lancel, Hélène Duez, Jean‐Sébastien Annicotte, Réjane Paumelle, Ilse Vanhorebeek, Greet Van den Berghe, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 5, Pp n/a-n/a (2020)
Abstract Liver injury triggers adaptive remodeling of the hepatic transcriptome for repair/regeneration. We demonstrate that this involves particularly profound transcriptomic alterations where acute induction of genes involved in handling of endopla
Externí odkaz:
https://doaj.org/article/25e5ed41e1224b8fae474a62d14c30b5
Autor:
Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1410-1418.e6 (2019)
Summary: Browning induction or transplantation of brown adipose tissue (BAT) or brown/beige adipocytes derived from progenitor or induced pluripotent stem cells (iPSCs) can represent a powerful strategy to treat metabolic diseases. However, our poor
Externí odkaz:
https://doaj.org/article/00e94624b982459bb752e5e8a93046f6
Publikováno v:
Epigenomics. 12:715-723
Super-enhancers (SE) have become a popular concept and are widely used as a feature defining key identity genes. Here, we provide perspectives on the use of SE to define and identify cell/tissue-identity genes. By mining SE and their associated genes
Autor:
Julie Dubois-Chevalier, Guillaume Lassailly, François Maggiotto, Line Carolle Ntandja-Wandji, Massih Ningarhari, Philippe Mathurin, Sébastien Dharancy, Pau Sancho-Bru, Laurent Dubuquoy, Emmanuel Boleslawski, Anne Corlu, Josepmaria Argemi, Florent Artru, Alexandre Louvet, Jérôme Eeckhoute, Emilie Anglo, Mohamed Bou Saleh, Stéphanie Truant, Viviane Gnemmi, Ramon Bataller
Publikováno v:
Journal of Hepatology
Journal of Hepatology, Elsevier, 2021, 75 (4), pp.912-923. ⟨10.1016/j.jhep.2021.05.041⟩
Journal of Hepatology, 2021, 75 (4), pp.912-923. ⟨10.1016/j.jhep.2021.05.041⟩
Journal of Hepatology, Elsevier, 2021, ⟨10.1016/j.jhep.2021.05.041⟩
Journal of Hepatology, Elsevier, 2021, 75 (4), pp.912-923. ⟨10.1016/j.jhep.2021.05.041⟩
Journal of Hepatology, 2021, 75 (4), pp.912-923. ⟨10.1016/j.jhep.2021.05.041⟩
Journal of Hepatology, Elsevier, 2021, ⟨10.1016/j.jhep.2021.05.041⟩
International audience; Background & AimsAlcoholic hepatitis (AH) is a life-threatening disease with limited therapeutic options, because understanding of the molecular drivers leading to death are not well understood. This study evaluates the Hippo/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945c58f194cd5c68e91fbe18c31cffe8
https://hal.univ-lille.fr/hal-03279721v2/document
https://hal.univ-lille.fr/hal-03279721v2/document
Autor:
Agnès Hovasse, Manjula Vinod, Jérôme Eeckhoute, Jeremy Alexandre, Alexandre Berthier, Julie Dubois-Chevalier, Fabrice Bray, Maheul Ploton, Xavier Marechal, Bart Staels, Christine Schaeffer-Reiss, Agata Steenackers, Hélène Duez, Philippe Lefebvre, Geoffrey Porez, Sarah Cianférani, Christian Rolando, Nao Yamakawa, Céline Gheeraert, Tony Lefebvre
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (47), pp.11033-11042. ⟨10.1073/pnas.1805397115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, Epub ahead of print. ⟨10.1073/pnas.1805397115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (47), pp.11033-11042. ⟨10.1073/pnas.1805397115⟩
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (47), pp.11033-11042. ⟨10.1073/pnas.1805397115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, Epub ahead of print. ⟨10.1073/pnas.1805397115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (47), pp.11033-11042. ⟨10.1073/pnas.1805397115⟩
Significance Using an interactomic approach, we have identified the nuclear receptor REV-ERBα as a O-GlcNAc transferase (OGT) protein partner. REV-ERBα protects cytoplasmic OGT from proteasomal degradation and facilitates cytosolic and nuclear prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fffa5683cae464f4eb9d55a699cd33
https://www.hal.inserm.fr/inserm-01924835/document
https://www.hal.inserm.fr/inserm-01924835/document
Publikováno v:
Journal of Hepatology
Autor:
François F, Firmin, Frederik, Oger, Céline, Gheeraert, Julie, Dubois-Chevalier, Anne-Sophie, Vercoutter-Edouart, Fawaz, Alzaid, Claire, Mazuy, Hélène, Dehondt, Jeremy, Alexandre, Bruno, Derudas, Quentin, Dhalluin, Maheul, Ploton, Alexandre, Berthier, Eloise, Woitrain, Tony, Lefebvre, Nicolas, Venteclef, François, Pattou, Bart, Staels, Jérôme, Eeckhoute, Philippe, Lefebvre
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.14087. ⟨10.1038/s41598-017-14570-y⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports, 2017, 7 (1), pp.14087. ⟨10.1038/s41598-017-14570-y⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.14087. ⟨10.1038/s41598-017-14570-y⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports, 2017, 7 (1), pp.14087. ⟨10.1038/s41598-017-14570-y⟩
International audience; Adipocyte differentiation and function relies on a network of transcription factors, which is disrupted in obesity-associated low grade, chronic inflammation leading to adipose tissue dysfunction. In this context, there is a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4ff2a3c1cfd4ab1ca0b30cc307ffff91
https://www.hal.inserm.fr/inserm-02159068
https://www.hal.inserm.fr/inserm-02159068
Autor:
Philippe Lefebvre, Mathieu Lupien, Jérôme Eeckhoute, Parisa Mazrooei, Bart Staels, Julie Dubois-Chevalier
Publikováno v:
Transcription
Transcription, 2018, 9 (4), pp.233-239. ⟨10.1080/21541264.2017.1394424⟩
Transcription, Taylor & Francis, 2018, 9 (4), pp.233-239. ⟨10.1080/21541264.2017.1394424⟩
PubMed Central
Transcription, 2018, 9 (4), pp.233-239. ⟨10.1080/21541264.2017.1394424⟩
Transcription, Taylor & Francis, 2018, 9 (4), pp.233-239. ⟨10.1080/21541264.2017.1394424⟩
PubMed Central
International audience; Gene transcriptional regulation relies on cis-regulatory DNA modules (CRMs), which serve as nexus sites for integration of multiple transcription factor (TF) activities. Here, we provide evidence and discuss recent literature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42dc9c2373cc18fd69eedf09fa8ada8d
https://europepmc.org/articles/PMC6104691/
https://europepmc.org/articles/PMC6104691/