Výsledky vyhledávání - "Julie B. Sedgwick"

Autor: William F. Calhoun, Julie B. Sedgwick, William W. Busse

Publikováno v: Eosinophils in Allergy and Inflammation ISBN: 9780367812591
Eosinophils in Allergy and Inflammation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cccc2c340a93d13bcd795d9153553bfd
https://doi.org/10.1201/9780367812591-24

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Human airway and peripheral blood eosinophils enhance Th1 and Th2 cytokine secretion

Autor: Elizabeth A. B. Kelly, William W. Busse, Julie B. Sedgwick, Nizar N. Jarjour, Sameer K. Mathur, Lin Ying Liu

Publikováno v: Allergy. 61:589-597

Background: The effector function of eosinophils involves their release of toxic granule proteins, reactive oxygen species, cytokines, and lipid mediators. Murine studies have demonstrated that eosinophils can also enhance T cell function. Whether hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb94c177d180f3312e81fb03221347c
https://doi.org/10.1111/j.1398-9995.2006.01060.x

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Effects of the very late adhesion molecule 4 antagonist WAY103 on human peripheral blood eosinophil vascular cell adhesion molecule 1–dependent functions

Autor: Julie B. Sedgwick, William W. Busse, Jeffrey D. Kennedy, Kristyn J. Jansen, Hirohito Kita

Publikováno v: Journal of Allergy and Clinical Immunology. 116:812-819

Eosinophil infiltration to the lung in allergic inflammation can be initiated by the tethering of circulating cells through very late adhesion molecule 4 (VLA-4; alpha4beta1, CD49d/CD29) to vascular cell adhesion molecule 1 (VCAM-1) expressed on pulm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1518e80ff05a59308adce80d031d2f
https://doi.org/10.1016/j.jaci.2005.07.003

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Expression of Interleukin-5– and Granulocyte Macrophage–Colony-Stimulating Factor–Responsive Genes in Blood and Airway Eosinophils

Autor: Mary Ellen Bates, Julie B. Sedgwick, Barbara A. Stout, Ekokobe Fonkem, Paul J. Bertics, James S. Malter, Lin Ying Liu, Elizabeth A. B. Kelly, William W. Busse, Vanderlene L. Kung, Douglas M. Bates, Stephane Esnault

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 30:736-743

Because interleukin (IL)-5 family cytokines are critical regulators of eosinophil development, recruitment, and activation, this study was initiated to identify proteins induced by these cytokines in eosinophils. Using oligonucleotide microarrays, nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2768bfb52e34e27360de273512a0a649
https://doi.org/10.1165/rcmb.2003-0234oc

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The promotion of eosinophil degranulation and adhesion to conjunctival epithelial cells by IgE-activated conjunctival mast cells

Autor: Julie B. Sedgwick, Neal P. Barney, James L. Stahl, Ellen B. Cook, Frank M. Graziano

Publikováno v: Annals of Allergy, Asthma & Immunology. 92:65-72

Background Allergen-mediated mast cell activation is a key feature of ocular allergic diseases. Evidence of eosinophil-derived mediators in tears and conjunctival biopsy specimens has been associated with chronic ocular allergic inflammation. Objecti

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https://doi.org/10.1016/s1081-1206(10)61712-7

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Oxidized Low-Density Lipoprotein Activates Migration and Degranulation of Human Granulocytes

Autor: William W. Busse, Heather A. Gerbyshak, Hirohito Kita, Young S. Hwang, Julie B. Sedgwick

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 29:702-709

Oxidized low-density lipoprotein (oxLDL) has been reported as a major participant in the pathogenesis of atherosclerosis. We hypothesized that oxLDL can also interact with granulocytes during inflammatory airway diseases, such as asthma. To test the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44574406fca82205ed0c4a078abe1878
https://doi.org/10.1165/rcmb.2002-0257oc

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Ligation of intercellular adhesion molecule 3 inhibits GM-CSF production by human eosinophils

Autor: Julie B. Sedgwick, Julie M. Kessel, William W. Busse, Rose F. Vrtis, James E. Gern

Publikováno v: Journal of Allergy and Clinical Immunology. 111:1024-1031

Background: Intercellular adhesion molecule 3 (ICAM-3) has recently been identified on the surface of eosinophils. Objective: The purpose of this study was to characterize ICAM-3 expression on eosinophils in response to cytokines and to determine whe

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https://doi.org/10.1067/mai.2003.1393

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Decreased Expression of Membrane IL-5 Receptor α on Human Eosinophils: II. IL-5 Down-Modulates Its Receptor Via a Proteinase-Mediated Process

Autor: William W. Busse, Elizabeth A. B. Kelly, Lin Ying Liu, Mary Ellen Bates, Rose F. Vrtis, Nizar N. Jarjour, Julie B. Sedgwick, James E. Gern, H. Kita

Publikováno v: The Journal of Immunology. 169:6459-6466

In the accompanying study, we demonstrated that following Ag challenge, membrane (m)IL-5Ralpha expression is attenuated on bronchoalveolar lavage eosinophils, soluble (s)IL-5Ralpha is detectable in BAL fluid in the absence of increased steady state l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fd833e06e1cb13858cb060fbabdae8
https://doi.org/10.4049/jimmunol.169.11.6459

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