Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julie C Necarsulmer"'
Autor:
Julie C Necarsulmer, Jeremy M Simon, Baggio A Evangelista, Youjun Chen, Xu Tian, Sara Nafees, Ariana B Marquez, Huijun Jiang, Ping Wang, Deepa Ajit, Viktoriya D Nikolova, Kathryn M Harper, J Ashley Ezzell, Feng-Chang Lin, Adriana S Beltran, Sheryl S Moy, Todd J Cohen
Publikováno v:
eLife, Vol 12 (2023)
TDP-43 proteinopathies including frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative disorders characterized by aggregation and mislocalization of the nucleic acid-binding protein TDP-43 and subseque
Externí odkaz:
https://doaj.org/article/1ef60b65b631406abd7b36cb7384d395
Autor:
Jodi A. Morrissey, Erin Bigus, Julie C. Necarsulmer, Vinay Srinivasan, Katie Peppercorn, Daniel J. O’Leary, Bruce G. Mockett, Warren P. Tate, Stephanie M. Hughes, Karen D. Parfitt, Wickliffe C. Abraham
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Secreted amyloid precursor protein-alpha (sAPPα), generated by enzymatic processing of the APP, possesses a range of neurotrophic and neuroprotective properties and plays a critical role in the molecular mechanisms of memory and learning. One of the
Externí odkaz:
https://doaj.org/article/17c333daa54044fa944310ae25f4bb81
Autor:
Heather A. Baldwin, Pyry P. Koivula, Julie C. Necarsulmer, Keith W. Whitaker, Brandon K. Harvey
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Parkinson's disease is a progressive neurological disorder, marked by the loss of dopaminergic neurons in the nigrostriatal pathway that leads to abnormal gait, rigidity, slowness of movement, and tremor. The ability to recapitulate and measure the n
Externí odkaz:
https://doaj.org/article/b25aa2fccd334d909273473e8d43ad75
Autor:
Baggio A. Evangelista, Shannon R. Cahalan, Joey V. Ragusa, Angie Mordant, Julie C. Necarsulmer, Robert J. Perna, Tejazaditya Ajit, Kristen White, Natalie K. Barker, Xu Tian, Sarah Cohen, Rick Meeker, Laura E. Herring, Todd J. Cohen
Publikováno v:
iScience. 26:106645
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72d6d1895b87ebfd0a6669d5023f94ce
https://doi.org/10.1016/j.isci.2023.106645
https://doi.org/10.1016/j.isci.2023.106645
Autor:
Alexander F. Hoffman, Julie C. Necarsulmer, Bruce T. Hope, Agustin Zapata, Reinis Svarcbahs, Carl R. Lupica, Lamarque M. Coke, Andrew M. Wright, Brandon K. Harvey, James Pickel, Christopher T. Richie
Publikováno v:
eNeuro
The orbitofrontal cortex (OFC) is a brain region involved in higher-order decision-making. Rodent studies show that cocaine self-administration (CSA) reduces OFC contribution to goal-directed behavior and behavioral strategies to avoid drug intake. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f1031a6c47ca4ecac7006492b66070
https://doi.org/10.1523/eneuro.0017-21.2021
https://doi.org/10.1523/eneuro.0017-21.2021
Autor:
Julie C. Necarsulmer, Heather A. Baldwin, YaJun Zhang, Leslie R. Whitaker, Kai Wang, Bruce T. Hope, Jeffrey C. Smith, Josh. J. Hinkle, Wenzhi Sun, Lowella V. Fortuno, Pyry Koivula, Brandon K. Harvey, Na Ji, Mark J. Henderson, Keith W. Whitaker, Christopher T. Richie, Jim Pickel
Publikováno v:
Journal of Neuroscience Methods. 284:1-14
Background The use of genetically-encoded fluorescent reporters is essential for the identification and observation of cells that express transgenic modulatory proteins. Near-infrared (NIR) fluorescent proteins have superior light penetration through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ca7662f45411be6829eb687dc402dc
https://doi.org/10.1016/j.jneumeth.2017.03.020
https://doi.org/10.1016/j.jneumeth.2017.03.020
