Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julie A. MacDonald"'
Publikováno v:
Journal of Ovarian Research, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract Background Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. However, metabolic signatures between neoplasms can be unique, allowing for distinctions in malignancy, invasion
Externí odkaz:
https://doaj.org/article/8f958d4ae63c4bbca96483095ceec9bf
Publikováno v:
MethodsX, Vol 5, Iss , Pp 593-598 (2018)
Electron microscopy as a methodology for the study of mitochondria based on morphological features is a standard technique that has experienced little evolution over the course of several decades. This technology has identified heterogeneity of mitoc
Externí odkaz:
https://doaj.org/article/7c9e54c6230e421e9c30cc99c932f78e
Autor:
Julie A. MacDonald, Hannah C. Sheehan, Andrew Piasecki, Luciana R. Faustino, Charlotte Hauschildt, Victor Stolzenbach, Dori C. Woods, Jonathan L. Tilly
Publikováno v:
Stem cells and development.
Many adult somatic stem cell lineages are comprised of subpopulations that differ in gene expression, mitotic activity, and differentiation status. Here we explored if cellular heterogeneity also exists within oogonial stem cells (OSCs), and how chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55eae431404c2fc3f5c3df35f8d5dbc
https://pubmed.ncbi.nlm.nih.gov/36594561
https://pubmed.ncbi.nlm.nih.gov/36594561
Publikováno v:
Stem Cells Dev
Cells within tissues are routinely subjected to physiological stress and strain, arising from direct interactions with neighboring cells as well as with extracellular matrix components. Accordingly, there is tremendous interest in deciphering how cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ea63fb3b01f98a789598f1f3e5c97f
https://doi.org/10.1089/scd.2021.0086
https://doi.org/10.1089/scd.2021.0086
Autor:
Julie A. MacDonald, Chonthicha Satirapod, Minghan Sun, Jonathan L. Tilly, Ning Wang, Dori C. Woods
Publikováno v:
Aging (Albany NY)
Progressive loss of ovarian estrogen (E2) production is a hallmark feature of, if not a driving force behind, reproductive aging and the menopause. Recent genetic studies in mice have shown that female germline or oogonial stem cells (OSCs) contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ee38c6374ab1ce8b2f8b002c3b5c63
http://europepmc.org/articles/PMC7202493
http://europepmc.org/articles/PMC7202493
Autor:
Fleur Jochems, Julie A. MacDonald, Chrysiida Baltira, Veerle Daniels, Mark de Gooijer, Olaf Van Tellingen, Anthony Letai, René Bernards
Publikováno v:
Cancer Research. 83:PR013-PR013
Senescent cells rely on anti-apoptotic signaling for their survival, which can be targeted by senolytic agents. ABT-263 is a broad acting senolytic that targets anti-apoptotic proteins BCL-2, BCL-xL and BCL-W. Our group has shown that ABT-263 has a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f038e7b955c02815bcf371afd708da5e
https://doi.org/10.1158/1538-7445.agca22-pr013
https://doi.org/10.1158/1538-7445.agca22-pr013
Publikováno v:
MethodsX
MethodsX, Vol 5, Iss, Pp 593-598 (2018)
MethodsX, Vol 5, Iss, Pp 593-598 (2018)
Graphical abstract
Electron microscopy as a methodology for the study of mitochondria based on morphological features is a standard technique that has experienced little evolution over the course of several decades. This technology has identifie
Electron microscopy as a methodology for the study of mitochondria based on morphological features is a standard technique that has experienced little evolution over the course of several decades. This technology has identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a120b199124116128d4bda89d67f7fb8
http://europepmc.org/articles/PMC6031756
http://europepmc.org/articles/PMC6031756
Publikováno v:
Micron. 101:25-31
Mitochondria are dynamic intracellular organelles with diverse roles in tissue- and cell type-specific processes, extending beyond bioenergetics. In keeping with this array of functions, mitochondria are described as heterogeneous both between and wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10c7c978c1c871125c6c88c8577080b
https://doi.org/10.1016/j.micron.2017.05.002
https://doi.org/10.1016/j.micron.2017.05.002
Autor:
Alisha M. Bothun, Alexander R. Ivanov, Julie A. MacDonald, Konstantin Khrapko, Dori C. Woods, Jonathan L. Tilly, Somak Ray, Yuanwei Gao, Sofia Annis, Hannah Sheehan
Publikováno v:
Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-13 (2019)
Communications Biology, Vol 2, Iss 1, Pp 1-13 (2019)
Mitochondria are well-characterized regarding their function in both energy production and regulation of cell death; however, the heterogeneity that exists within mitochondrial populations is poorly understood. Typically analyzed as pooled samples co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106f67a04cd46120ce4e04207c0a1072
http://europepmc.org/articles/PMC6624292
http://europepmc.org/articles/PMC6624292