Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Julie C Carrier"'
Publikováno v:
Heliyon, Vol 2, Iss 5 (2016)
The Hedgehog (HH) signaling pathway is involved in the maintenance of numerous cell types both during development and in the adult. Often deregulated in cancers, its involvement in colorectal cancer has come into view during the last few years, altho
Externí odkaz:
https://doaj.org/article/1b2713d2e845413c9950782f40d52a5a
Autor:
Marie-Josée Langlois, Sébastien Bergeron, Gérald Bernatchez, François Boudreau, Caroline Saucier, Nathalie Perreault, Julie C Carrier, Nathalie Rivard
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15742 (2010)
The PTEN phosphatase acts on phosphatidylinositol 3,4,5-triphosphates resulting from phosphatidylinositol 3-kinase (PI3K) activation. PTEN expression has been shown to be decreased in colorectal cancer. Little is known however as to the specific cell
Externí odkaz:
https://doaj.org/article/33148b247fec4292966d180909d6adc0
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1765
Proximal promoters are located upstream of the transcription start sites of genes, and they contain regulatory sequences on which bind different transcription factors for promoting colorectal cancer progression. Here we describe the comprehensive met
The G protein-coupled P2Y₆ receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis
Autor:
Morgane, Placet, Guillaume, Arguin, Caroline M, Molle, Jean-Philippe, Babeu, Christine, Jones, Julie C, Carrier, Bernand, Robaye, Sameh, Geha, Francois, Boudreau, Fernand-Pierre, Gendron
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1864(5 Pt)
Colorectal tumors are immersed in an array of tumor-promoting factors including extracellular nucleotides such as uridine 5'‑diphosphate (UDP). UDP is the endogenous agonist of the G protein-coupled P2Y
Autor:
Veronique Giroux, André C. Carpentier, Julie C. Carrier, Thomas Lassalle, Nathalie Rivard, Gérald Bernatchez
Publikováno v:
Carcinogenesis. 34(10)
The estrogen-related receptor alpha (ERRα) is a nuclear receptor that acts primarily as a regulator of metabolic processes, particularly in tissues subjected to high-energy demand. In addition to its control of energy metabolism and mitochondrial bi
Autor:
Julie C. Carrier, Yannick D. Benoit, Taoufik Khalfaoui, Gérald Bernatchez, Nuria Basora, Jean-François Groulx, Jean-François Beaulieu
Recently, autophagy has been found to be strongly activated in colon cancer cells, but few studies have addressed the normal colon mucosa. The aim of this study was to characterize autophagy in normal human intestinal cells. We used the expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9095414b72b64639b3006ee3be542673
https://europepmc.org/articles/PMC3427255/
https://europepmc.org/articles/PMC3427255/
Autor:
Eric Tremblay, Nuria Basora, Julie C. Carrier, Yannick D. Benoit, Lorraine J. Gudas, Taoufik Khalfaoui, Jean-François Beaulieu, Manon Lepage
Publikováno v:
Journal of Cell Science.
The crypt–villus axis constitutes the functional unit of the small intestine, where mature absorptive cells are confined to the villi, and stem cells and transit amplifying and differentiating cells are restricted to the crypts. The polycomb group
Autor:
Marie-Josée Langlois, Nathalie Perreault, Sebastien A. B. Roy, Julie C. Carrier, François Boudreau, Nathalie Rivard
Publikováno v:
World journal of gastroenterology. 18(14)
To investigate the impact of phosphatase and tensin homolog (Pten) in the specification of intestinal enteroendocrine subpopulations.Using the Cre/loxP system, a mouse with conditional intestinal epithelial Pten deficiency was generated. Pten mutant
Autor:
Julie C. Carrier, Yuji Mishina, Nathalie Perreault, Jessica Gagné-Sansfaçon, Philippe Sarret, Faiza Maloum, Klaus H. Kaestner, Joannie M. Allaire, Karine Belleville, Evelyne Roy, Jean Morisset
Bone morphogenetic protein (BMP) signaling within the gastrointestinal tract is complex. BMP ligands and their receptors are expressed in both epithelial and mesenchymal compartments, suggesting bidirectional signaling between these two entities. Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063d3ccd27905e38e8ab904b773e39f3
https://europepmc.org/articles/PMC3119118/
https://europepmc.org/articles/PMC3119118/
Publikováno v:
Neuroscience. 184
It is strongly suggested that estrogen plays a key role in pain modulation. Estrogen's effects are mediated mainly by two receptors, ERα and ERβ. However, the specific role of these receptors is still not clear. In this study, the involvement of bo