Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Julie Boucau"'
Autor:
Eike-Christian Wamhoff, Larance Ronsard, Jared Feldman, Grant A. Knappe, Blake M. Hauser, Anna Romanov, James Brett Case, Shilpa Sanapala, Evan C. Lam, Kerri J. St. Denis, Julie Boucau, Amy K. Barczak, Alejandro B. Balazs, Michael S. Diamond, Aaron G. Schmidt, Daniel Lingwood, Mark Bathe
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize antigens and enhance humoral immunity through multivalent antigen display. However, P-VLPs are thymus-dependent antigens that are themselves immunogenic and
Externí odkaz:
https://doaj.org/article/a903d94958bc48e7ac6e79ace0aa2f9a
Autor:
Charul Jani, Sydney L. Solomon, Joshua M. Peters, Stephanie C. Pringle, Amelia E. Hinman, Julie Boucau, Bryan D. Bryson, Amy K. Barczak
Publikováno v:
mSystems, Vol 8, Iss 4 (2023)
ABSTRACT Tuberculosis (TB), caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb), is a global health threat. Targeting host pathways that modulate protective or harmful components of inflammation has been proposed as a therapeutic stra
Externí odkaz:
https://doaj.org/article/f2cc880adb9f4f9caff74342e55a3c54
Autor:
Ryan P. McNamara, Jenny S. Maron, Julie Boucau, Vicky Roy, Nicholas E. Webb, Harry L. Bertera, Amy K. Barczak, The Positives Study Staff, Nicholas Franko, Jennifer K. Logue, Megan Kemp, Jonathan Z. Li, Ling Zhou, Ching-Lin Hsieh, Jason S. McLellan, Mark J. Siedner, Michael S. Seaman, Jacob E. Lemieux, Helen Y. Chu, Galit Alter
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT While immune correlates against SARS-CoV-2 are typically defined at peak immunogenicity following vaccination, immunologic responses that expand selectively during the anamnestic response following infection can provide mechanistic and detai
Externí odkaz:
https://doaj.org/article/3965379e79f746fcbfe4f35aa08c453f
Autor:
Hugues Allard-Chamard, Naoki Kaneko, Alice Bertocchi, Na Sun, Julie Boucau, Hsiao-Hsuan Kuo, Jocelyn R. Farmer, Cory Perugino, Vinay S. Mahajan, Samuel J.H. Murphy, Katherine Premo, Thomas Diefenbach, Musie Ghebremichael, Grace Yuen, Alekhya Kotta, Zafer Akman, Mathias Lichterfeld, Bruce D. Walker, Xu G. Yu, Masafumi Moriyama, Takashi Maehara, Seiji Nakamura, John H. Stone, Robert F. Padera, Shiv Pillai
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112630- (2023)
Summary: Although therapeutic B cell depletion dramatically resolves inflammation in many diseases in which antibodies appear not to play a central role, distinct extrafollicular pathogenic B cell subsets that accumulate in disease lesions have hithe
Externí odkaz:
https://doaj.org/article/f6449a71ead94ed7a5350e782a784b4a
Autor:
Michael S. Seaman, Mark J. Siedner, Julie Boucau, Christy L. Lavine, Fadi Ghantous, May Y. Liew, Josh I. Mathews, Arshdeep Singh, Caitlin Marino, James Regan, Rockib Uddin, Manish C. Choudhary, James P. Flynn, Geoffrey Chen, Ashley M. Stuckwisch, Taryn Lipiner, Autumn Kittilson, Meghan Melberg, Rebecca F. Gilbert, Zahra Reynolds, Surabhi L. Iyer, Grace C. Chamberlin, Tammy D. Vyas, Jatin M. Vyas, Marcia B. Goldberg, Jeremy Luban, Jonathan Z. Li, Amy K. Barczak, Jacob E. Lemieux
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
Protective immunity against SARS-CoV-2 infection after COVID-19 vaccination may differ by variant. We enrolled vaccinated (n = 39) and unvaccinated (n = 11) individuals with acute, symptomatic SARS-CoV-2 Delta or Omicron infection and performed SARS-
Externí odkaz:
https://doaj.org/article/f38fc7bc66254b8ba43336ada4cb99c2
Autor:
Mark J. Siedner, Julie Boucau, Rebecca F. Gilbert, Rockib Uddin, Jonathan Luu, Sebastien Haneuse, Tammy Vyas, Zahra Reynolds, Surabhi Iyer, Grace C. Chamberlin, Robert H. Goldstein, Crystal M. North, Chana A. Sacks, James Regan, James P. Flynn, Manish C. Choudhary, Jatin M. Vyas, Amy K. Barczak, Jacob E. Lemieux, Jonathan Z. Li
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Isolation guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are largely derived from data collected prior to the emergence of the delta variant. We followed a cohort of ambulatory patients with postvaccination breakthrough S
Externí odkaz:
https://doaj.org/article/90bbd3e2fac74e5f9bf5980bad4e7da2
Autor:
Rujapak Sutiwisesak, Nathan D Hicks, Shayla Boyce, Kenan C Murphy, Kadamba Papavinasasundaram, Stephen M Carpenter, Julie Boucau, Neelambari Joshi, Sylvie Le Gall, Sarah M Fortune, Christopher M Sassetti, Samuel M Behar
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1009000 (2020)
CD8 T cells provide limited protection against Mycobacterium tuberculosis (Mtb) infection in the mouse model. As Mtb causes chronic infection in mice and humans, we hypothesize that Mtb impairs T cell responses as an immune evasion strategy. TB10.4 i
Externí odkaz:
https://doaj.org/article/ba98c37fa02f4bdd9e8bb26ea48d0589
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008442 (2020)
Latency reversal agents (LRA) variably induce HIV re-expression in CD4 T cells but reservoirs are not cleared. Whether HIV epitope presentation is similar between latency reversal and initial infection of CD4 T cells is unknown yet crucial to define
Externí odkaz:
https://doaj.org/article/1fd33fa231404c10a62066f45a8acdcf
Publikováno v:
ACS Applied Materials & Interfaces. 14:42483-42493
Microbial adhesion and contamination on shared surfaces can lead to life-threatening infections with serious impacts on public health, economy, and clinical practices. The traditional use of chemical disinfectants for sanitization of surfaces, howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794dfd2c15c75f7cda859110173a43fd
https://doi.org/10.1021/acsami.2c11915
https://doi.org/10.1021/acsami.2c11915
Autor:
Julie Boucau, Rockib Uddin, Caitlin Marino, James Regan, James P Flynn, Manish C Choudhary, Geoffrey Chen, Ashley M Stuckwisch, Josh Mathews, May Y Liew, Arshdeep Singh, Zahra Reynolds, Surabhi L Iyer, Grace C Chamberlin, Tammy D Vyas, Jatin M Vyas, Sarah E Turbett, Jonathan Z Li, Jacob E Lemieux, Amy K Barczak, Mark J Siedner
Publikováno v:
Clinical Infectious Diseases. 76:e526-e529
We enrolled 7 individuals with recurrent symptoms or antigen test conversion following nirmatrelvir-ritonavir treatment. High viral loads (median 6.1 log10 copies/mL) were detected after rebound for a median of 17 days after initial diagnosis. Three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::086f5e25d45f26ff2c4fb82aabd4f6f4
https://doi.org/10.1093/cid/ciac512
https://doi.org/10.1093/cid/ciac512