Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julie C. Johnston"'
Autor:
Jason Heth, Deborah A. Cory-Slechta, Paul M. McCray, Beverly L. Davidson, Howard J. Federoff, Andrew I. Brooks, Julie C. Johnston, Colleen S. Stein, Sybille L. Sauter, Stephanie M. Hughes
Publikováno v:
Proceedings of the National Academy of Sciences. 99:6216-6221
Gene transfer vectors based on lentiviruses can transduce terminally differentiated cells in the brain; however, their ability to reverse established behavioral deficits in animal models of neurodegeneration has not previously been tested. When recom
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1027
Adeno-associated viral vectors have proven to be excellent gene delivery vehicles for somatic overexpression. These viral vectors can efficiently and selectively target the liver, which plays a central role in lipoprotein metabolism. Both liver-expre
Autor:
D'Ann Rochon, Julie C. Johnston
Publikováno v:
Virology. 221(1):232-239
The importance of codon context and leader length in the translational regulation of p20 and p21 from the bifunctional 0.9-kb subgenomic mRNA of cucumber necrosis virus was investigated. Nucleotide substitutions introduced into the −3 and +4 positi
Autor:
Julie C. Johnston, D'Ann Rochon
Publikováno v:
Virology. 214(1):100-109
Sequences comprising the core promoter for the cucumber necrosis virus (CNV) 0.9-kb subgenomic RNA have been determined using deletion analysis and site-directed mutagenesis. The deletion studies indicate that the promoter lies within a region locate
Publikováno v:
Canadian Journal of Plant Pathology. 13:142-154
(1991). Molecular analysis of the cucumber necrosis virus genome. Canadian Journal of Plant Pathology: Vol. 13, No. 2, pp. 142-154.
Autor:
Sybille L. Sauter, Vladimir Slepushkin, Shaf Keshavjee, Thomas W. Dubensky, Beverly L. Davidson, Doug J. Jolly, Julie C. Johnston, Paul B. McCray, Guoshun Wang, Joseph Zabner
Publikováno v:
The Journal of clinical investigation. 104(11)
Several problems limit the application of gene transfer to correct the cystic fibrosis (CF) Cl– transport defect in airway epithelia. These include inefficient transduction with vectors applied to the apical surface, a low rate of division by airwa
Autor:
Melanie G. Ter Borg, Tim L. Sit, Emile Frison, Morven A. McLean, D'Ann Rochon, Julie C. Johnston
Publikováno v:
Virology. 206(1)
A series of frameshift, deletion, and inversion mutations were made in the coat protein (CP) gene of the icosahedralcucumber necrosis tombusvirus (CNV) to investigate the role of the CP protruding (P) domain in the production of virus particles and,
Autor:
Julie C. Johnston, D'Ann Rochon
Publikováno v:
The Journal of general virology. 71
The in vitro translation products directed by cucumber necrosis virus (CNV) RNA were analysed in both rabbit reticulocyte lysate and wheatgerm extract cell-free translation systems. In rabbit reticulocyte lysates, one major protein of approximate Mr
Autor:
Christian Duhme, Regis Doyonnas, Carmen C.M. Chan, Julie C. Johnston, Helen Merkens, Kelly M. McNagny
Publikováno v:
Experimental Hematology. 28:54
CD34 is a cell surface sialomucin expressed by hematopoietic precursors and vascular endothelia. Despite its widespread use as a marker of early hematopoietic precursors, little is known about its function on these cells and deletion of the encoding