Perspective on This Article from A Randomized Placebo-Controlled Prevention Trial of Aspirin and/or Resistant Starch in Young People with Familial Adenomatous Polyposis

Autor: John C. Mathers, Steffen Bülow, Robin K. S. Phillips, Julie Coaker, Hans F. A. Vasen, Gabriela Möslein, Eamonn R. Maher, Riccardo Fodde, D. Gareth Evans, Anthony Ellis, Diana Eccles, Malcolm G. Dunlop, Lucio Bertario, Faye Elliott, Pamela D. Chapman, D. Timothy Bishop, John Burn

Perspective on This Article from A Randomized Placebo-Controlled Prevention Trial of Aspirin and/or Resistant Starch in Young People with Familial Adenomatous Polyposis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbf9b5d97c88c0ab39e129c0b6d211a
https://doi.org/10.1158/1940-6207.22524728

A novel panel of short mononucleotide repeats linked to informative polymorphisms enabling effective high volume low cost discrimination between mismatch repair deficient and proficient tumours

Autor: Richard Gallon, Osagi Izuogu, Leonardo Maldaner Amorim, Mauro Santibanez-Koref, Mark J. Arends, John Burn, Julie Coaker, Lisa Redford, Michael S. Jackson, Ottie O’Brien, Harsh Sheth, Sira Moreno Laguna, John R. Tyson, Anca Oniscu, Stephanie Needham, Ghanim Alhilal, Angel Alonso, Iona Middleton

Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0203052 (2018)
Redford, L, Alhilal, G, Needham, S, O’Brien, O, Coaker, J, Tyson, J J, Maldaner Amorim, L, Middleton, I, Izuogu, O, Arends, M, Oniscu, A, Miguel Alonso, Á, Moreno Laguna, S, Gallon, R, Sheth, H, Santibanez-Koref, M, Jackson, M S & Burn, J 2018, ' A novel panel of short mononucleotide repeats linked to informative polymorphisms enabling effective high volume low cost discrimination between mismatch repair deficient and proficient tumours ', PLoS ONE . https://doi.org/10.1371/journal.pone.0203052

Somatic mutations in mononucleotide repeats are commonly used to assess the mismatch repair status of tumours. Current tests focus on repeats with a length above 15bp, which tend to be somatically more unstable than shorter ones. These longer repeats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8080997be3d9ce533f72fb3d276a8b4
http://europepmc.org/articles/PMC6114912?pdf=render

MONONUCLEAR PHAGOCYTE POPULATIONS IN THE TRANSPLANTED HUMAN LUNG1

Autor: Julie Coaker, Lisbet Sviland, A D Gascoigne, Debra S. Milne, Paul A. Corris, Thomas Ashcroft, Archie J. Malcolm

Publikováno v: Transplantation. 66:671-673

Background. Dendritic cells (DC) are essential for the development of alloreactivity, however, little has been published regarding the distribution and phenotype of these and related mononuclear cells in human lung transplantation. Methods. Lung froz

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https://doi.org/10.1097/00007890-199809150-00024

Intestinal tumorigenesis in the Apc1638N mouse treated with aspirin and resistant starch for up to 5 months

Autor: Riccardo Fodde, Slh Williamson, Kooshkghazi, John C. Mathers, John Burn, Alex Kartheuser, Julie Coaker

Publikováno v: Scopus-Elsevier

The Apc1638N mouse model, which carries a targeted mutant allele within the adenomatous polyposis (Apc) gene and develops intestinal tumours spontaneously, predominantly in the small bowel, was used to investigate the effects of two potential chemopr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d2b22f4e9d1821cb27688478d16668
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032903863&partnerID=MN8TOARS