Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Julie A. Skare"'
Autor:
Wim J.A. Meuling, Hervé Toutain, Rolf Fautz, Wouter H.J. Vaes, Julie A. Skare, W. Steiling, Kenneth R. Wehmeyer, Gerhard J. Nohynek, Eric K. Dufour, Mario Bramante, Albertus Th H.J. de Bie
Publikováno v:
Food and Chemical Toxicology. 81:71-80
Systemic exposure was measured in humans after hair dyeing with oxidative hair dyes containing 2.0% (A) or 1.0% (B) [14C]-p-phenylenediamine (PPD). Hair was dyed, rinsed, dried, clipped and shaved; blood and urine samples were collected for 48 hours
Use of read-across and computer-based predictive analysis for the safety assessment of PEG cocamines
Autor:
Julie A. Skare, Shengde Wu, Carol Eisenmann, Thomas Re, Viny Srinivasan, Stephanie Ringeissen, Karen Blackburn, Daniel Duche, Donald L. Bjerke
Publikováno v:
Regulatory Toxicology and Pharmacology. 71:515-528
In the European Union animal testing has been eliminated for cosmetic ingredients while the US Cosmetic Ingredient Review Expert Panel may request data from animal studies. The use of read-across and predictive toxicology provides a path for filling
Publikováno v:
Xenobiotica. 39:811-825
Aromatic amines and heterocyclic amines are widely used ingredients in permanent hair dyes. However, little has been published on their potential for oxidation via hepatic cytochrome P450s. Therefore, the authors screened nine such compounds for thei
Publikováno v:
Journal of Chromatography A. 1216:6970-6973
The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will help in identifying the environmental sources of s
Autor:
Gerhard J, Nohynek, Julie A, Skare, Wim J A, Meuling, Kenneth R, Wehmeyer, Albertus Th H J, de Bie, Wouter H J, Vaes, Eric K, Dufour, Rolf, Fautz, Winfried, Steiling, Mario, Bramante, Herve, Toutain
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 81
Systemic exposure was measured in humans after hair dyeing with oxidative hair dyes containing 2.0% (A) or 1.0% (B) [(14)C]-p-phenylenediamine (PPD). Hair was dyed, rinsed, dried, clipped and shaved; blood and urine samples were collected for 48 hour
Autor:
Bennett Van Houten, R. Julian Preston, Syril D. Pettit, Miriam Sander, Julie A. Skare, Jean Cadet, Gary M. Williams, B. Bhaskar Gollapudi, Lawrence J. Marnett, Raymond F. Novak, Daniel A. Casciano, Sheila M. Galloway
Publikováno v:
Toxicology and Applied Pharmacology. 208:1-20
In April 2004, the Health and Environmental Sciences Institute, a branch of the International Life Sciences Institute, with support from the National Institute of Environmental Health Sciences, organized a workshop to discuss the biological significa
Autor:
Edward Doyle, Robert Powrie, Lesley A. Stanley, Diane D’Angelo, Clifford R. Elcombe, Julie A. Skare
Publikováno v:
Toxicology. 210:147-157
p-Phenylenediamine (PPD) is a widely used ingredient in permanent hair dyes; however, little has been published on its metabolism, especially with respect to hepatic cytochrome P450 (CYP)-mediated oxidation. This is regarded as a key step in the acti
Autor:
Daniel J. Minnema, Andrew Parkinson, Robert C Bookstaff, Uma Sanzgiri, Julie A. Skare, Vincent A. Murphy
Publikováno v:
Toxicology and Applied Pharmacology. 141:584-594
The effects of doxylamine (as the succinate salt) on microsomal enzyme activity and serum thyroid hormone levels were examined in B6C3F1 mice following dietary exposure for 7 or 15 days (0, 40, 375, 750, or 1500 ppm in diet, expressed as free base do
Autor:
Julie A. Skare, Gary A. Thompson, John V. St. Peter, James H. Powell, Zebulun D. Horowitz, Terri T. Charles, Mark A. Heise, Chris Brezovic, Darrell A. Russell, Georgiana C. Salyers
Publikováno v:
Journal of Pharmaceutical Sciences. 85:1242-1247
The primary purpose of this study was to assess the influence of doxylamine and phenobarbital on antipyrine/metabolites pharmacokinetics and 6 beta-hydroxycortisol urinary excretion. This study was conducted in 48 healthy male human volunteers (16 pe
Publikováno v:
Mutagenesis. 25(1)
Hair dye ingredients frequently produce positive results in short-term in vitro genotoxicity tests, although results from in vivo assays are typically negative, especially for ingredients in use today. The use of hair dyes is quite widespread resulti