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Bringing together scientific disciplines for collaborative undertakings: a vision for advancing the adverse outcome pathway framework

Publikováno v: International Journal of Radiation Biology
International Journal of Radiation Biology, Informa Healthcare, 2021, 97 (4), pp.431-441. ⟨10.1080/09553002.2021.1884314⟩

International audience; Background: Decades of research to understand the impacts of various types of environmental occupational and medical stressors on human health have produced a vast amount of data across many scientific disciplines. Organizing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6e0fc89815d0a52c9469f8301e1c31
https://doi.org/10.1080/09553002.2021.1884314

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Adverse outcome pathway: a path toward better data consolidation and global co-ordination of radiation research

Autor: Vinita Chauhan, Danielle Beaton, Nobuyuki Hamada, Ruth Wilkins, Julie Burtt, Julie Leblanc, Donald Cool, Jacqueline Garnier-Laplace, Dominique Laurier, Yevgeniya Le, Yukata Yamada, Knut Erik Tollefsen

Publikováno v: International journal of radiation biology. 98(12)

The purpose of toxicology is to protect human health and the environment. To support this, the Organisation for Economic Co-operation and Development (OECD), operating via its Extended Advisory Group for Molecular Screening and Toxicogenomics (EAGMST

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530c9475654cb4a77dacae056762960c
https://pubmed.ncbi.nlm.nih.gov/34919011

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COHERE - strengthening cooperation within the Canadian government on radiation research

Autor: Julie Leblanc, Rachel Lane, Ruth C. Wilkins, Kiza Sauvé, Debora Quayle, Kristi Randhawa, Vinita Chauhan, Julie Burtt, Baki Sadi

Publikováno v: International journal of radiation biology. 97(9)

PURPOSE Canadian Organization on Health Effects from Radiation Exposure (COHERE) is a government initiative to better understand biological and human health risks from ionizing radiation exposures relevant to occupational and environmental settings (

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https://pubmed.ncbi.nlm.nih.gov/34133252

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Projecting thyroid cancer risk to the general public from radiation exposure following hypothetical severe nuclear accidents in Canada

Autor: Andrew McAllister, Lauren Bergman, Melanie Rickard, Julie Burtt, Lydia B. Zablotska

Publikováno v: Journal of radiological protection : official journal of the Society for Radiological Protection, vol 40, iss 4

Author(s): Burtt, Julie Jane; Rickard, Melanie; McAllister, Andrew; Bergman, Lauren; Zablotska, Lydia B | Abstract: IntroductionA robust emergency management framework can limit radiation exposures and effectively minimize the potentially devastating

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https://escholarship.org/uc/item/2174g745

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Is there a role for the adverse outcome pathway framework to support radiation protection?

Publikováno v: International Journal of Radiation Biology. 95:225-232

In 2012, the Organization for Economic Cooperation and Development (OECD) formally launched the Adverse Outcome Pathway (AOP) Programme. The AOP framework has the potential for predictive utility in identifying early biological endpoints linked to ad

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https://doi.org/10.1080/09553002.2019.1532617

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Radiation Biology and Its Role in the Canadian Radiation Protection Framework

Autor: Julie Burtt, Julie Leblanc

Publikováno v: Health physics. 117(3)

The linear no-threshold (linear-non-threshold) model is a dose-response model that has long served as the foundation of the international radiation protection framework, which includes the Canadian regulatory framework. Its purpose is to inform the c

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https://pubmed.ncbi.nlm.nih.gov/32118682

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Non-targeted effects and radiation-induced carcinogenesis: a review

Autor: Robert M. Lafrenie, Patsy Thompson, Julie Burtt

Publikováno v: Journal of radiological protection : official journal of the Society for Radiological Protection. 36(1)

Exposure to ionising radiation is clearly associated with an increased risk of developing some types of cancer. However, the contribution of non-targeted effects to cancer development after exposure to ionising radiation is far less clear. The curren

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https://pubmed.ncbi.nlm.nih.gov/26910391

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Use of a Weight of Evidence Approach to Determine the Likelihood of Adverse Effects on Human Health from the Presence of Uranium Facilities in Port Hope, Ontario

Autor: Michael Ilin, Patsy Thompson, Pascale Reinhardt, Julie Burtt, Rachel Lane, Marcelle Phaneuf

Publikováno v: Journal of Environmental Protection. :1149-1161

The radium and uranium processing industry exists in Port Hope, Ontario, since 1932. Between 1932 and 1966, most of the waste material from these industries was deposited throughout the town. During these years, waste management practices did not pre

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https://doi.org/10.4236/jep.2011.29134

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