Involving Patients and Clinicians in the Design of Wireframes for Cancer Medicines Electronic Patient Reported Outcome Measures in Clinical Care: Mixed Methods Study

Autor: Emma Dunlop, Aimee Ferguson, Tanja Mueller, Kelly Baillie, Jennifer Laskey, Julie Clarke, Amanj Kurdi, Ann Wales, Thomas Connolly, Marion Bennie

Publikováno v: JMIR Formative Research, Vol 7, p e48296 (2023)

BackgroundCancer treatment is a key component of health care systems, and the increasing number of cancer medicines is expanding the treatment landscape. However, evidence of the impact on patients has been focused more on chemotherapy toxicity and s

Externí odkaz: https://doaj.org/article/ae72889e782445c8ae392aae102e938b

Lessons from new mouse models of glycogen storage disease type 1a in relation to the time course and organ specificity of the disease

Autor: Gilles Mithieux, Julie Clar, Fabienne Rajas, Amandine Gautier-Stein

Publikováno v: Journal of Inherited Metabolic Disease
Journal of Inherited Metabolic Disease, Springer Verlag, 2015, 38 (3), pp.521-527. ⟨10.1007/s10545-014-9761-0⟩

Patients with glycogen storage diseases type 1 (GSD1) suffer from life-threatening hypoglycaemia, when left untreated. Despite an intensive dietary treatment, patients develop severe complications, such as liver tumors and renal failure, with aging.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f1d9be8d0ccd86098b4341eae37f80
https://doi.org/10.1007/s10545-014-9761-0

Hepatic lentiviral gene transfer prevents the long-term onset of hepatic tumours of glycogen storage disease type 1a in mice

Autor: Blandine Gri, Sophie Gaillard, Nicolas Ferry, Julie Clar, A. Stefanutti, Alison Creneguy, Tuan Huy Nguyen, Fabienne Rajas, Elodie Mutel, Gilles Mithieux, Olivier Beuf

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2015, 24 (8), pp.2287-2296. ⟨10.1093/hmg/ddu746⟩
Human Molecular Genetics, 2015, 24 (8), pp.2287-2296. ⟨10.1093/hmg/ddu746⟩

Glycogen storage disease type 1a (GSD1a) is a rare disease due to the deficiency in the glucose-6-phosphatase (G6Pase) catalytic subunit (encoded by G6pc), which is essential for endogenous glucose production. Despite strict diet control to maintain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6718902b4472ba0c5f204f5d4bc919
https://www.hal.inserm.fr/inserm-01350897/document

Influence des régimes alimentaires sur le développement des tumeurs hépatiques dans un modèle de stéatose hépatique chez la souris

Autor: Sophie Gaillard, Olivier Beuf, Gilles Mithieux, Fabienne Rajas, Blandine Gri, Julie Clar, Frank Pilleul

Publikováno v: Annales d\textquoterightEndocrinologie
Annales d\textquoterightEndocrinologie, 2013, Unknown, Unknown Region. pp.160, ⟨10.1016/j.ando.2013.03.023⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d243e335ea108deb96d2bb1ced87e7d
https://hal.archives-ouvertes.fr/hal-01922777

Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial

Autor: Laura Williams, Charlotte L. Hall, Sue Brown, Boliang Guo, Marilyn James, Matilde Franceschini, Julie Clarke, Kim Selby, Hena Vijayan, Neeta Kulkarni, Nikki Brown, Kapil Sayal, Chris Hollis, Madeleine J. Groom

Publikováno v: Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-18 (2021)

Abstract Background Medication for attention deficit hyperactivity disorder (ADHD) should be closely monitored to ensure optimisation. There is growing interest in using computerised assessments of ADHD symptoms to support medication monitoring. The

Externí odkaz: https://doaj.org/article/d7127e97aa464028a2db8049e3a83cbc