Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Julie C. Barnes"'
1
Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species
Autor: Jane Z. Reed, Julie C. Barnes, Denis Fourches, Paul Bradley, Nicola C. Day, Alexander Tropsha
Publikováno v: Chemical Research in Toxicology. 23:171-183
Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee943e427dcb7354d8a2323375fb472
https://doi.org/10.1021/tx900326k
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2
Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation
Autor: Hilkka Soininen, Nicola C. Day, Simon Lovestone, Iwona Kłoszewska, Patrizia Mecocci, Christian Spenger, Lars-Olof Wahlund, Joanna Riddoch-Contreras, Ines Greco, Julie C. Barnes, Andrew Simmons, Bruno Vellas, Jane Z. Reed, Magda Tsolaki
Publikováno v: Journal of Translational Medicine
Journal of Translational Medicine, 2012, 10 (1), pp.217. ⟨10.1186/1479-5876-10-217⟩
Journal of Translational Medicine, BioMed Central, 2012, 10 (1), pp.217. ⟨10.1186/1479-5876-10-217⟩
Journal of Translational Medicine, Vol 10, Iss 1, p 217 (2012)
Background Alzheimer’s Disease (AD) is the most widespread form of dementia in the elderly but despite progress made in recent years towards a mechanistic understanding, there is still an urgent need for disease modification therapy and for early d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e9fbcd602d69abda7f7fade524e533
https://www.hal.inserm.fr/inserm-00758566/file/1479-5876-10-217.pdf
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4
Attenuation of scopolamine-induced spatial memory deficits in the rat by cholinomimetic and non-cholinomimetic drugs using a novel task in the 12-arm radial maze
Autor: Julie C. Barnes, Robert P. Dennes
Publikováno v: Psychopharmacology. 111(4)
The effects of cholinomimetic and non-cholinomimetic agents on spatial memory using a novel task in the 12-arm radial maze were investigated. The task was designed to reduce the tendency to use non-spatial strategies. Animals were repeatedly trained
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd1f7889f82bf04c425b88001d456b4
https://pubmed.ncbi.nlm.nih.gov/7870985
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6
Modulation of dopamine function by glycine in the nucleus accumbens of the brain of the rat
Autor: Robert J. Naylor, Julie C. Barnes, Brenda Costall
Publikováno v: Neuropharmacology. 25:1347-1351
The effects of glycine on the phasic changes in locomotor activity in the rat, caused by a persistent infusion of dopamine (DA) into the nucleus accumbens (ACB) were investigated. Dopamine (25 μg/24 hr), infused into the nucleus accumbens for 13 day
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e31f1bffa1f4c483010ad8a91da5a52
https://doi.org/10.1016/0028-3908(86)90107-3
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7
Ketotifen can antagonise changes in sensitivity of cerebral dopamine receptors: Behavioural correlates in rodent and primate
Autor: Julie C. Barnes, N.J.G. Barnes, Robert J. Naylor, Nicholas M. Barnes, Brenda Costall, A.M. Domeney
Publikováno v: Neuropharmacology. 26:693-700
Rats preselected as “low responders” to the hyperactivity-inducing action of (−) N - n -propylnorapomorphine [(−)NPA] responded to an infusion of dopamine into the nucleus accumbens (25 μg/24hr for 13 days) with hyperactivity during the infu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e61262899a85f8930265476d9586d81
https://doi.org/10.1016/0028-3908(87)90229-2
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8
Lithium and bupropion antagonise the phasic changes in locomotor activity caused by dopamine infused into the rat nucleus accumbens
Autor: Robert J. Naylor, Brenda Costall, A.M. Domeney, Julie C. Barnes
Publikováno v: Psychopharmacology. 89(3)
Dopamine infused persistently (25 micrograms/24 h for 13 days) into the nucleus accumbens of rat brain caused phasic increases in spontaneous locomotor activity during the period of infusion. This phasic responding was prevented by lithium administer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629ebed81cd960faedb57dcd68cc6d31
https://pubmed.ncbi.nlm.nih.gov/3088656
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9
The functional anatomy of imagining and perceiving colour
Autor: Edward T. Bullmore, Michael Brammer, Peter W.R. Woodruff, Declan J. McKeefry, Andrew Simmons, RJ Howard, Y Ha, Steven Williams, A.S. David, Dominic Ffytche, Julie C. Barnes
Publikováno v: King's College London
ResearcherID
Scopus-Elsevier
We report two functional magnetic resonance imaging experiments which reveal similarities and differences between perceptual and imaginal networks within the single visual submodality of colour. The first experiment contrasted viewing of a coloured a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c266ab627669a611d428853f96e04580
https://kclpure.kcl.ac.uk/portal/en/publications/the-functional-anatomy-of-imagining-and-perceiving-colour(1098a5a3-c8c7-456b-95cd-5a7ddf6e89fc).html
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