Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Julie Dosescu"'
Autor:
Dora Cavallo-Medved, Julie Dosescu, Bruce E. Linebaugh, Mansoureh Sameni, Debbie Rudy, Bonnie F. Sloane
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 6, Pp 507-519 (2003)
Cathepsin B protein and activity are known to localize to the basal plasma membrane of colon carcinoma cells following the appearance of K-ras mutations. Using immunofluorescence and subcellular fractionation techniques and two human colon carcinoma
Externí odkaz:
https://doaj.org/article/7b01dd8d5fc148b791ff940f86a0b189
Publikováno v:
Molecular Imaging, Vol 7 (2008)
The ability of tumor cells to adhere to, migrate on, and remodel extracellular matrices is mediated by cell surface receptors such as β 1 -integrins. Here we conducted functional live-cell imaging in real time to investigate the effects of modulatin
Externí odkaz:
https://doaj.org/article/e715083459d147c0a5dd63e1c675d3de
Publikováno v:
Molecular Imaging, Vol 2 (2003)
The underlying basement membrane is degraded during progression of breast and colon carcinoma. Thus, we imaged degradation of a quenched fluorescent derivative of basement membrane type IV collagen (DQ-collagen IV) by living human breast and colon tu
Externí odkaz:
https://doaj.org/article/0fa43bc4d3e644f08b4bc96ec73fb877
Autor:
Robert J. Gillies, Robert A. Gatenby, Natarajan Raghunand, David L. Morse, Arig Ibrahim Hashim, Bonnie F. Sloane, Julie Dosescu, Denise J. Roe, Nathaniel D. Kirkpatrick, Brenda K. Baggett, Ian F. Robey
Supplementary Figures 1-5, Tables 1-3 from Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad579052566b51a803f3ca8f6b600ac
https://doi.org/10.1158/0008-5472.22376504
https://doi.org/10.1158/0008-5472.22376504
Autor:
Jianxin Mai, Izabela Podgorski, Michael L. Cher, Dora Cavallo-Medved, Mansoureh Sameni, Kamiar Moin, Bonnie F. Sloane, Julie Dosescu, Shiqing Yan, Bruce E. Linebaugh
Publikováno v:
Biological Sciences Publications
Tumor-stromal interactions induce expression of matrix metalloproteinases and serine proteases and, as shown recently, the cysteine protease cathepsin B. We speculate that such interactions upregulate the transcription factor Ets1, resulting in incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bfdce2d6c9d21aa3d470866a3091bf
https://doi.org/10.1016/j.semcancer.2004.08.001
https://doi.org/10.1016/j.semcancer.2004.08.001
Publikováno v:
Biological Sciences Publications
Cathepsin B and pro-urokinase plasminogen activator (pro-uPA) localize to the caveolae of HCT 116 human colorectal carcinoma cells, an association mediated by active K-RAS. In this study, we established a stable HCT 116 cell line with a gene encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876e13f1cdaf6b7a5168bd15ea484833
https://doi.org/10.1242/jcs.02278
https://doi.org/10.1242/jcs.02278
Autor:
Julie Dosescu, Mansoureh Sameni, Katherine Clark, Jennifer E. Koblinski, Kamiar Moin, Bonnie F. Sloane
Publikováno v:
Journal of Biological Chemistry. 277:32220-32227
Interactions of stromal and tumor cells with the extracellular matrix may regulate expression of proteases including the lysosomal proteases cathepsins B and D. In the present study, we determined whether the expression of these two proteases in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162840eac66bab2abc1b42ab2cac9fac
https://doi.org/10.1074/jbc.m204708200
https://doi.org/10.1074/jbc.m204708200
Autor:
John Tureaud, Julie Dosescu, Adip P.N. Majumdar, Latha Velusamy, Cheryl Neace, Yoram Elitsur, Jeffrey A. Moshier
Publikováno v:
Life Sciences. 65:1373-1380
H. pylori infection has been considered a risk factor for the development of gastric malignancy. Ornithine decarboxylase and tyrosine kinases activities are increased in patients with colon or esophageal cancer. In this study we compared the ODC and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77406e6af4335399e8c31a7229a8b048
https://doi.org/10.1016/s0024-3205(99)00376-8
https://doi.org/10.1016/s0024-3205(99)00376-8
Publikováno v:
Immunopharmacology. 38:279-285
Budesonide, a beta-adreno-receptor agonist, is comparable to corticosteroid in the treatment of patients with inflammatory bowel disease with the advantage of minimal side effect. Although the immunomodulatory effects of budesonide on the circulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be36cb69a60154ac627513760311225
https://doi.org/10.1016/s0162-3109(97)00090-8
https://doi.org/10.1016/s0162-3109(97)00090-8
Publikováno v:
Immunopharmacology. 35:247-253
Epidemiological studies have suggested an important immunomodulatory role for vitamin A and other related vitamin A compounds in adults and children. Although vitamin A is absorbed via the gastrointestinal tract, its affect on the gut mucosal immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e8278409e15bdbc8a589efd0bc16fd
https://doi.org/10.1016/s0162-3109(96)00152-x
https://doi.org/10.1016/s0162-3109(96)00152-x