Výsledky vyhledávání - "Julie D. Tobin"

Lack of efflux of diglycolic acid from proximal tubule cells leads to its accumulation and to toxicity of diethylene glycol

Autor: Julie D. Tobin, Corie N. Robinson, Elliot S. Luttrell-Williams, Greg M. Landry, Kenneth E. McMartin

Publikováno v: Toxicology Letters. 379:48-55

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ec43b11ccd210e3f245a5ada462aa1d
https://doi.org/10.1016/j.toxlet.2023.03.007

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Variable sensitivity to diethylene glycol poisoning is related to differences in the uptake transporter for the toxic metabolite diglycolic acid

Autor: Julie D. Tobin, Courtney N. Jamison, Corie N. Robinson, Kenneth E. McMartin

Publikováno v: Clinical Toxicology. 61:207-211

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7d2892ac3f05352c39ddbf8fd8266d6
https://doi.org/10.1080/15563650.2022.2163659

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Role of Plasma Membrane Dicarboxylate Transporters in the Uptake and Toxicity of Diglycolic Acid, a Metabolite of Diethylene Glycol, in Human Proximal Tubule Cells

Autor: Julie D, Tobin, Corie N, Robinson, Elliot S, Luttrell-Williams, Greg M, Landry, Donard, Dwyer, Kenneth E, McMartin

Publikováno v: Toxicological Sciences. 190:1-12

Diethylene glycol (DEG) mass poisonings have resulted from ingestion of pharmaceuticals mistakenly adulterated with DEG, typically leading to proximal tubular necrosis and acute kidney injury. The metabolite, diglycolic acid (DGA) accumulates greatly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99d595cd2fd87cbdca16b66e25a7947
https://doi.org/10.1093/toxsci/kfac091

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