Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Julie A. Pigza"'
Autor:
Long Phi Dinh, Jian Sun, Courtney D. Glenn, Krunal Patel, Julie A. Pigza, Matthew G. Donahue, Larry Yet, Jacques J. Kessl
Publikováno v:
Viruses, Vol 14, Iss 7, p 1466 (2022)
Allosteric HIV-1 integrase (IN) inhibitors, or ALLINIs, are a new class of antiviral agents that bind at the dimer interface of the IN, away from the enzymatic catalytic site and block viral replication by triggering an aberrant multimerization of th
Externí odkaz:
https://doaj.org/article/f2d416b3b3bc4289b2abab616bc72f4e
Autor:
Nicholas G. Jentsch, Jared D. Hume, Emily B. Crull, Samer M. Beauti, Amy H. Pham, Julie A. Pigza, Jacques J. Kessl, Matthew G. Donahue
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2529-2536 (2018)
A convenient two-step synthesis of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate derivatives has been developed starting from commercially available 2-aminobenzoic acids. In step 1, the anthranilic acids are smoothly converted to isatoic anhydrides
Externí odkaz:
https://doaj.org/article/fbd91e864cd84c9da84a118b40063aa4
Autor:
Jian Sun, Jacques J. Kessl, Kaitlin A McNeely, Julie A. Pigza, Nicholas G. Jentsch, Chiyang Lama, Jared D. Hume, Alison P Hart, Matthew Garrett Donahue
Publikováno v:
ACS Medicinal Chemistry Letters. 9:1007-1012
[Image: see text] HIV-1 integrase multimerization inhibitors have recently been established as an effective class of antiretroviral agents due to their potent ability to inhibit viral replication. Specifically, quinoline-based inhibitors have been sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ff79914f4d441c9d2d1e09908647b7
https://doi.org/10.1021/acsmedchemlett.8b00269
https://doi.org/10.1021/acsmedchemlett.8b00269
Publikováno v:
Tetrahedron Letters. 58:3024-3027
We report an efficient two step process for the reduction of non-aromatic esters to the corresponding ethers via the intermediate TMS-protected acetal. The acetal formed after the first step can be carried on directly to the subsequent reduction to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::660011d1743dfdaa2d7b95bb7531d982
https://doi.org/10.1016/j.tetlet.2017.06.043
https://doi.org/10.1016/j.tetlet.2017.06.043
Autor:
Julie A. Pigza, Jared D. Hume, Jacques J. Kessl, Matthew Garrett Donahue, Jian Sun, Krunal Patel
Publikováno v:
The Journal of Biological Chemistry
During the integration step, human immunodeficiency virus type 1 integrase (IN) interacts with viral DNA and the cellular cofactor LEDGF/p75 to effectively integrate the reverse transcript into the host chromatin. Allosteric human immunodeficiency vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812afed44ebca78da55c911ffeaba508
https://doi.org/10.1016/j.jbc.2021.100363
https://doi.org/10.1016/j.jbc.2021.100363
Autor:
Emily B. Crull, Samer M. Beauti, Jared D. Hume, Amy H. Pham, Jacques J. Kessl, Nicholas G. Jentsch, Matthew Garrett Donahue, Julie A. Pigza
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2529-2536 (2018)
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2529-2536 (2018)
A convenient two-step synthesis of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate derivatives has been developed starting from commercially available 2-aminobenzoic acids. In step 1, the anthranilic acids are smoothly converted to isatoic anhydrides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ae380e1f278bb6b26e9c640fdc1393
https://pubmed.ncbi.nlm.nih.gov/30344776
https://pubmed.ncbi.nlm.nih.gov/30344776
Autor:
Robert V. Dennis, Sean W. Depner, Sarbajit Banerjee, Julie A. Pigza, Susan Budhoo, Tirandai Hemraj-Benny, Loren Condon
Publikováno v:
Materials Letters. 117:305-308
Single-walled carbon nanotubes (SWNTs) reinforced with uniform distribution of magnesium nanoparticles were synthesized by a solution reduction method using a Grignard reagent and lithium naphthalide. Magnesium nanoparticles were observed to be of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aef580626faeb7801d89bbd6a2e976ad
https://doi.org/10.1016/j.matlet.2013.12.032
https://doi.org/10.1016/j.matlet.2013.12.032
Autor:
Aroop Chandra, Jeffrey N. Johnston, Julie A. Pigza, Maren Pink, Jeong-Seok Han, Daniel Mutnick
Publikováno v:
The Journal of Organic Chemistry. 78:822-843
Serratezomine A is a member of the structurally diverse class of compounds known as the Lycopodium alkaloids. The key supporting studies and successful total synthesis of serratezomine A are described in this account. Significant features of the synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c3c6ff2a9af96584339d940c3dc0ff
https://doi.org/10.1021/jo302333s
https://doi.org/10.1021/jo302333s
Autor:
Julie A. Pigza, Tadeusz F. Molinski
Publikováno v:
Organic Letters. 12:1256-1259
The addition of allyl stannanes to (S)-4,5-dihydro-5-phenyl-2H-oxazinone (3) was achieved under Brønsted acid catalysis to give 2-allylmorpholinones with high diastereoselectivity (up to dr 14.2:1). The product of dimethylallyltributylstannane addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87fb1d0ae46611e59f117cbd1923446
https://doi.org/10.1021/ol1001126
https://doi.org/10.1021/ol1001126
Publikováno v:
Letters in Organic Chemistry. 6:224-228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7709c64cc27b160d1897ee1af6af4189
https://doi.org/10.2174/157017809787893046
https://doi.org/10.2174/157017809787893046