Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Julie Bernauer"'
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 7, p e1004404 (2015)
Argonaute (Ago) proteins and microRNAs (miRNAs) are central components in RNA interference, which is a key cellular mechanism for sequence-specific gene silencing. Despite intensive studies, molecular mechanisms of how Ago recognizes miRNA remain lar
Externí odkaz:
https://doaj.org/article/d6891f67164848be9b743bf0a01f5afd
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136444 (2015)
Cellular processes involve large numbers of RNA molecules. The functions of these RNA molecules and their binding to molecular machines are highly dependent on their 3D structures. One of the key challenges in RNA structure prediction and modeling is
Externí odkaz:
https://doaj.org/article/a3bbc53c2dab4653b7a61beefdf16351
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108928 (2014)
Protein-RNA complexes provide a wide range of essential functions in the cell. Their atomic experimental structure solving, despite essential to the understanding of these functions, is often difficult and expensive. Docking approaches that have been
Externí odkaz:
https://doaj.org/article/3abb68da459f471396e53343b264fd47
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18541 (2011)
A protein-protein docking procedure traditionally consists in two successive tasks: a search algorithm generates a large number of candidate conformations mimicking the complex existing in vivo between two proteins, and a scoring function is used to
Externí odkaz:
https://doaj.org/article/d795b15b2572438a8918c5e5870858dc
Autor:
Giannis Patronas, Dimitris Syrivelis, Paraskevas Bakopoulos, Prethvi Kashinkunti, Louis Capps, Nikos Argyris, Nikos Terzenidis, Eitan Zahavi, Luke Yeager, Elad Mentovich, Julie Bernauer
Publikováno v:
Optical Fiber Communication Conference (OFC) 2023.
We propose a programmable optical fabric design for Data Center networks that extends SDN to L1. We present experiments on our HPC/ML testbed leveraging the programmable network to automatically failover from hardware or software failures.
Autor:
Julie Bernauer, Prethvi Kashinkunti, Bryan Catanzaro, Matei Zaharia, Vijay Anand Korthikanti, Jared Casper, Amar Phanishayee, Dmitri Vainbrand, Patrick LeGresley, Mohammad Shoeybi, Deepak Narayanan, Mostofa Patwary
Publikováno v:
SC
Large language models have led to state-of-the-art accuracies across a range of tasks. However, training these models efficiently is challenging for two reasons: a) GPU memory capacity is limited, making it impossible to fit large models on even a mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f27b8feb99fc20d65d879c34b6e517d
http://arxiv.org/abs/2104.04473
http://arxiv.org/abs/2104.04473
Publikováno v:
Journal of Chemical Theory and Computation. 12:946-956
G protein-coupled receptors (GPCRs) act as conduits in the plasma membrane, facilitating cellular responses to physiological events by activating intracellular signal transduction pathways. Extracellular signaling molecules can induce conformational
Autor:
Julie Bernauer
Publikováno v:
IPDPS
Learn how hardware and software stacks enable not only quick prototyping, but also efficient large-scale production deployments. The tutorial will conclude with a discussion about hands-on deep learning training opportunities as well as free academic
Publikováno v:
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2017, 16, pp.2479-2486. ⟨10.1093/bioinformatics/btx175⟩
Bioinformatics, Oxford University Press (OUP), 2017, 16, pp.2479-2486. 〈10.1093/bioinformatics/btx175〉
Bioinformatics, 2017, 16, pp.2479-2486. ⟨10.1093/bioinformatics/btx175⟩
Bioinformatics, Oxford University Press (OUP), 2017, 16, pp.2479-2486. ⟨10.1093/bioinformatics/btx175⟩
Bioinformatics, Oxford University Press (OUP), 2017, 16, pp.2479-2486. 〈10.1093/bioinformatics/btx175〉
Bioinformatics, 2017, 16, pp.2479-2486. ⟨10.1093/bioinformatics/btx175⟩
Motivation Predicting the 3D structure of RNA molecules is a key feature towards predicting their functions. Methods which work at atomic or nucleotide level are not suitable for large molecules. In these cases, coarse-grained prediction methods aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b93df2af6fa510a3bf3056fcd72640
https://hal.archives-ouvertes.fr/hal-01589347
https://hal.archives-ouvertes.fr/hal-01589347
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1517
MicroRNA (miRNA) and Argonaute (AGO) protein together form the RNA-induced silencing complex (RISC) that plays an essential role in the regulation of gene expression. Elucidating the underlying mechanism of AGO-miRNA recognition is thus of great impo