Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Julie A. Fischbeck"'
Autor:
Catherine A. Radebaugh, Venugopal Pujari, Jayanth V. Chodaparambil, Adam R. Almeida, Karolin Luger, Uma M. Muthurajan, Julie A. Fischbeck, Laurie A. Stargell
Publikováno v:
Journal of Molecular Biology. 404:1-15
Spn1/Iws1 plays essential roles in the regulation of gene expression by RNA polymerase II (RNAPII), and it is highly conserved in organisms ranging from yeast to humans. Spn1 physically and/or genetically interacts with RNAPII, TBP (TATA-binding prot
Publikováno v:
Genetics. 162:1605-1616
Little is known about TATA-binding protein (TBP) functions after recruitment to the TATA element, although several TBP mutants display postrecruitment defects. Here we describe a genetic screen for suppressors of a postrecruitment-defective TBP allel
Autor:
Sarah K. Lee, Lei Zhang, Julie A. Fischbeck, Xu Chen, Aaron G. L. Fletcher, Laurie A. Stargell
Publikováno v:
Genetics. 184(3)
A growing number of promoters have key components of the transcription machinery, such as TATA-binding protein (TBP) and RNA polymerase II (RNAPII), present at the promoter prior to activation of transcription. Thus, while transcriptional output unde
Publikováno v:
The Journal of biological chemistry. 281(32)
To reveal mechanistic differences in transcription initiation between variant TATA elements, in vivo and in vitro assays of the functional activity of 14 different sequences were compared. Variant elements exhibited particular degrees of activation i
Publikováno v:
Tissue engineering. 7(6)
The source of cells for tissue engineering applications remains a hurdle, predominantly for procedures in which there is insufficient time to harvest a patient's own cells. Animal cells are readily available, but undergo immune rejection. Rejection o