Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Julie A., Leary"'
Publikováno v:
Biomolecules, Vol 3, Iss 4, Pp 905-922 (2013)
Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma. To better characterize in vivo protein function, compr
Externí odkaz:
https://doaj.org/article/ec4f0b87673c45e79fee70d6b60aa1e8
Autor:
Julie A. Leary
Publikováno v:
ACS Central Science, Vol 1, Iss 9, Pp 475-476 (2015)
Externí odkaz:
https://doaj.org/article/dfd835c7398f46eba2a88b1a5d18761a
Publikováno v:
PLoS Biology, Vol 3, Iss 8, p e250 (2005)
Sulfonucleotide reductases are a diverse family of enzymes that catalyze the first committed step of reductive sulfur assimilation. In this reaction, activated sulfate in the context of adenosine-5'-phosphosulfate (APS) or 3'-phosphoadenosine 5'-phos
Externí odkaz:
https://doaj.org/article/2a65b6c7ab004f469a779cf7b7c69a5f
Autor:
Jessica C. Seeliger, Cynthia M. Holsclaw, Julie A. Leary, Viven C. Solomon, Carolyn R. Bertozzi, Mary Lou Previti, Megan H. Touchette
Publikováno v:
Journal of bacteriology, vol 197, iss 1
Trehalose glycolipids are found in many bacteria in the suborder Corynebacterineae , but methyl-branched acyltrehaloses are exclusive to virulent species such as the human pathogen Mycobacterium tuberculosis . In M. tuberculosis , the acyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c2c63d387942364fe171a9d5ccd600
https://doi.org/10.1128/jb.02015-14
https://doi.org/10.1128/jb.02015-14
Autor:
Daniel K. Nomura, Gabriela K. Fragiadakis, Kimberly M. Sogi, Cynthia M. Holsclaw, Carolyn R. Bertozzi, Julie A. Leary
Publikováno v:
ACS infectious diseases. 2(11)
Sulfomenaquinone (SMK) is a recently identified metabolite that is unique to the Mycobacterium tuberculosis (M. tuberculosis) complex and is shown to modulate its virulence. Here, we report the identification of the SMK biosynthetic operon that, in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4670b6fb699196b696e4cb7a519c8f7b
https://pubmed.ncbi.nlm.nih.gov/27933784
https://pubmed.ncbi.nlm.nih.gov/27933784
Autor:
Guillaume Pilot, Julie A. Leary, Weitao Jia, Shi Yu, Réjane Pratelli, Damian D. Guerra, Sonia M. Chapiro, Judy Callis
Publikováno v:
The Journal of biological chemistry, vol 292, iss 9
Intercellular amino acid transport is essential for the growth of all multicellular organisms, and its dysregulation is implicated in developmental disorders. By an unknown mechanism, amino acid efflux is stimulated in plants by overexpression of a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae037ac22fcf0bb31cf4f69573cabca
https://pubmed.ncbi.nlm.nih.gov/28100770
https://pubmed.ncbi.nlm.nih.gov/28100770
Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography
Autor:
James Austin, Julie A. Leary, Jeremy E. Turnbull, Jemma Blocksidge, Scott E. Guimond, Maitreyi Shivkumar, Rebecca L. Miller
Publikováno v:
Analytical Chemistry
The complexity of heparin and heparan sulfate saccharides makes their purification, including many isomeric structures, very challenging and is a bottleneck for structure-activity studies. High-resolution separations have been achieved by strong anio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734a0d1099fca9c5f05c7351af42d28e
https://pubmed.ncbi.nlm.nih.gov/27801575
https://pubmed.ncbi.nlm.nih.gov/27801575
Autor:
Cynthia M. Holsclaw, Andrew B. Dykstra, Wei Wei, Rebecca L. Miller, Jeremy E. Turnbull, Julie A. Leary
Publikováno v:
ANALYTICAL CHEMISTRY
Chemokine-GAG interactions are crucial to facilitate chemokine immobilization, resulting in the formation of chemokine gradients that guide cell migration. Here we demonstrate chromatographic isolation and purification of two heparin hexasaccharide i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380ccee4b5f0bc728911fb34d9844d6c
https://pubmed.ncbi.nlm.nih.gov/27801570
https://pubmed.ncbi.nlm.nih.gov/27801570
Autor:
Rainer Kalscheuer, Carolyn R. Bertozzi, John C. Jewett, Marina Alber, Cynthia M. Holsclaw, Julie A. Leary, Benjamin M. Swarts, Douglas M. Fox, M. Sloan Siegrist
Publikováno v:
Journal of the American Chemical Society
Mycobacteria, including the pathogen Mycobacterium tuberculosis, use the non-mammalian disaccharide trehalose as a precursor for essential cell-wall glycolipids and other metabolites. Here we describe a strategy for exploiting trehalose metabolic pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16899bdc405ff4154a22097b1978998f
https://doi.org/10.1021/ja3062419
https://doi.org/10.1021/ja3062419
Autor:
Milady R. Niñonuevo, Julie A. Leary
Publikováno v:
Analytical Chemistry. 84:3208-3214
Unique to ion mobility mass spectrometry (IM-MS) is the ability to provide collision cross section (CCS) data and the capacity to delineate any dissociation and/or unfolding of protein complexes. The strong correlation of the experimentally determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92fa187f4bad8b5e5b0cf568f069e31
https://doi.org/10.1021/ac2030249
https://doi.org/10.1021/ac2030249