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Parkinson's disease is a progressive neurological disorder, marked by the loss of dopaminergic neurons in the nigrostriatal pathway that leads to abnormal gait, rigidity, slowness of movement, and tremor. The ability to recapitulate and measure the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63283c123e4d0107b3becf9431fe0f07
https://doi.org/10.3727/096368916x693059
https://doi.org/10.3727/096368916x693059
Autor:
Lowella V. Fortuno, Susanne Bäck, Bruce T. Hope, YaJun Zhang, C. Grace Yeh, Jenni E. Anttila, Alexander F. Hoffman, Leslie R. Whitaker, Charles E. Spivak, Emily J. Heathward, Pyry Koivula, Carlos A. Mejias-Aponte, Mikko Airavaara, Suzanne M. Underhill, Heather A. Baldwin, F. Kent Hamra, Andrii Domanskyi, Carl R. Lupica, Brandon K. Harvey, Julie C. Necarsulmer, Morgan D. Spencer, James Pickel, Christopher T. Richie, Susan G. Amara, Lamarque M. Coke
Publikováno v:
Neuron. 102(1)
Historically, the rat has been the preferred animal model for behavioral studies. Limitations in genome modification have, however, caused a lag in their use compared to the bevy of available transgenic mice. Here, we have developed several transgeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b964f845c1ad8e3b45a7e2bb78fe86
https://pubmed.ncbi.nlm.nih.gov/30792150
https://pubmed.ncbi.nlm.nih.gov/30792150
Autor:
Brandon L. Warren, Bruce T. Hope, Mark J. Henderson, Lowella V. Fortuno, Raffaello Cimbro, Pyry Koivula, Veronica J. Wallace, Julie C. Necarsulmer, F. Javier Rubio, Lindsay M. DeBiase, Brandon K. Harvey
Publikováno v:
Cellular and molecular neurobiology. 37(8)
Microparticles have potential as neuron-specific delivery platforms and devices with many applications in neuroscience, pharmacology and biomedicine. To date, most literature suggests that neurons are not phagocytic cells capable of internalizing mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0511a499b2f15c26e11d5dc9dc71cd7
https://pubmed.ncbi.nlm.nih.gov/28260198
https://pubmed.ncbi.nlm.nih.gov/28260198
Autor:
Jeffrey C. Smith, Julie C. Necarsulmer, Nathan J. Marchant, Leslie R. Whitaker, Carlos A. Mejias-Aponte, Erin J. Campbell, Geoffrey Schoenbaum, Melissa J. Sharpe, Yajun J. Zhang, Brandon K. Harvey, Pyry Koivula, Yavin Shaham, Marisela Morales, James Pickel, Yael Niv, Christopher T. Richie
Publikováno v:
Current Biology, 27(14), 2089-2100.e5. Cell Press
Sharpe, M J, Marchant, N J, Whitaker, L R, Richie, C T, Zhang, Y J, Campbell, E J, Koivula, P P, Necarsulmer, J C, Mejias-Aponte, C, Morales, M, Pickel, J, Smith, J C, Niv, Y, Shaham, Y, Harvey, B K & Schoenbaum, G 2017, ' Lateral Hypothalamic GABAergic Neurons Encode Reward Predictions that Are Relayed to the Ventral Tegmental Area to Regulate Learning ', Current Biology, vol. 27, no. 14, pp. 2089-2100.e5 . https://doi.org/10.1016/j.cub.2017.06.024
Sharpe, M J, Marchant, N J, Whitaker, L R, Richie, C T, Zhang, Y J, Campbell, E J, Koivula, P P, Necarsulmer, J C, Mejias-Aponte, C, Morales, M, Pickel, J, Smith, J C, Niv, Y, Shaham, Y, Harvey, B K & Schoenbaum, G 2017, ' Lateral Hypothalamic GABAergic Neurons Encode Reward Predictions that Are Relayed to the Ventral Tegmental Area to Regulate Learning ', Current Biology, vol. 27, no. 14, pp. 2089-2100.e5 . https://doi.org/10.1016/j.cub.2017.06.024
Eating is a learned process. Our desires for specific foods arise through experience. Both electrical stimulation and optogenetic studies have shown that increased activity in the lateral hypothalamus (LH) promotes feeding. Current dogma is that thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d44da9033d314ec9b54b0e923fed960
https://doi.org/10.1016/j.cub.2017.06.024
https://doi.org/10.1016/j.cub.2017.06.024