Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julie A. E. Irving"'
Autor:
Hayden L. Bell, Helen J. Blair, Mankaran Singh, Anthony V. Moorman, Olaf Heidenreich, Frederik W. van Delft, John Lunec, Julie A. E. Irving
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Outcomes for patients with relapsed acute lymphoblastic leukemia (ALL) are poor and there is a need for novel therapies to improve outcomes. Targeted inhibition of WEE1 with small-molecule inhibitor adavosertib (AZD1775) has emerg
Externí odkaz:
https://doaj.org/article/9deed2b8e0db4595931334af42559dac
Autor:
Richard, Gallon, Rachel, Phelps, Leigh, Betts, Christine, Hayes, Dino, Masic, Julie A E, Irving, Ciaron, McAnulty, Vaskar, Saha, Ajay, Vora, Katharina, Wimmer, Jayashree, Motwani, Christine, Macartney, John, Burn, Michael S, Jackson, Anthony V, Moorman, Mauro, Santibanez-Koref
Publikováno v:
Leukemia & Lymphoma. 64:217-220
Autor:
Stefan Schmidt, Julie A. E. Irving, Lynne Minto, Elizabeth Matheson, Lindsay Nicholson, Andreas Ploner, Walther Parson, Anita Kofler, Melanie Amort, Martin Erdel, Andy Hall, Reinhard Kofler
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(14)
Glucocorticoids (GCs) specifically induce apoptosis in malignant lymphoblasts and are thus pivotal in the treatment of acute lymphoblastic leukemia (ALL). However, GC-resistance is a therapeutic problem with an unclear molecular mechanism. We generat
Autor:
Julie A. E. Irving, Andrew G. Hall
Publikováno v:
Expert review of anticancer therapy. 1(1)
In this short review, we aim to bring together the most recent evidence implicating mismatch repair pathway defects as a cause of drug resistance to a spectrum of chemotherapeutic agents in a variety of cancers. Experimental and clinical studies are