Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julie A. Edgeworth"'
Autor:
Christian Schmidt, Jeremie Fizet, Francesca Properzi, Mark Batchelor, Malin K. Sandberg, Julie A. Edgeworth, Louise Afran, Sammy Ho, Anjna Badhan, Steffi Klier, Jacqueline M. Linehan, Sebastian Brandner, Laszlo L. P. Hosszu, M. Howard Tattum, Parmjit Jat, Anthony R. Clarke, Peter C. Klöhn, Jonathan D. F. Wadsworth, Graham S. Jackson, John Collinge
Publikováno v:
Open Biology, Vol 5, Iss 12 (2015)
According to the protein-only hypothesis, infectious mammalian prions, which exist as distinct strains with discrete biological properties, consist of multichain assemblies of misfolded cellular prion protein (PrP). A critical test would be to produc
Externí odkaz:
https://doaj.org/article/d9df89cc5c84457ea1d505bc18d78e06
Autor:
Michael Farmer, John Collinge, Tracy Campbell, Graham S. Jackson, Paul Tavares, Julie Ann Edgeworth, Simon Mead, Jon Beck, Peter Rudge, Jessica Lowe, Anita Sicilia
Publikováno v:
The Lancet. 377:487-493
Summary Background Variant Creutzfeldt-Jakob disease (vCJD) is a fatal neurodegenerative disorder originating from exposure to bovine-spongiform-encephalopathy-like prions. Prion infections are associated with long and clinically silent incubations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0442b84a82a41094a4c32076a52a9d
https://doi.org/10.1016/s0140-6736(10)62308-2
https://doi.org/10.1016/s0140-6736(10)62308-2
Autor:
Graham S. Jackson, Jackie Linehan, Julie Ann Edgeworth, Anita Sicilia, Sebastian Brandner, John Collinge
Publikováno v:
The Journal of General Virology
Prions are comprised principally of aggregates of a misfolded host protein and cause fatal transmissible neurodegenerative disorders of mammals, such as variant Creutzfeldt–Jakob disease in humans and bovine spongiform encephalopathy in cattle. Pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a10c75473b9623c5a6e240fb6fb7ba5
https://doi.org/10.1099/vir.0.027201-0
https://doi.org/10.1099/vir.0.027201-0
Publikováno v:
Proceedings of the National Academy of Sciences. 106:3479-3483
Prions are comprised principally of aggregates of a misfolded host protein and cause fatal transmissible neurodegenerative disorders of humans and animals, such as variant Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Prions pose si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273e7e7012454c97e74f3cba5ffbbff4
https://doi.org/10.1073/pnas.0813342106
https://doi.org/10.1073/pnas.0813342106
Autor:
Justine Korteweg, Jesse Burk-Rafel, Graham S. Jackson, Catherine J. Mummery, John Collinge, Claire Thomas, Jonathan Mackey, Anita Sicilia, Patrick F. Chinnery, Simon Mead, Guosu Wang, Julie Ann Edgeworth, Sabah Abdilahi, Jonathan M. Schott
Importance Our study indicates a prototype blood-based variant Creutzfeldt-Jakob disease (vCJD) assay has sufficient sensitivity and specificity to justify a large study comparing vCJD prevalence in the United Kingdom with a bovine spongiform encepha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9259197ae415b6bf68a5be56339f6e91
https://europepmc.org/articles/PMC4158718/
https://europepmc.org/articles/PMC4158718/
Autor:
Graham S, Jackson, Jesse, Burk-Rafel, Julie A, Edgeworth, Anita, Sicilia, Sabah, Abdilahi, Justine, Korteweg, Jonathan, Mackey, Claire, Thomas, Guosu, Wang, Simon, Mead, John, Collinge
Publikováno v:
Blood. 123(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afc8cb72746bfe1ff1d897bf917fa119
https://pubmed.ncbi.nlm.nih.gov/24434999
https://pubmed.ncbi.nlm.nih.gov/24434999
Autor:
Sebastian Brandner, Nathalie Gros, Jackie Linehan, Graham S. Jackson, Susan Joiner, Julie Ann Edgeworth, Jonathan D. F. Wadsworth, Charles Weissmann, John Collinge, Jack Alden
Prions are transmissible agents that cause lethal neurodegeneration in humans and other mammals. Prions bind avidly to metal surfaces such as steel wires and, when surface-bound, can initiate infection of brain or cultured cells with remarkable effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee238356741c31ab7cf709cbfc607953
https://europepmc.org/articles/PMC2922516/
https://europepmc.org/articles/PMC2922516/