Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julie Ann Naughton"'
Autor:
Catherine Robbe Masselot, Julie Ann Naughton, Steffen Backert, Michelle Kilcoyne, Felicity E. B. May, Gina Duggan, Helen Earley, Lokesh Joshi, Stephen D. Carrington, Marguerite Clyne, Ciara Dunne, Catherine Loughrey
Publikováno v:
Microorganisms; Volume 6; Issue 2; Pages: 44
Helicobacter pylori binds to the gastric mucin, MUC5AC, and to trefoil factor, TFF1, which has been shown to interact with gastric mucin. We examined the interactions of TFF1 and H. pylori with purified gastrointestinal mucins from different animal s
Autor:
Neil V. McFerran, Elizabeth M. Hoey, Alan Trudgett, Julie Ann Naughton, Brian J. Fennell, Gerard Brennan, Angus Bell, Ian Fairweather, James W. Barlow
Publikováno v:
Expert Opinion on Drug Discovery. 3:501-518
Parasitic diseases including malaria, leishmaniasis and schistosomiasis take a terrible toll of human life, health and productivity, especially in tropical and subtropical regions, and are also highly significant in animal health worldwide. Antiparas
Publikováno v:
Molecular and biochemical parasitology. 173(2)
Blood-stage malarial parasites (Plasmodium falciparum) digest large quantities of host haemoglobin during their asexual development in erythrocytes. The haemoglobin digestion pathway, involving a succession of cleavages by various peptidases, appears
Publikováno v:
Biochemical pharmacology. 75(8)
Malaria is a disease in desperate need of new chemotherapeutic approaches. Certain microtubule inhibitors, including vinblastine and taxol, have highly potent activity against malarial parasites and disrupt the normal microtubular structures of intra