Zobrazeno 1 - 2
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pro vyhledávání: '"Julie A. McLear"'
Publikováno v:
Progress in Neurobiology. 97:190-204
The engineered antibody approach to Huntington's disease (HD) therapeutics is based on the premise that significantly lowering the levels of the primary misfolded mutant protein will reduce abnormal protein interactions and direct toxic effects of th
Publikováno v:
Molecular and Cellular Neuroscience. 33:260-273
Nestin-positive cells were targeted for pRb, p107 and p130 (pRb f ) inactivation by expression of T 121 , a truncated SV40 large T antigen that selectively binds to and inactivates pRb f . Cre expression was initiated under GFAP control, resulting in