Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Julie Bossuyt"'
Autor:
Bence Hegyi, Juliana Mira Hernandez, Christopher Y. Ko, Junyoung Hong, Erin Y. Shen, Emily R. Spencer, Daria Smoliarchuk, Manuel F. Navedo, Donald M. Bers, Julie Bossuyt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 23 (2022)
Background The pathobiology of heart failure with preserved ejection fraction (HFpEF) is still poorly understood, and effective therapies remain limited. Diabetes and mineralocorticoid excess are common and important pathophysiological factors that m
Externí odkaz:
https://doaj.org/article/f894cdcd88b24aaf9dd73caf14ff55d9
Autor:
Julie Bossuyt, Johanna M. Borst, Marie Verberckmoes, Logan R. J. Bailey, Donald M. Bers, Bence Hegyi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 19 (2022)
Background Structural and electrophysiological remodeling characterize heart failure (HF) enhancing arrhythmias. PKD1 (protein kinase D1) is upregulated in HF and mediates pathological hypertrophic signaling, but its role in K+ channel remodeling and
Externí odkaz:
https://doaj.org/article/a20535135f97454bbf42416f5160752a
Autor:
Yankun Lyu, Phung N. Thai, Lu Ren, Valeriy Timofeyev, Zhong Jian, Seojin Park, Kenneth S. Ginsburg, James Overton, Julie Bossuyt, Donald M. Bers, Ebenezer N. Yamoah, Ye Chen-Izu, Nipavan Chiamvimonvat, Xiao-Dong Zhang
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103624- (2022)
Summary: The mammalian heart beats incessantly with rhythmic mechanical activities generating acids that need to be buffered to maintain a stable intracellular pH (pHi) for normal cardiac function. Even though spatial pHi non-uniformity in cardiomyoc
Externí odkaz:
https://doaj.org/article/71ec355c18ca46c0abb871b3e9983834
Autor:
Gopireddy R. Reddy, Lu Ren, Phung N. Thai, Jessica L. Caldwell, Manuela Zaccolo, Julie Bossuyt, Crystal M. Ripplinger, Yang K. Xiang, Madeline Nieves-Cintrón, Nipavan Chiamvimonvat, Manuel F. Navedo
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103693- (2022)
Summary: Sinoatrial node (SAN) cells are the pacemakers of the heart. This study describes a method for culturing and infection of adult mouse SAN cells with FRET-based biosensors that can be exploited to examine signaling events. SAN cells cultured
Externí odkaz:
https://doaj.org/article/a4901bdc385443a6b47fa18fb6c488d0
Autor:
Jessica I Gold, Jeffrey S Martini, Jonathan Hullmann, Erhe Gao, J Kurt Chuprun, Linda Lee, Douglas G Tilley, Joseph E Rabinowitz, Julie Bossuyt, Donald M Bers, Walter J Koch
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57324 (2013)
G protein-Coupled Receptors (GPCRs) kinases (GRKs) play a crucial role in regulating cardiac hypertrophy. Recent data from our lab has shown that, following ventricular pressure overload, GRK5, a primary cardiac GRK, facilitates maladaptive myocyte g
Externí odkaz:
https://doaj.org/article/f933052fcc7e42b0bf320c5f5af94e73
Autor:
Juliana Mira Hernandez, Christopher Y. Ko, Avery R. Mandel, Erin Y. Shen, Sonya Baidar, Ashley R. Christensen, Kim Hellgren, Stefano Morotti, Jody L. Martin, Bence Hegyi, Julie Bossuyt, Donald M. Bers
Publikováno v:
Journal of Molecular and Cellular Cardiology. 180:33-43
Autor:
Chidera C. Alim, Christopher Y. Ko, Juliana Mira Hernandez, Erin Y. Shen, Sonya Baidar, Ye Chen‐Izu, Donald M. Bers, Julie Bossuyt
Publikováno v:
The Journal of Physiology. 600:4865-4879
Autor:
Bence Hegyi, Juliana Mira Hernandez, Erin Y. Shen, Nima R. Habibi, Julie Bossuyt, Donald M. Bers
Publikováno v:
Circulation
Publikováno v:
Biophysical Journal. 122:382a-383a
Autor:
Juliana Mira Hernandez, Christopher Y. Ko, Avery Mandel, Erin Y. Shen, Ashley R. Christensen, Julie Bossuyt, Donald M. Bers
Publikováno v:
Biophysical Journal. 122:377a-378a